Robert Hamilton Potter

US Patent:

7078208, Jul 18, 2006

Filed:

May 1, 2001

Appl. No.:

09/845157

Inventors:

Michael D. Smith - Rockville MD, US
Robert Jason Potter - Frederick MD, US
Gulshan Dhariwal - Potomac MD, US
Gary F. Gerard - Frederick MD, US
Kim Rosenthal - Laytonsville MD, US

Assignee:

Invitrogen Corporation - Carlsbad CA

International Classification:

C12N 9/12

US Classification:

435194, 435 911, 435 912

Abstract:

The present invention is in the fields of molecular and cellular biology. The invention is generally related to reverse transcriptase enzymes and methods for the reverse transcription of nucleic acid molecules, especially messenger RNA molecules. Specifically, the invention relates to reverse transcriptase enzymes which have been mutated or modified to increase thermostability, decrease terminal deoxynucleotidyl transferase activity, and/or increase fidelity, and to methods of producing, amplifying or sequencing nucleic acid molecules (particularly cDNA molecules) using these reverse transcriptase enzymes or compositions. The invention also relates to nucleic acid molecules produced by these methods and to the use of such nucleic acid molecules to produce desired polypeptides. The invention also concerns kits comprising such enzymes or compositions.

US Patent:

8167702, May 1, 2012

Filed:

Mar 30, 2009

Appl. No.:

12/414516

Inventors:

Willem Polak - Glen Echo MD, US
Robert J. Potter - Alexandria VA, US

Assignee:

Lottofone, Inc. - Alexandria VA

International Classification:

A63F 13/00

US Classification:

463 17

Abstract:

A prepaid wagering card and a system and method for playing the lottery over a telephone line using the prepaid wagering card are provided. The prepaid wagering card includes information that makes it convenient to obtain the prepaid wagering card and use it to wager sets of numbers listed thereon, while also ensuring that the information remains secure. Participating in a lottery using the prepaid wagering card simply involves calling a wagering system from a telephone and providing requested information. Thus, a user can purchase a prepaid wagering card and decide on which scheduled lottery to actually wager using the prepaid wagering card.

US Patent:

20040209276, Oct 21, 2004

Filed:

Sep 15, 2003

Appl. No.:

10/661819

Inventors:

Michael Smith - Rockville MD, US
Robert Potter - San Marcos CA, US
Gulshan Dhariwal - Potomac MD, US
Gary Gerard - Frederick MD, US
Kim Rosenthal - Laytonsville MD, US
Jun Lee - San Diego CA, US

International Classification:

C12Q001/68
C07H021/04
C12P019/34
C12N009/22
C12N015/74

US Classification:

435/006000, 435/069100, 435/091200, 435/199000, 435/252300, 435/320100, 536/023200

Abstract:

The present invention is in the fields of molecular and cellular biology. The invention is generally related to reverse transcriptase enzymes and methods for the reverse transcription of nucleic acid molecules, especially messenger RNA molecules. Specifically, the invention relates to reverse transcriptase enzymes which have been mutated or modified to increase thermostability, decrease terminal deoxynucleotidyl transferase activity, and/or increase fidelity, and to methods of producing, amplifying or sequencing nucleic acid molecules (particularly cDNA molecules) using these reverse transcriptase enzymes or compositions. The invention also relates to nucleic acid molecules produced by these methods and to the use of such nucleic acid molecules to produce desired polypeptides. The invention also concerns kits comprising such enzymes or compositions.

US Patent:

20050130736, Jun 16, 2005

Filed:

Dec 12, 2003

Appl. No.:

10/733648

Inventors:

Willem Polak - Glen Echo MD, US
Robert Potter - Alexandria VA, US

International Classification:

G06F019/00
G06F017/00

US Classification:

463025000

Abstract:

A prepaid wagering card and a system and method for playing the lottery over a telephone line using the prepaid wagering card are provided. The prepaid wagering card includes information that makes it convenient to obtain the prepaid wagering card and use it to wager sets of numbers listed thereon, while also ensuring that the information remains secure. Participating in a lottery using the prepaid wagering card simply involves calling a wagering system from a telephone and providing requested information. Thus, a user can purchase a prepaid wagering card and decide on which scheduled lottery to actually wager using the prepaid wagering card.

