Robert W Dougherty

US Patent:

6451288, Sep 17, 2002

Filed:

Aug 24, 2000

Appl. No.:

09/645161

Inventors:

Sammy Ray Shaver - Chapel Hill NC
William Pendergast - Durham NC
Benjamin Yerxa - Raleigh NC
Janet L. Rideout - Raleigh NC
Robert Dougherty - Chapel Hill NC
Dallas Croom - Apex NC

Assignee:

The University of North Carolina at Chapel Hill - Chapel Hill NC
Inspire Pharmaceuticals, Inc. - Durham NC

International Classification:

A61K 912

US Classification:

424 45, 424 46, 424489, 514 52, 514851, 514826

Abstract:

Compounds of Formula I: wherein: X , and X are each independently either O or S ; X and X are each independently either âH or âOH, with the proviso that X and X are not simultaneously âH; R is selected from the group consisting of O, imido, methylene and dihalomethylene; R is selected from the group consisting of H, halo, alkyl, substituted alkyl, alkoxyl, nitro and azido; R is selected from the group consisting of H, alkyl, acyl, aryl, and arylalkyl; and R is selected from the group consisting of âORâ, âSRâ, âNRâ, and âNRâRâ, wherein Râ and Râ are independently selected from the group consisting of H, alkyl, substituted alkyl, aryl, substituted aryl, arylalkyl, alkoxyl, and aryloxyl, with the proviso that Râ is absent when R is double bonded from an oxygen or sulfur atom to the carbon at the 4-position of the pyrimidine ring, are used in methods of hydrating lung mucus secretions and treating lung disorders such as cystic fibrosis, ventilator-associated pneumonia, chronic bronchitis, chronic obstructive pulmonary disorder and primary ciliary dyskinesia. Pharmaceutical compositions containing compounds of Formula I, and novel compounds of Formula I are also described.

US Patent:

7637961, Dec 29, 2009

Filed:

Feb 21, 2003

Appl. No.:

10/372567

Inventors:

Anton Georges El A'mma - Phoenixville PA, US
Robert Francis Dougherty - Hatboro PA, US

Assignee:

Rohm and Haas Company - Philadelphia PA

International Classification:

C14C 9/02
C14C 3/00

US Classification:

8 9433, 8 941 R, 8 9421, 510275, 427389, 252 857, 525183, 5253297

Abstract:

An oligomeric composition containing oligomers and at least one stabilizing component is provided. An aqueous dispersion composition containing the oligomeric composition is useful for treating tanned leather to provide leather with increased softness or strength. Also provided are a method of treating tanned leather using the composition and an article containing the treated leather.

US Patent:

7805486, Sep 28, 2010

Filed:

May 27, 2005

Appl. No.:

11/138361

Inventors:

Dean H. Hering - Raleigh NC, US
John R. Dixon - Vienna VA, US
Robert J. Dougherty - Vienna VA, US

Assignee:

Netcentrics, Inc. - Herndon VA

International Classification:

G06F 15/16

US Classification:

709204

Abstract:

A meeting effectiveness indicator provides information to participants of a meeting. The information includes messages that the meeting has gone off topic, and resources are being wasted. Participants within a room or local vicinity of the indicator used wired or wireless transmitters to send indications that the meeting is going off topic. Remote participants linked to a network also send indications via a network interface. Once a total number of indications reaches a warning threshold, the indicator warns the participants that the meeting is going off topic with a warning message. If additional indications are received, then the total number of indications will reach a tangent threshold, and the participants are alerted using a tangent message that the meeting is off topic.

US Patent:

20080058456, Mar 6, 2008

Filed:

Aug 21, 2007

Appl. No.:

11/894436

Inventors:

Ari K. Kar - Warrington PA, US
Robert F. Dougherty - Hatboro PA, US

International Classification:

C08J 3/00

US Classification:

524457

Abstract:

The present invention provides aqueous amphiphilic emulsion copolymer compositions comprising one or more aqueous phase copolymer, a residue of one or more hydrophilic chain transfer agent, and a residue of one or more hydrophobic chain transfer agent, as well as methods of making such copolymers in water or an aqueous liquid by copolymerizing a monomer component of from 20 to 80 wt. %, based on the weight of the monomer component, of a hydrophilic group-containing monomer and the remainder of a copolymerizable ethylenically unsaturated monomer or prepolymer in the presence of a mixed chain transfer agent component comprising a hydrophilic chain transfer agent, such as 3-mercaptopropionic acid, and a hydrophobic chain transfer agent, such as N-dodecyl mercaptan. The aqueous amphiphilic emulsion copolymers of the present invention are storage stable and exhibit excellent viscosity control even in high solids compositions, e.g. from 50 to 80 wt. % of the composition. The high solids compositions can be diluted at the point of use, thus reducing shipment costs.

