Robert D Ragland

US Patent:

8346339, Jan 1, 2013

Filed:

Mar 1, 2012

Appl. No.:

13/409263

Inventors:

Thomas F. Kordis - San Diego CA, US
Eric T. Johnson - Temecula CA, US
Philip C. Burke - Pala CA, US
Darrin J. Kent - Murrieta CA, US
Kevin M. Magrini - Temecula CA, US
Jeff A. Burke - Winchester CA, US
Robert Ryan Ragland - Temecula CA, US

Assignee:

Topera, Inc. - Scottsdale AZ

International Classification:

A61B 5/042

US Classification:

600374, 600393, 600509

Abstract:

A system for sensing multiple local electric voltages from endocardial surface of a heart, includes: an elongate tubular member; a plurality of flexible splines having proximal portions, distal portions and medial portions therein between; an anchor for securably affixing the proximal portions of the splines; a tip for securably affixing the distal portions of the splines; and a polymeric member including opposed a first open end and a second open end defining an open lumen therein between and an inner member surface and an outer member surface, wherein at least one of the plurality of flexible splines is at least partially disposed within the lumen of the polymeric member; a flexible electrode assembly strip with one or more exposed electrodes disposed on at least a portion of the outer surface of the polymeric member.

US Patent:

8364234, Jan 29, 2013

Filed:

Mar 1, 2012

Appl. No.:

13/409301

Inventors:

Thomas F. Kordis - San Diego CA, US
Ruchir Sehra - Scottsdale AZ, US
Eric T. Johnson - Temecula CA, US
Darrin J. Kent - Murrieta CA, US
Robert Ryan Ragland - Temecula CA, US

Assignee:

Topera, Inc. - Scottsdale AZ

International Classification:

A61B 5/042
A61B 18/14

US Classification:

600374, 600509, 600372, 606 41

Abstract:

A system a system for sensing multiple local electric voltages from endocardial surface of a heart, includes: a first elongate tubular member; a basket assembly including: a plurality of flexible splines for guiding a plurality of exposed electrodes, the splines having proximal portions, distal portions and medial portions therein between; a proximal anchor for securably affixing the proximal portions of the splines; the proximal anchor being secured at the distal end of the first elongate tubular member; a distal tip for securably affixing the distal portions of the splines wherein at least some of the splines in the radially expanded non-spherical shape contain a distal excurvate outward bend disposed at the distal portion of the spline at a location near to the distal tip of the basket assembly to bend the splines back towards the proximal anchor.

US Patent:

8364235, Jan 29, 2013

Filed:

Mar 1, 2012

Appl. No.:

13/409332

Inventors:

Thomas F. Kordis - San Diego CA, US
Eric T. Johnson - Temecula CA, US
Phillip C. Burke - Pala CA, US
Darrin J. Kent - Murrieta CA, US
Robert Ryan Ragland - Temecula CA, US

Assignee:

Topera, Inc. - Scottsdale AZ

International Classification:

A61B 5/042
A61B 18/14

US Classification:

600374, 600373, 600393, 600509, 606 41

Abstract:

A system for sensing multiple local electric voltages from endocardial surface of a heart, includes: a first elongate tubular member having a lumen, a proximal end and a distal end; and a basket assembly including: a plurality of flexible splines for guiding a plurality of exposed electrodes, the splines having proximal portions and distal portions; an anchor for securably affixing the proximal portions of the splines; the anchor being secured at the distal end of the first elongate tubular member; an encapsulated and filament-wrapped distal tip including an encapsulant and a filament for securably affixing the distal portions of the splines in a predetermined angular relationship at the distal tip; wherein the splines comprise a superelastic material; and wherein the basket assembly has a radially expanded non-cylindrical shape.

US Patent:

8504133, Aug 6, 2013

Filed:

Nov 28, 2012

Appl. No.:

13/687274

Inventors:

Eric T. Johnson - Temecula CA, US
Philip C. Burke - Pala CA, US
Darrin J. Kent - Murrieta CA, US
Kevin M. Magrini - Temecula CA, US
Jeff A. Burke - Winchester CA, US
Robert Ryan Ragland - Temecula CA, US

Assignee:

Topera, Inc. - Scottsdale AZ

International Classification:

A61B 5/042

US Classification:

600374, 600393, 600509

Abstract:

A system for sensing multiple local electric voltages from endocardial surface of a heart, includes: an elongate tubular member; a plurality of flexible splines having proximal portions, distal portions and medial portions therein between; an anchor for securably affixing the proximal portions of the splines; an atraumatic tip for securably affixing the distal portions of the splines; and a polymeric member including opposed a first open end and a second open end defining an open lumen therein between and an inner member surface and an outer member surface, wherein at least one of the plurality of flexible splines is at least partially disposed within the lumen of the polymeric member; a flexible electrode assembly strip with one or more exposed electrodes disposed on at least a portion of the outer surface of the polymeric member.

