Robert Andrew Webster

US Patent:

6659934, Dec 9, 2003

Filed:

Dec 22, 1999

Appl. No.:

09/469510

Inventors:

James D. Hughett - Lawrenceville GA
Robert Michael Webster - Duluth GA
Douglas Layland Armstrong - Atlanta GA
Byron Lee Boylston - Woodstock GA
Gregg T. Juett - Clearwater FL
Richard A. Hillstead - Duluth GA
Andrew L. Lerohl - Hoschton GA
Mark Dehdashtian - Costa Mesa CA
Marvin A. Guiles - Stow MA

Assignee:

Novoste Corporation - Norcross GA

International Classification:

A61N 500

US Classification:

600 7, 600 3, 600 4

Abstract:

A transfer device usable in a system for intraluminal treatment of a selected site in a body of a patient in which the transfer device comprises an integral pump for pressurizing and circulating fluid through a fluid path defined by the transfer device and associated catheter. A removable fluid cartridge is provided including a reservoir from which fluid is drawn by the pump and into which fluid is returned after being circulated through the fluid path. The pump may be a peristaltic pump and the fluid cartridge may include an elongated fluid pick-up having an inlet through which fluid is introduced into the transfer device. The fluid pick-up is sized in length so that the inlet is always submerged in the fluid regardless of the orientation of the transfer device.

US Patent:

7066873, Jun 27, 2006

Filed:

Oct 27, 2003

Appl. No.:

10/694097

Inventors:

James D. Hughett - Lawrenceville GA, US
Robert Michael Webster - Duluth GA, US
Douglas Layland Armstrong - Atlanta GA, US
Byron Lee Boylston - Woodstock GA, US
Gregg T. Juett - Clearwater FL, US
Richard A. Hillstead - Duluth GA, US
Andrew L. Lerohl - Hoschton GA, US
Mark Dehdashtian - Costa Mesa CA, US
Marvin A. Guiles - Stow MA, US

Assignee:

Best Vascular, Inc. - Springfield VA

International Classification:

A61M 3/00
A61N 5/00

US Classification:

600 7, 604264

Abstract:

A transfer device usable in a system for intraluminal treatment of a selected site in a body of a patient in which the transfer device comprises an integral pump for pressurizing and circulating fluid through a fluid path defined by the transfer device and associated catheter. A removable fluid cartridge is provided including a reservoir from which fluid is drawn by the pump and into which fluid is returned after being circulated through the fluid path. The pump may be a peristaltic pump and the fluid cartridge may include an elongated fluid pick-up having an inlet through which fluid is introduced into the transfer device. The fluid pick-up is sized in length so that the inlet is always submerged in the fluid regardless of the orientation of the transfer device. A removable treatment cartridge having a lumen forming part of the fluid path may also be provided, and a storage sleeve for the treatment cartridge may be of a radiation-blocking material, such as quartz. Further, the treatment cartridge may have a memory for storing and indicating selected information about the treating element.

US Patent:

7311656, Dec 25, 2007

Filed:

Oct 27, 2003

Appl. No.:

10/694289

Inventors:

James D. Hughett - Lawrenceville GA, US
Robert Michael Webster - Duluth GA, US
Douglas Layland Armstrong - Atlanta GA, US
Byron Lee Boylston - Woodstock GA, US
Gregg T. Juett - Clearwater FL, US
Richard A. Hillstead - Duluth GA, US
Andrew L. Lerohl - Hoschton GA, US
Mark Dehdashtian - Costa Mesa CA, US
Marvin A. Guiles - Stow MA, US

Assignee:

Best Vascular, Inc. - Springfield VA

International Classification:

A61N 5/00

US Classification:

600 3

Abstract:

A transfer device usable in a system for intraluminal treatment of a selected site in a body of a patient in which the transfer device comprises an integral pump for pressurizing and circulating fluid through a fluid path defined by the transfer device and associated catheter. A removable fluid cartridge is provided including a reservoir from which fluid is drawn by the pump and into which fluid is returned after being circulated through the fluid path. The pump may be a peristaltic pump and the fluid cartridge may include an elongated fluid pick-up having an inlet through which fluid is introduced into the transfer device. The fluid pick-up is sized in length so that the inlet is always submerged in the fluid regardless of the orientation of the transfer device. A removable treatment cartridge having a lumen forming part of the fluid path may also be provided, and a storage sleeve for the treatment cartridge may be of a radiation-blocking material, such as quartz. Further, the treatment cartridge may have a memory for storing and indicating selected information about the treating element.

US Patent:

7850956, Dec 14, 2010

Filed:

Jan 22, 2004

Appl. No.:

10/763049

Inventors:

Harriet L. Robinson - Atlanta GA, US
Ellen F. Fynan - Sterling MA, US
Robert G. Webster - Memphis TN, US
Shan Lu - Franklin MA, US

Assignee:

University of Massachusetts Medical Center - Worcester MA
St. Jude Children's Research Hospital - Memphis TN

International Classification:

A61K 48/00
A61K 39/12

US Classification:

424 932, 514 44, 4241861

Abstract:

This invention relates to a method of immunizing a vertebrate, comprising introducing into the vertebrate a DNA transcription unit which comprises DNA encoding a desired antigen or antigens. The uptake of the DNA transcription unit by a host vertebrate results in the expression of the desired antigen or antigens, thereby eliciting humoral or cell-mediated immune responses or both humoral and cell-mediated responses. The elicited humoral and cell-mediated immune response can provide protection against infection by pathogenic agents, provide an anti-tumor response, or provide contraception. The host can be any vertebrate, avian or mammal, including humans.