US Patent:

20100141161, Jun 10, 2010

Filed:

Mar 5, 2009

Appl. No.:

12/398266

Inventors:

Dean H. Hering - Raleigh NC, US
Robert J. Dougherty - Herndon VA, US
John R. Dixon - Herndon VA, US

Assignee:

NetCentrics Corporation - Herndon VA

International Classification:

F21S 4/00

US Classification:

315185 S

Abstract:

The present disclosure provides a decorative light string system comprising a light string comprising a plurality of lighting bulbs arranged electrically in series, wherein each light bulb comprises at least two LED chips, wherein half of said LED chips are connected in parallel and wherein half of said LED chips are connected in reverse parallel; and a switch box, and a switchbox comprising a switch having at least a first position and a second position, wherein when the switch is in the first position, a first pole is engaged allowing passage of a positive waveform lighting the LEDs connected in parallel, and wherein when the switch is in a second position, a second pole is engaged allowing passage of a negative waveform lighting the LEDs connected in reverse parallel; as well as methods of using said decorative light string system.

US Patent:

20110091621, Apr 21, 2011

Filed:

Jun 19, 2009

Appl. No.:

12/999679

Inventors:

Dean Howard Hering - Raleigh NC, US
John Robert Dixon - Herndon VA, US
Robert John Dougherty - Herndon VA, US

Assignee:

NETCENTRICS CORPORATION - Raleigh NC

International Classification:

A47J 37/06
A47J 37/00
A23L 1/01

US Classification:

426466, 99449

Abstract:

A food toasting device comprising a pouch and optionally, a handle. A method of using the food toasting device comprising placing a desired quantity of a food product, such as nuts, in the pouch of the food toasting device, placing the food toasting device into an appliance for heating, turning on the appliance so that the food product is exposed to the desired amount of heat, waiting until the food product is sufficiently toasted, and removing the food toasting device containing the food product from the appliance.

US Patent:

20110210677, Sep 1, 2011

Filed:

Feb 24, 2011

Appl. No.:

13/034190

Inventors:

Dean H. Hering - Raleigh NC, US
Robert J. Dougherty - Herndon VA, US
John R. Dixon - Herndon VA, US

Assignee:

NetCENTRICS CORPORATION - Vienna VA

International Classification:

H05B 37/02
F21S 4/00
F21V 9/00
H01R 13/66
H01R 43/00

US Classification:

315185 R, 36224906, 362231, 43962021, 29825

Abstract:

The present disclosure provides a decorative light string system comprising a light string comprising a plurality of lighting bulbs arranged electrically in series, wherein each light bulb comprises at least two LED chips, wherein half of said LED chips are connected in parallel and wherein half of said LED chips are connected in reverse parallel; and an adapter comprising a rectifier, wherein when the plug of the light string is plugged into the outlet adapter in a first orientation, the rectifier allows passage of a half-rectified wave lighting the LEDs connected in parallel, and wherein when the plug of the light string is plugged into the outlet adapter in a second orientation, the rectifier allows passage of a half-rectified wave lighting the LEDs connected in reverse parallel. Also included are methods of using said adapter and said decorative light string system.

US Patent:

60225270, Feb 8, 2000

Filed:

Jul 13, 1999

Appl. No.:

9/352390

Inventors:

Richard C. Boucher - Chapel Hill NC
Sammy Ray Shaver - Chapel Hill NC
William Pendergast - Durham NC
Benjamin Yerxa - Raleigh NC
Janet L. Rideout - Raleigh NC
Robert Dougherty - Chapel Hill NC
Dallas Croom - Apex NC

Assignee:

The University of North Carolina at Chapel Hill - Chapel Hill NC
Inspire Pharmaceuticals, Inc. - Durham NC

International Classification:

A61K 912

US Classification:

424 45

Abstract:

Compounds of Formula I: ##STR1## wherein: X. sub. 1, and X. sub. 2 are each independently either O. sup. - or S. sup. - ; X. sub. 3 and X. sub. 4 are each independently either --H or --OH, with the proviso that X. sub. 3 and X. sub. 4 are not simultaneously --H; R. sub. 1 is selected from the group consisting of O, imido, methylene and dihalomethylene; R. sub. 2 is selected from the group consisting of H, halo, alkyl, substituted alkyl, alkoxyl, nitro and azido; R. sub. 3 is selected from the group consisting of H, alkyl, acyl, aryl, and arylalkyl; and R. sub. 4 is selected from the group consisting of --OR', --SR', --NR', and --NR'R", wherein R' and R" are independently selected from the group consisting of H, alkyl, substituted alkyl, aryl, substituted aryl, arylalkyl, alkoxyl, and aryloxyl, with the proviso that R' is absent when R. sub. 4 is double bonded from an oxygen or sulfur atom to the carbon at the 4-position of the pyrimidine ring, are used in methods of hydrating lung mucus secretions and treating lung disorders such as cystic fibrosis, ventilator-associated pneumonia, chronic bronchitis, chronic obstructive pulmonary disorder and primary ciliary dyskinesia. Pharmaceutical compositions containing compounds of Formula I, and novel compounds of Formula I are also described.

Address:

3614 Cole Ml Rd, Durham, NC 27712

VIN:

3FAHP07ZX7R152449

Make:

FORD

Model:

FUSION

Year:

2007