Mark T. Bilodeau - Lansdale PA Mark E. Fraley - North Wales PA Randall W. Hungate - Lansdale PA Richard L. Kendall - Thousand Oaks CA Ruth Rutledge - Audubon PA Robert Rubino - Williamsville NY
Assignee:
Merck Co., Inc. - Rahway NJ
International Classification:
A61K 31505
US Classification:
514258
Abstract:
The present invention relates to compounds which inhibit tyrosine kinase enzymes, compositions which contain tyrosine kinase inhibiting compounds and methods of using tyrosine kinase inhibitors to treat tyrosine kinase-dependent diseases/conditions such as angiogenesis, cancer, atherosclerosis, diabetic retinopathy or autoimmune diseases, in mammals.
Mark E. Fraley - North Wales PA, US Scott R. Hambaugh - Philadelphia PA, US Robert S. Rubino - Williamsville NY, US Randall W. Hungate - Newbury Park CA, US
The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis, cancer, tumor growth, atherosclerosis, age related macular degeneration, diabetic retinopathy, macular edema, retinal ischemia, inflammatory diseases, and the like in mammals.
Mark T. Bilodeau - Lansdale PA Randall W. Hungate - Lansdale PA Richard L. Kendall - Doylestown PA Ruth Rutledge - Lansdale PA Kenneth A. Thomas - Chatham NJ Robert Rubino - Williamsville NY Mark E. Fraley - North Wales PA
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
A61K 31505 A61K 31535 C07D26530 C07D40300
US Classification:
514257
Abstract:
The present invention relates to compounds which inhibit tyrosine kinase enzymes, compositions which contain tyrosine kinase inhibiting compounds and methods of using tyrosine kinase inhibitors to treat tyrosine kinase-dependent diseases/conditions such as angiogenenesis, cancer, atherosclerosis, diabetic retinopathy or autoimmune diseases, in mammals.
Medical School UMDNJ New Jersey Medical School at Newark Graduated: 1991
Procedures:
Cesarean Section (C-Section) Colposcopy D & C Dilation and Curettage Delivery After Previous Caesarean Section Hysterectomy Myomectomy Ovarian Surgery Tubal Surgery Urinary Flow Tests Vaccine Administration Vaginal Delivery Vaginal Repair
Dr. Rubino graduated from the UMDNJ New Jersey Medical School at Newark in 1991. He works in Bayonne, NJ and 3 other locations and specializes in Obstetrics & Gynecology. Dr. Rubino is affiliated with Overlook Medical Center and Saint Barnabas Medical Center.