Robert N Yee

US Patent:

7655799, Feb 2, 2010

Filed:

Nov 29, 2006

Appl. No.:

11/564744

Inventors:

Wenli Ma - Union City CA, US
Kevin T. Weber - Carmel IN, US
Robert M. Yee - San Francisco CA, US

Assignee:

Telik, Inc. - Palo Alto CA

International Classification:

A61K 31/435
C07F 9/572
C07F 9/576

US Classification:

546 22, 548413, 514277, 514 76

Abstract:

2-{[2-(Substituted amino)ethyl]sulfonyl}ethyl N,N,N′,N′-tetrakis(2-chloroethyl)-phosphorodiamidates, their preparation and intermediates in their preparation, pharmaceutical compositions containing them, and methods of treatment using them. The compounds are useful for treating cancer, alone and in combination with other anticancer therapies.

US Patent:

8150715, Apr 3, 2012

Filed:

Dec 30, 2008

Appl. No.:

12/346602

Inventors:

Robert Yee - San Francisco CA, US
Hersh Markusfeld - Mill Valley CA, US
Janet M. Soppe - Bedford TX, US

Assignee:

Strategic Health Management Corporation - Larkspur CA

International Classification:

G06Q 40/00

US Classification:

705 4, 705 2

Abstract:

Flexible, varying long term care insurance programs for use as parts of combination long term care products are generated. Input variables such as issue age, targeted present value and year-to-year premium relationship are supplied, as are some members of a set of process variables. A non-supplied process variable is calculated based on the input variables and the supplied process variables. An insurance program based on the supplied variables and the calculated process variable is then generated, such that the premium schedule increases (or alternatively, increases and decreases) over time to at least one leveling point, at which premiums become level. A combination long term care product is produced by coupling the generated insurance program with a life insurance program or annuity.

US Patent:

20050026929, Feb 3, 2005

Filed:

Apr 23, 2003

Appl. No.:

10/421372

Inventors:

Sui Cai - San Diego CA, US
Ben Cebon - Kew, AU
Joane Litvak - Oakland CA, US
Keith Pararajasingham - So. San Francisco CA, US
Emma Shelton - Menlo Park CA, US
Jeffrey Spencer - So. San Francisco CA, US
David Sperandio - Mountain View CA, US
Paul Sprengeler - El Granada CA, US
Vincent Tai - So. San Francisco CA, US
Robert Yee - San Francisco CA, US

Assignee:

AXYS PHARMACEUTICALS, INC. - So. San Francisco CA
CYTOVIA, INC. - San Diego CA

International Classification:

C07D417/02
C07D413/02
C 07D 4 3/02
A61K031/496
A61K031/454
A61K031/422
A61K031/427

US Classification:

514254020, 514326000, 514365000, 514374000, 514383000, 514396000, 544369000, 544370000, 546208000, 546209000

Abstract:

The present invention related to certain phenyl derivatives that are activators of caspases and inducers of apoptosis, pharmaceutical composition comprising these compounds and method of treating cancer utilizing these compounds.

US Patent:

20080125397, May 29, 2008

Filed:

Nov 28, 2006

Appl. No.:

11/564091

Inventors:

Stella K. Lui - Pacifica CA, US
Wenli Ma - Mountain View CA, US
Robert M. Yee - San Francisco CA, US

International Classification:

A61K 31/675
A61P 35/04
C07F 9/06

US Classification:

514 89, 546 22, 564 12

Abstract:

2-({2-Oxo-2-[(pyridin-3-ylmethyl)amino]ethyl}sulfonyl)ethyl N,N,N′,N′-tetrakis(2-chloroethyl)phosphorodiamidate and its acid addition salts, especially in solid form, their preparation and intermediates in their preparation, formulations containing them, and methods of treatment using them. The compounds are useful for treating cancer, alone and in combination with other anticancer therapies.

US Patent:

20130132121, May 23, 2013

Filed:

Mar 24, 2006

Appl. No.:

11/389416

Inventors:

Robert Yee - San Francisco CA, US

International Classification:

G06Q 40/08
G06Q 50/22

US Classification:

705 4

Abstract:

Flexible, varying critical illness insurance premium schedules are determined. Input variables such as issue age, targeted present value and year-to-year premium relationship are supplied, as are some members of a set of process variables. A non-supplied process variable is calculated based on the input variables and the supplied process variables. A premium schedule based on the supplied variables and the calculated process variable is then determined, such that the premium schedule increases (or alternatively decreases) over time to at least one leveling point, at which premiums become level.

US Patent:

20130132123, May 23, 2013

Filed:

Apr 2, 2012

Appl. No.:

13/437654

Inventors:

Robert Yee - San Francisco CA, US

International Classification:

G06Q 40/08

US Classification:

705 4

Abstract:

Flexible, varying long term care insurance programs are determined. Input variables such as issue age, targeted present value and year-to-year premium relationship are supplied, as are some members of a set of process variables. A non-supplied process variable is calculated based on the input variables and the supplied process variables. An insurance program based on the supplied variables and the calculated process variable is then determined, such that the premium schedule increases (or alternatively, decreases) over time to at least one leveling point, at which premiums become level.

US Patent:

58094571, Sep 15, 1998

Filed:

Mar 8, 1996

Appl. No.:

8/614784

Inventors:

Robert Yee - Mountain View CA
Fred Robbins - Santa Clara CA

Assignee:

The United States of America as represented by the Administrator of the
National Aeronautics and Space Administration - Washington DC

International Classification:

G05B 1918
H01Q 300

US Classification:

701220

Abstract:

An inertial pointing and control system and method for pointing to a designated target with known coordinates from a platform, to provide accurate position, steering, and command information. The system continuously receives GPS signals and corrects Inertial Navigation System (INS) dead reckoning or drift errors. An INS is mounted directly on a pointing instrument rather than in a remote location on the platform for monitoring the terrestrial position and instrument attitude, and for pointing the instrument at designated celestial targets or ground based landmarks. As a result, the pointing instrument and the INS move independently in inertial space from the platform since the INS is decoupled from the platform. Another important characteristic of the present system is that selected INS measurements are combined with predefined coordinate transformation equations and control logic algorithms under computer control in order to generate inertial pointing commands to the pointing instrument. More specifically, the computer calculates the desired instrument angles (Phi, Theta, Psi), which are then compared to the Euler angles measured by the instrument-mounted INS, and forms the pointing command error angles as a result of the compared difference.