Roger Dale Calhoon

US Patent:

57598282, Jun 2, 1998

Filed:

Sep 20, 1994

Appl. No.:

8/309512

Inventors:

Rony Tal - Richmond CA
David H. Gelfand - Oakland CA
Roger D. Calhoon - San Diego CA
Arie Ben-Bassat - Gainesville FL
Moshe Benziman - Jerusalem, IL
Hing Cheung Wong - San Ramon CA

Assignee:

Weyerhaeuser - Federal Way WA

International Classification:

C12N 1563
C12N 1570
C12N 1574
C12P 104

US Classification:

4351723

Abstract:

The present invention provides the nucleotide sequences of Acetobacter operons, cdg operons encoding genes for the biosynthesis and degradation of cyclic diguanosine monophosphate (c-di-GMP). Specifically, the nucleotide sequences and deduced amino acid sequences of 3 phosphodiesterases isozymes, 3 diguanylate cyclase isozymes, and 2 polypeptides of unidentified function are provided. Also provided for are various strains of microorganisms, including Acetobacter cells genetically manipulated so as to produce elevated and/or reduced levels of one or more cdg operon encoded proteins.

US Patent:

52682749, Dec 7, 1993

Filed:

Apr 22, 1991

Appl. No.:

7/689008

Inventors:

Arie Ben-Bassat - Walnut Creek CA
Roger D. Calhoon - Concord CA
Anna L. Fear - Oakland CA
David H. Gelfand - Oakland CA
James H. Meade - Pinole CA
Rony Tal - Richmond CA
Hing Wong - San Ramon CA
Moshe Benziman - Jerusalem, IL

Assignee:

Cetus Corporation - Emeryville CA

International Classification:

C12N 1500
C12N 1554
C12N 1574
C12P 1904

US Classification:

435 691

Abstract:

Nucleic acid sequences encoding the bacterial cellulose synthase operon derived from Acetobacter are disclosed. Methods for isolating the genes, vectors containing the genes, and transformed hosts useful for the expression of recombinant bacterial cellulose synthase or production of cellulose are also described.