US Patent:

20060211103, Sep 21, 2006

Filed:

May 22, 2006

Appl. No.:

11/437681

Inventors:

Michael Smith - Rockville MD, US
Robert Potter - Frederick MD, US
Gulshan Dhariwal - Potomac MD, US
Gary Gerard - Frederick MD, US
Kim Rosenthal - Laytonsville MD, US

Assignee:

Invitrogen Corporation - Carlsbad CA

International Classification:

C12N 9/22

US Classification:

435199000

Abstract:

The present invention is in the fields of molecular and cellular biology. The invention is generally related to reverse transcriptase enzymes and methods for the reverse transcription of nucleic acid molecules, especially messenger RNA molecules. Specifically, the invention relates to reverse transcriptase enzymes which have been mutated or modified to increase thermostability, decrease terminal deoxynucleotidyl transferase activity, and/or increase fidelity, and to methods of producing, amplifying or sequencing nucleic acid molecules (particularly cDNA molecules) using these reverse transcriptase enzymes or compositions. The invention also relates to nucleic acid molecules produced by these methods and to the use of such nucleic acid molecules to produce desired polypeptides. The invention also concerns kits comprising such enzymes or compositions.

US Patent:

20070141592, Jun 21, 2007

Filed:

Jul 25, 2006

Appl. No.:

11/492194

Inventors:

Michael Smith - Rockville MD, US
Robert Potter - San Marcos CA, US
Gulshan Dhariwal - Potomac MD, US
Gary Gerard - Frederick MD, US
Kim Rosenthal - Laytonsille MD, US
Jun Lee - San Diego CA, US

International Classification:

C12Q 1/68
C07H 21/04
C12P 21/06
C12N 9/22
C12N 15/86

US Classification:

435006000, 435069100, 435199000, 435456000, 435325000, 536023200

Abstract:

The present invention is in the fields of molecular and cellular biology. The invention is generally related to reverse transcriptase enzymes and methods for the reverse transcription of nucleic acid molecules, especially messenger RNA molecules. Specifically, the invention relates to reverse transcriptase enzymes which have been mutated or modified to increase thermostability, decrease terminal deoxynucleotidyl transferase activity, and/or increase fidelity, and to methods of producing, amplifying or sequencing nucleic acid molecules (particularly cDNA molecules) using these reverse transcriptase enzymes or compositions. The invention also relates to nucleic acid molecules produced by these methods and to the use of such nucleic acid molecules to produce desired polypeptides. The invention also concerns kits comprising such enzymes or compositions.

US Patent:

20100015683, Jan 21, 2010

Filed:

Sep 2, 2009

Appl. No.:

12/553061

Inventors:

Michael D. Smith - Rockville MD, US
Robert Jason Potter - San Marcos CA, US
Gulsham Dhariwal - Potomac MD, US
Gary F. Gerard - Frederick MD, US
Kim Rosenthal - Laytonsville MD, US

Assignee:

LIFE TECHNOLOGIES CORPORATION - Carlsbad CA

International Classification:

C12N 9/00

US Classification:

435183

Abstract:

The present invention is in the fields of molecular and cellular biology. The invention is generally related to reverse transcriptase enzymes and methods for the reverse transcription of nucleic acid molecules, especially messenger RNA molecules. Specifically, the invention relates to reverse transcriptase enzymes which have been mutated or modified to increase thermostability, decrease terminal deoxynucleotidyl transferase activity, and/or increase fidelity, and to methods of producing, amplifying or sequencing nucleic acid molecules (particularly cDNA molecules) using these reverse transcriptase enzymes or compositions. The invention also relates to nucleic acid molecules produced by these methods and to the use of such nucleic acid molecules to produce desired polypeptides. The invention also concerns kits comprising such enzymes or compositions.

US Patent:

20110081704, Apr 7, 2011

Filed:

Aug 23, 2010

Appl. No.:

12/861797

Inventors:

Michael D. Smith - Rockville MD, US
Robert Jason Potter - San Marcos CA, US
Gulshan Dhariwal - Potomac MD, US
Gary F. Gerard - Frederick MD, US
Kim Rosenthal - Laytonsville MD, US

Assignee:

LIFE TECHNOLOGIES CORPORATION - Carlsbad CA

International Classification:

C12N 9/12

US Classification:

435194

Abstract:

The present invention is in the fields of molecular and cellular biology. The invention is generally related to reverse transcriptase enzymes and methods for the reverse transcription of nucleic acid molecules, especially messenger RNA molecules. Specifically, the invention relates to reverse transcriptase enzymes which have been mutated or modified to increase thermostability, decrease terminal deoxynucleotidyl transferase activity, and/or increase fidelity, and to methods of producing, amplifying or sequencing nucleic acid molecules (particularly cDNA molecules) using these reverse transcriptase enzymes or compositions. The invention also relates to nucleic acid molecules produced by these methods and to the use of such nucleic acid molecules to produce desired polypeptides. The invention also concerns kits comprising such enzymes or compositions.