Robert Edward Powers

US Patent:

6684162, Jan 27, 2004

Filed:

Jan 25, 2001

Appl. No.:

09/770834

Inventors:

Kevin Delos Parris - Auburndale MA
William Stuart Somers - Cambridge MA
Amy Szepui Tam - Framingham MA
Laura Long Lin - Weston MA
Mark Lloyd Stahl - Lexington MA
Robert Powers - Westford MA

Assignee:

Wyeth - Madison NY
Millennium Pharmaceuticals, Inc. - Cambridge MA

International Classification:

G06F 1900

US Classification:

702 27, 436 4, 435 71, 435 72

Abstract:

This invention is directed to the crystal structure of Acyl Carrier Protein Synthase (ACPS) complexed with Acyl Carrier Protein (ACP), the solution structure of ACP, and to the use of these structures in rational drug design methods to identify agents that may interact with active sites of ACPS and ACP, and to the testing of these agents to identify agents that may represent novel antibiotics.

US Patent:

20020046394, Apr 18, 2002

Filed:

Dec 6, 2000

Appl. No.:

09/731678

Inventors:

Sung-Hee Do - Lexington MA, US
Nam suh - Sudbury MA, US
Robert Powers - Boston MA, US
Derrick Tate - Somerville MA, US

International Classification:

G06F009/44

US Classification:

717/108000

Abstract:

A system and method for producing software code is provided. In particular, a new software design methodology is provided that is based on axiomatic design theory. In one aspect, axiomatic design theory is adapted for use in designing object-oriented software programs. This methodology overcomes the shortcomings of various software design strategies including extensive software development and debugging time and the need for extensive maintenance. Because traditional software design strategies are not heuristic and do not provide basic principles for the development of good software systems, bad design habits produce poor quality software. A design framework using axiomatic design for software overcomes many of the shortcomings of current software design techniques: high maintenance costs, limited reusability, the need for extensive debugging and testing, poor documentation, and limited extensibility of the software, all of which result in high development cost of software.

US Patent:

20040078147, Apr 22, 2004

Filed:

Nov 19, 2003

Appl. No.:

10/717138

Inventors:

Kevin Parris - Auburndale MA, US
William Somers - Cambridge MA, US
Amy Tam - Medford MA, US
Laura Lin - Weston MA, US
Mark Stahl - Lexington MA, US
Robert Powers - Westford MA, US

International Classification:

G06F019/00
G01N033/48
G01N033/50
C12N009/10

US Classification:

702/019000, 435/193000

Abstract:

This invention is directed to the crystal structure of Acyl Carrier Protein Synthase (ACPS) complexed with Acyl Carrier Protein (ACP), the solution structure of ACP, and to the use of these structures in rational drug design methods to identify agents that may interact with active sites of ACPS and ACP, and to the testing of these agents to identify agents that may represent novel antibiotics.

US Patent:

53995473, Mar 21, 1995

Filed:

Sep 17, 1993

Appl. No.:

8/122623

Inventors:

Yehia Z. Negm - Braintree MA
George O. Zimmerman - South Hamilton MA
Robert E. Powers - East Boston MA

Assignee:

Trustees of Boston University - Boston MA

International Classification:

B05D 302
B05D 512

US Classification:

505430

Abstract:

The present invention provides a methodology for increasing the critical current density carried by high transition temperature; superconductive materials. The methodology is employed using any Noble metal to form an electrically conductive coating; and is used with any high transition temperature superconductive material conventionally known. The resulting improved superconducting material demonstrates an enhanced critical current density capability in the order of 48%; and substantially decreases the degradation of the critical current density in the presence of an applied magnetic field; and offers a range of other advantages including environmental degradation protection, an increased mechanical strength, and an improved capability for adding electrical contacts.

US Patent:

43397484, Jul 13, 1982

Filed:

Apr 8, 1980

Appl. No.:

6/138311

Inventors:

John K. Guscott - Lynnfield MA
Robert Powers - Norwell MA

Assignee:

American District Telegraph Company - New York NY

International Classification:

G02B 510
G08B 1318

US Classification:

340555

Abstract:

A passive infrared detection system which exhibits a consistent optical aperture and sensitivity over different operating ranges. The system includes a mirror assembly having a plurality of spherical segments arranged in two or more ranks, each corresponding to a different operating range. Each mirror segment is disposed at its respective focal length from a detector, and is of a size and configuration to provide an intended optical aperture to achieve uniform detection sensitivity irrespective of the range of the target.

US Patent:

51685248, Dec 1, 1992

Filed:

Aug 17, 1989

Appl. No.:

7/395449

Inventors:

John P. Kroeker - Beverly MA
Robert L. Powers - Topsfield MA

Assignee:

Eliza Corporation - Beverly MA

International Classification:

G10L 500

US Classification:

381 43

Abstract:

A phoneme estimator in a speech-recognition system includes energy detect circuitry for detecting the segments of a speech signal that should be analyzed for phoneme content. Speech-element processors then process the speech signal segments, calculating nonlinear (powers and products) representations of the segments. The nonlinear representation data is applied to speech-element modeling circuitry which reduces the data through speech element specific modeling. The reduced data are then subjected to further nonlinear processing. The results of the further nonlinear processing are again applied to speech-element modeling circuitry, producing phoneme isotype estimates. The phoneme isotype estimates are rearranged and consolidated, that is, the estimates are uniformly labeled and duplicate estimates are consolidated, forming estimates of words or phrases containing minimal numbers of phonemes. The estimates may then be compared with stored words or phrases to determine what was spoken.

US Patent:

50274082, Jun 25, 1991

Filed:

Apr 9, 1987

Appl. No.:

7/036380

Inventors:

John P. Kroeker - Beverly MA
Robert L. Powers - Topsfield MA

International Classification:

G10L 506

US Classification:

381 43

Abstract:

A phoneme estimator (12) in a speech-recognition system (10) includes trigger circuitry (18, 22) for identifying the segments of speech that should be analyzed for phoneme content. Speech-element processors (24, 26, and 28) calculate the likelihoods that currently received speech contains individual phonemes, but they operate only when the trigger circuitry identifies such segments. The computation-intensive processing for determining phoneme likelihoods is thus performed on only a small subset of the received speech segments. The accuracy of the speech-element processors (24, 26, and 28) is enhanced because these processors operate by recognition of patterns not only in elements of the data-reduced representations of the received speech but also in higher-ordered products of those elements; that is, these circuits employ non-linear modeling for phoneme identification.

US Patent:

45844852, Apr 22, 1986

Filed:

Aug 22, 1983

Appl. No.:

6/524994

Inventors:

Robert B. Powers - Norwell MA
Donald Adams - West Bridgewater MA
Angelo A. Marsocci - Duxbury MA

Assignee:

American District Telegraph Company - Jersey City NJ

International Classification:

G01N 1506

US Classification:

250574

Abstract:

An optical block for the exciter lamp and photocell includes a base with a first seat holding the lamp on a first optical axis and a second seat holding the cell on an intersecting optical axis. A cover with two light passages along the axes has a socket into which the base snap fits to confine the lamp and cell in their seats.