Gregg R. Dieckmann - Plano TX, US Alfonzo Ortiz-Acevedo - El Paso TX, US Ray Baughman - Dallas TX, US Alan B. Dalton - Shamley Green, GB Rockford K. Draper - Plano TX, US Inga H. Musselman - Dallas TX, US
Assignee:
Board of Regents, The University of Texas System - Austin TX
The present invention includes compositions and methods for the isolation, separation and chelation of Carbon Nanotubes (CNTs) using a cyclizable peptide.
Method For Measuring Carbon Nanotubes Taken-Up By A Plurality Of Living Cells
Rockford K. Draper - Plano TX, US Paul Pantano - Plano TX, US Carole Mikoryak - Richardson TX, US
Assignee:
Board of Regents, University of Texas System - Austin TX
International Classification:
G01N 27/447
US Classification:
204456, 204466
Abstract:
The present invention provides methods, apparatuses and kits for determining the presence and the concentration of nanoparticles in a given area, solution or region via cellular uptake and/or adsorption monitored through laboratory equipment. For example, the present invention provides a method of quantifying one or more nanoparticles by incubating a nanoparticle solution comprising one or more nanoparticles with one or more cells; isolating the one or more cells; lysing the one or more cells to release a cell lysate; separating the cell lysate electrophoretically on a gel; digitizing the gel to form a gel image; quantifying the nanoparticle intensity in the gel image; and correlating the nanoparticle intensity to a cell-associated nanoparticle concentration.
Methods And Materials For Extra And Intracellular Delivery Of Carbon Nanotubes
Tanja Kmecko - Plano TX, US Gareth Hughes - Irving TX, US Rockford K Draper - Plano TX, US Robert M. Burgess - Garland TX, US Austin David-Edmiston Swafford - Richardson TX, US
Assignee:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM - Austin TX MEDICAL NANOTECHNOLOGIES, INC. - Richardson TX
The present invention includes compositions and methods to deliver carbon nanostructures that include agents for delivery to cells, wherein the carbon nanostructure and the agent are made soluble by coating the carbon nanostructure with one or more polymers, e.g., low band gap conductive polymers.
Methods And Compositions For Using Membrane-Penetrating Proteins To Carry Materials Across Cell Membranes
Board of Regents, The University of Texas Systems - Austin TX
International Classification:
A61K 3944 C12N 510 C07K 1702
US Classification:
4242821
Abstract:
The present invention provides methods and compositions delivery of agents into the cytoplasm of cells. Particularly, it concerns the use of membrane-penetrating toxin proteins to deliver drugs to the cytoplasm of target cells.