Robert H O'Neil

US Patent:

6852522, Feb 8, 2005

Filed:

Nov 28, 2000

Appl. No.:

09/724419

Inventors:

Peter Palese - Leonia NJ, US
Adolfo Garcia-Sastre - New York NY, US
Robert O'Neil - New York NY, US

Assignee:

Mount Sinai School of Medicine of New York University - New York NY

International Classification:

C12N007/00

US Classification:

435239, 4352351, 435237, 435325

Abstract:

The present invention relates, to novel methods and substrates for the propagation of viruses. The invention relates to IFN-deficient substrates and methods for propagating viruses in these unconventional substrates. In particular, the invention relates to methods of propagating viruses in immature embryonated eggs, preferably six- to nine-day-old chicken eggs. The methods of the invention are particularly attractive for growing viruses suitable for use in vaccine and pharmaceutical formulations.

US Patent:

7494808, Feb 24, 2009

Filed:

Sep 20, 2004

Appl. No.:

10/945718

Inventors:

Peter Palese - Leonia NJ, US
Robert O'Neil - New York NY, US

Assignee:

Mount Sinai School of Medicine of New York University - New York NY

International Classification:

C12N 5/00

US Classification:

435325, 4352351

Abstract:

The present invention relates, to novel methods and substrates for the propagation of viruses. The invention relates to IFN-deficient substrates and methods for propagating viruses in these unconventional substrates. In particular, the invention relates to methods of propagating viruses in immature embryonated eggs, preferably six- to nine-day-old chicken eggs. The methods of the invention are particularly attractive for growing viruses suitable for use in vaccine and pharmaceutical formulations.

US Patent:

20090203114, Aug 13, 2009

Filed:

Feb 2, 2009

Appl. No.:

12/364243

Inventors:

Peter Palese - Leonia NJ, US
Adolfo Garcia-Sastre - New York NY, US
Robert E. O'Neil - New York NY, US

International Classification:

C12N 7/00

US Classification:

4352351

Abstract:

The present invention relates, to novel methods and substrates for the propagation of viruses. The invention relates to IFN-deficient substrates and methods for propagating viruses in these unconventional substrates. In particular, the invention relates to methods of propagating viruses in immature embryonated eggs, preferably six- to nine-day-old chicken eggs. The methods of the invention are particularly attractive for growing viruses suitable for use in vaccine and pharmaceutical formulations.

US Patent:

20120261448, Oct 18, 2012

Filed:

Apr 11, 2012

Appl. No.:

13/506318

Inventors:

Robert M. O'Neil - Santa Monica CA, US

International Classification:

B60R 7/05

US Classification:

224277

Abstract:

The invention is an automobile license plate mounting apparatus adapted to be coupled to or incorporated into a vehicle visor. A substantially rectangular, planar member is provided with securing means extending upwardly from the bottom and side edges of the front surface of said planar member. The securing member includes a contiguous flange extending from the edges of said planar member and a clamping panel disposed perpendicular to said contiguous flange and parallel to the front surface of said planar member to maintain the license plate adjacent the front surface of the planar panel. First and second securing members are affixed to the rear surface of the rectangular panel to secure the license plate holder to a vehicle visor. The securing members are obliquely positioned with respect to each other to horizontally position the license plate holder.