US Patent:

8124101, Feb 28, 2012

Filed:

Jun 1, 2005

Appl. No.:

11/628292

Inventors:

Peter Palese - Leonia NJ, US
Adolfo Garcia-Sastre - New York NY, US
Richard J. Webby - Memphis TN, US
Juergen A. Richt - Ames IA, US
Robert G. Webster - Memphis TN, US
Kelly M. Lager - Colo IA, US

Assignee:

Mount Sinai School of Medicine - New York NY
St. Jude Children's Research Hospital - Memphis TN
The United States of America as represented by The Secretary of Agriculture - Washington DC

International Classification:

A61K 39/145
A61K 49/00

US Classification:

4242061, 4242091, 424 92

Abstract:

The present invention relates, in general, to attenuated swine influenza viruses having an impaired ability to antagonize the cellular interferon (IFN) response, and the use of such attenuated viruses in vaccine and pharmaceutical formulations. In particular, the invention relates to attenuated swine influenza viruses having modifications to a swine NS1 gene that diminish or eliminate the ability of the NS1 gene product to antagonize the cellular IFN response. These viruses replicate in vivo, but demonstrate decreased replication, virulence and increased attenuation, and therefore are well suited for use in live virus vaccines, and pharmaceutical formulations.

US Patent:

20040097777, May 20, 2004

Filed:

Oct 27, 2003

Appl. No.:

10/694032

Inventors:

James Hughett - Lawrenceville GA, US
Robert Webster - Duluth GA, US
Douglas Armstrong - Atlanta GA, US
Byron Boylston - Woodstock GA, US
Gregg Juett - Clearwater FL, US
Richard Hillstead - Duluth GA, US
Jack Griffis - Dacatur GA, US
Andrew Lerohl - Hoschton GA, US
Marvin Guiles - Stow MA, US

Assignee:

Novoste Corporation

International Classification:

A61N005/00

US Classification:

600/001000

Abstract:

A transfer device usable in a system for intraluminal treatment of a selected site in a body of a patient in which the transfer device comprises an integral pump for pressurizing and circulating fluid through a fluid path defined by the transfer device and associated catheter. A removable fluid cartridge is provided including a reservoir from which fluid is drawn by the pump and into which fluid is returned after being circulated through the fluid path. The pump may be a peristaltic pump and the fluid cartridge may include an elongated fluid pick-up having an inlet through which fluid is introduced into the transfer device. The fluid pick-up is sized in length so that the inlet is always submerged in the fluid regardless of the orientation of the transfer device. A removable treatment cartridge having a lumen forming part of the fluid path may also be provided, and a storage sleeve for the treatment cartridge may be of a radiation-blocking material, such as quartz. Further, the treatment cartridge may have a memory for storing and indicating selected information about the treating element.

US Patent:

20080004597, Jan 3, 2008

Filed:

Apr 6, 2007

Appl. No.:

11/784385

Inventors:

Omar Lattouf - Atlanta GA, US
Robert Webster - Orlando FL, US
Sarah Webster - Orlando FL, US
Sameer Shums - Lilbuen GA, US
Carribeth Ramey - Suwanee GA, US
Amin Rahme - Atlanta GA, US

International Classification:

A61M 31/00

US Classification:

604511000, 604101050, 604174000

Abstract:

Methods and devices for performing endocardiac treatments using an instrument port placed in the heart wall and an instrument guide which has a steerable tip and which is inserted through the instrument port, allows passage of an instrument therethrough into a heart chamber, and steers the functional tip of the instrument to the desired location for treatment.

US Patent:

20130034581, Feb 7, 2013

Filed:

Nov 23, 2011

Appl. No.:

13/304175

Inventors:

Peter Palese - Leonia NJ, US
Adolfo Garcia-Sastre - New York NY, US
Richard J. Webby - Memphis TN, US
Juergen A. Richt - Ames IA, US
Robert G. Webster - Memphis TN, US
Kelly M. Lager - Colo IA, US

International Classification:

C12N 7/04
C12N 5/073
A61K 39/12
C12N 5/07

US Classification:

4241991, 435236, 435350, 435349

Abstract:

The present invention relates, in general, to attenuated swine influenza viruses having an impaired ability to antagonize the cellular interferon (IFN) response, and the use of such attenuated viruses in vaccine and pharmaceutical formulations. In particular, the invention relates to attenuated swine influenza viruses having modifications to a swine NS1 gene that diminish or eliminate the ability of the NS1 gene product to antagonize the cellular IFN response. These viruses replicate in vivo, but demonstrate decreased replication, virulence and increased attenuation, and therefore are well suited for use in live virus vaccines, and pharmaceutical formulations.