Rodolfo Rodriguez

US Patent:

20090233329, Sep 17, 2009

Filed:

Mar 26, 2007

Appl. No.:

12/294037

Inventors:

Rodolfo R. Rodriguez - Durham NC, US
Charles F. Galanaugh - West Milford NJ, US

International Classification:

C12Q 1/06
C12M 1/34

US Classification:

435 39, 4352871

Abstract:

The present invention relates to a device and method for the detection of mastitis or other disease from a body fluid of a mammal for example from cow's milk. The device and method relates to a wedge microfluidic chamber for using a minimal amount of fluid and being able to use the device to observe leukocytes in a mono-layer for the purpose of disease detection, cell counts or the like.

US Patent:

20140009596, Jan 9, 2014

Filed:

Jun 27, 2013

Appl. No.:

13/928741

Inventors:

David A. Calderwood - Chapel Hill NC, US
Tobias M. Heineck - Durham NC, US
David Newcomb - Morrisville NC, US
Chris Paul - Hillsborough NC, US
Jasper N. Pollard - Durham NC, US
Rodolfo R. Rodriguez - Cary NC, US
Demetris Young - Durham NC, US

International Classification:

G06T 7/00
G06F 1/20
G02B 21/26
G02B 21/00

US Classification:

348 79, 359368, 36167954, 359392

Abstract:

An automated microscope apparatus, comprises an outer housing having an external wall; optionally but preferably an internal wall in said housing, and configured to form a first compartment and a separate second compartment in said outer housing; a microscope assembly in said housing, preferably in said first compartment; and a microprocessor in said housing, preferably in said second compartment; and optionally but preferably a heat sink mounted on said housing external wall, preferably adjacent said second compartment, with said microprocessor thermally coupled to said heat sink and operatively associated with said microscope assembly.

US Patent:

20180172676, Jun 21, 2018

Filed:

Nov 13, 2017

Appl. No.:

15/810534

Inventors:

- Morrisville NC, US
David A. Calderwood - Chapel Hill NC, US
Tobias M. Heineck - Durham NC, US
David Newcomb - Morrisville NC, US
Chris Paul - Hillsborough NC, US
Jaspar N. Pollard - Durham NC, US
Rodolfo R. Rodriguez - Cary NC, US
Demetris Young - Durham NC, US

International Classification:

G01N 33/50
G02B 21/00
G06T 7/00
G02B 21/26
G06F 1/20

Abstract:

An automated microscope apparatus, comprises an outer housing having an external wall; optionally but preferably an internal wall in said housing, and configured to form a first compartment and a separate second compartment in said outer housing; a microscope assembly in said housing, preferably in said first compartment; and a microprocessor in said housing, preferably in said second compartment; and optionally but preferably a heat sink mounted on said housing external wall, preferably adjacent said second compartment, with said microprocessor thermally coupled to said heat sink and operatively associated with said microscope assembly.

US Patent:

20150072880, Mar 12, 2015

Filed:

May 9, 2013

Appl. No.:

14/239660

Inventors:

David A. Calderwood - Chapel Hill NC, US
Rodolfo R. Rodriguez - Cary NC, US

International Classification:

G01N 33/543
G01N 33/569

US Classification:

506 9, 422 69, 506 18, 4352872, 436501, 435 732, 435 733, 435 5, 435 737, 435 735, 435 734, 435 731, 435 736

Abstract:

A device for detecting at least one analyte generally comprises (i) a support having a chamber for receiving a biological fluid therein, wherein said chamber is an elongate chamber having a length axis; (ii) a carrier or agitator in said elongate chamber, said carrier or agitator having opposite end portions and a side portion, the carrier or agitator dimensioned to travel in said chamber along said length axis and/or permit said liquid sample to flow in the chamber therearound, either (or both) thereby agitating the liquid sample; and (iii) at least one anti-analyte antibody coupled to either the carrier and/or the chamber side wall. Methods of using the device are also described.

US Patent:

20140315283, Oct 23, 2014

Filed:

May 9, 2013

Appl. No.:

14/239894

Inventors:

David A. Calderwood - Chapel Hill NC, US
Rodolfo Rodriguez - Cary NC, US
Demetris Young - Durham NC, US
Jasper N. Pollard - Durham NC, US
Robert L. Cheek - Mebane NC, US
Duane Olsen - Hillsborough NC, US
John Groelke - Raleigh NC, US
Reha Azizoglu - Morrisville NC, US
Mitch Hockett - Raleigh NC, US
David Newcomb - Morrisville NC, US
Tobias M. Heineck - Durham NC, US
Joy Parr Drach - Pontiac IL, US

International Classification:

G01N 33/569

US Classification:

4352872

Abstract:

A sample cartridge () for microscopic imaging of a biological sample comprises a body having an end portion () and a pair of generally parallel opposing side edge portions (), a locking edge portion () formed on the body; a carrier removably connected to or permanently connected to the body; and at least one anti-analyte antibody coupled to either the carrier or to the chamber () side wall portion (e.g., at the surface to be imaged, or supporting the sample to be imaged). An XYZ stage () for receiving such a cartridge () is also described.

US Patent:

20140233098, Aug 21, 2014

Filed:

Jul 2, 2013

Appl. No.:

14/239208

Inventors:

- Durham NC, US
David A. Calderwood - Chapel Hill NC, US
Tobias M. Heineck - Durham NC, US
David Newcomb - Morrisville NC, US
Chris Paul - Hillsborough NC, US
Jasper N. Pollard - Durham NC, US
Rodolfo R. Rodriguez - Cary NC, US
Demetris Young - Durham NC, US

International Classification:

G02B 21/26
G02B 21/28
G01N 33/487

US Classification:

359392, 359395

Abstract:

An automated microscope apparatus comprises an outer housing having an external wall; optionally but preferably an internal wall in the housing configured to form a first compartment and a separate second compartment in the outer housing; a microscope assembly in the housing (preferably in the first compartment); a microprocessor in the housing (preferably in the second compartment), and (optionally but preferably) a heat sink mounted on the housing external wall, preferably adjacent the second compartment, with the microprocessor thermally coupled to said heat sink and operatively associated with the microscope assembly. Systems and methods employing the same are also described, along with component parts thereof.