US Patent:

20130296930, Nov 7, 2013

Filed:

Oct 31, 2012

Appl. No.:

13/665160

Inventors:

Amir Belson - Los Altos CA, US
Eric Storne - Menlo Park CA, US
Eric T. Johnson - Temecula CA, US
Robert R. Ragland - Temecula CA, US
Phillip C. Burke - Pala CA, US
Luke Clauson - Redwood City CA, US

Assignee:

ZipLine Medical, Inc. - Los Altos CA

International Classification:

A61B 17/08

US Classification:

606216, 606215

Abstract:

Apparatus for closing a surgical incision comprise a base having left and right panels, a force distribution structure coupled to each panel, and a closure component which releasably attaches to the force distribution structure to draw the inner edges of the panels together in order to close adhered tissue edges. The force distribution structures allow the inner edges of the panels to expand while restraining expansion of the outer edges of the panels and limiting elongation of the lateral dimension of the panels. The incision closure appliance may be placed on skin or other tissue prior to forming the incision to be available to close said incision at the end of the surgical procedure.

US Patent:

20130331677, Dec 12, 2013

Filed:

Jun 28, 2013

Appl. No.:

13/929838

Inventors:

Eric T. Johnson - Temecula CA, US
Phillip C. Burke - Pala CA, US
Darrin J. Kent - Murrieta CA, US
Kevin M. Magrini - Temecula CA, US
Jeff A. Burke - Winchester CA, US
Robert Ryan Ragland - Temecula CA, US

Assignee:

Topera, Inc. - Scottsdale AZ

International Classification:

A61B 5/042

US Classification:

600375

Abstract:

A system for sensing monophasic action potentials from endocardial tissue of a heart, includes: a plurality of flexible splines; an anchor for securably affixing the proximal portions of the splines; a tip for securably affixing the distal portions of the splines; and a polymeric member including opposed a first open end and a second open end defining an open lumen therein between, where at least one of the plurality of flexible splines is at least partially disposed within the lumen of the polymeric member; a flexible electrode assembly strip with two or more exposed electrodes oppositely disposed on at least a portion of the outer surface of the polymeric member.

US Patent:

8323313, Dec 4, 2012

Filed:

Nov 1, 2011

Appl. No.:

13/286757

Inventors:

Amir Belson - Los Altos CA, US
Eric Storne - Menlo Park CA, US
Eric T. Johnson - Temecula CA, US
Robert R. Ragland - Temecula CA, US
Phillip C. Burke - Pala CA, US

Assignee:

ZipLine Medical, Inc. - Los Altos CA

International Classification:

A61B 17/08
A61D 1/00

US Classification:

606216

Abstract:

Apparatus for closing a surgical incision include a base having left and right panels, a force distribution structure coupled to each panel, and a closure component which releasably attaches to the force distribution structure to draw the inner edges of the panels together in order to close adhered tissue edges. The force distribution structures allow the inner edges of the panels to expand while restraining expansion of the outer edges of the panels and limiting elongation of the lateral dimension of the panels. The incision closure apparatus may be placed on skin or other tissue prior to forming the incision to be available to close said incision at the end of the surgical procedure.

US Patent:

20230001189, Jan 5, 2023

Filed:

Mar 23, 2022

Appl. No.:

17/656119

Inventors:

- San Diego CA, US
Douglas W. Brown - San Diego CA, US
Jean Campbell - Seattle WA, US
Richard J. Connolly - San Diego CA, US
Andy E. Denison - Temecula CA, US
Christopher S. Hayden - Winchester CA, US
Eric T. Johnson - Temecula CA, US
Robert H. Pierce - Seattle WA, US
Robert R. Ragland - Temecula CA, US

International Classification:

A61N 1/32

Abstract:

An adaptive control method for controlling EP pulse parameters during electroporation (EP) of cells or tissue using an EP system includes providing a system for adaptive control to optimize EP pulse parameters including EP pulse parameters, applying voltage and current excitation signals to the cells, obtaining data from the current and voltage measurements, and processing the data to separate the desirable data from the undesirable data, extracting relevant features from the desirable data, applying at least a portion of the relevant features to a trained diagnostic model, estimating EP pulsing parameters based on an outcome of the applied relevant features, where the initialized EP pulsing parameters are based on the trained model and the relevant features, to optimize the EP pulsing parameters, and applying, by the generator, a first EP pulse based on the first pulsing parameters.