Michael Goodman - Rancho Santa Fe CA William Weigle - Del Mar CA Stanley Bell - Narberth PA Robert Chen - Belle Mead NJ Roland K. Robins - Irvine CA William J. Hennen - Bryan TX
International Classification:
A61K 3170 C08B 3100
US Classification:
514 45
Abstract:
7,8-Disubstituted guanosine nucleoside derivatives are found to be potent immune response enhancing agents in human and animal cells. 7-Substituents are hydrocarbyl radicals having a length greater than ethyl and less than about decyl. 8-Substituents are. dbd. O,. dbd. S,. dbd. Se and. dbd. NCN. Compositions and methods of use are also disclosed.
Isbn (Books And Publications)
Chemistry and Biology of Nucleosides and Nucleotides