Ronald M Hopkins

US Patent:

6368613, Apr 9, 2002

Filed:

Dec 21, 1998

Appl. No.:

09/217491

Inventors:

Mark A. Walters - San Diego CA
Ronald M. Hopkins - Escondido CA
David H. Klein - Carlsbad CA

Assignee:

Alliance Pharmaceutical Corp. - San Diego CA

International Classification:

A61K 910

US Classification:

424423, 514825

Abstract:

Methods for the diagnosis and treatment of articular disorders comprising the use of fluorocarbons are disclosed. The methods provide for the introduction of a fluorocarbon into an articular region to replace or augment natural synovial fluid. The introduced fluorocarbons, which may be in various forms including liquids, gels or emulsions, provide articular lubrication and cushioning which is effective for the treatment of disorders such as osteoarthritis and rheumatoid arthritis. Additionally, the methods of the present invention may be used to provide high resolution articular images, reduce articular inflammation and introduce bioactive agents to the articular region.

US Patent:

RE38081, Apr 15, 2003

Filed:

Feb 2, 2001

Appl. No.:

09/776144

Inventors:

Nicholas Simon Faithfull - La Jolla CA 92037
Peter E. Keipert - San Diego CA 92130
Duane J. Roth - La Jolla CA 92037
Ronald M. Hopkins - Escondido CA 92029

International Classification:

A61M 3700

US Classification:

604 401, 604 614

Abstract:

A method for hemodiluting a patient is disclosed which includes the steps of administering a biocompatible oxygen carrier in conjunction with surgery or organ ischemia or infarct while assessing the patients PvO or other oxygenation indices, and administering to the patient additional oxygen carrier or autologous blood in response to the PvO value if necessary to maintain the PvO at or above the desired level.

US Patent:

20020077368, Jun 20, 2002

Filed:

Nov 12, 2001

Appl. No.:

10/008257

Inventors:

Mark Walters - San Diego CA, US
Ronald Hopkins - Escondido CA, US
David Klein - Carlsbad CA, US

International Classification:

A61K031/02

US Classification:

514/759000

Abstract:

Methods for the diagnosis and treatment of articular disorders comprising the use of fluorocarbons are disclosed. The methods provide for the introduction of a fluorocarbon into an articular region to replace or augment natural synovial fluid. The introduced fluorocarbons, which may be in various forms including liquids, gels or emulsions, provide articular lubrication and cushioning which is effective for the treatment of disorders such as osteoarthritis and rheumatoid arthritis. Additionally, the methods of the present invention may be used to provide high resolution articular images, reduce articular inflammation and introduce bioactive agents to the articular region.

US Patent:

58657843, Feb 2, 1999

Filed:

Jun 7, 1995

Appl. No.:

8/484166

Inventors:

Nicholas Simon Faithfull - La Jolla CA
Peter E. Keipert - San Diego CA
Duane J. Roth - La Jolla CA
Ronald M. Hopkins - Escondido CA

Assignee:

Alliance Pharmaceutical Corp. - San Diego CA

International Classification:

A61K 4700

US Classification:

604 4

Abstract:

A method for hemodiluting a patient is disclosed which includes the steps of administering a biocompatible oxygen carrier in conjunction with surgery or organ ischemia or infarct while assessing the patient's PvO. sub. 2 or other oxygenation indices, and administering to the patient additional oxygen carrier or autologous blood in response to the PvO. sub. 2 value if necessary to maintain the PvO. sub. 2 at or above the desired level.

US Patent:

58611754, Jan 19, 1999

Filed:

Mar 15, 1996

Appl. No.:

8/616260

Inventors:

Mark A. Walters - San Diego CA
Ronald M. Hopkins - Escondido CA
David H. Klein - Carlsbad CA

Assignee:

Alliance Pharmaceutical Corp. - San Diego CA

International Classification:

A61K 910
A61K 31755

US Classification:

424486

Abstract:

Methods for the diagnosis and treatment of articular disorders comprising the use of fluorocarbons are disclosed. The methods provide for the introduction of a fluorocarbon into an articular region to replace or augment natural synovial fluid. The introduced fluorocarbons, which may be in various forms including liquids, gels or emulsions, provide articular lubrication and cushioning which is effective for the treatment of disorders such as osteoarthritis and rheumatoid arthritis. Additionally, the methods of the present invention may be used to provide high resolution articular images, reduce articular inflammation and introduce bioactive agents to the articular region.

US Patent:

60077743, Dec 28, 1999

Filed:

Jun 18, 1998

Appl. No.:

9/099731

Inventors:

Nicholas Simon Faithfull - La Jolla CA
Peter E. Keipert - San Diego CA
Duane J. Roth - La Jolla CA
Ronald M. Hopkins - Escondido CA

Assignee:

Alliance Pharmaceutical Corp. - San Diego CA

International Classification:

A61M 114
A61M 3700

US Classification:

422 44

Abstract:

A method for treating conditions associated with ischemia or infarct is disclosed which includes the steps of administering a biocompatible non-blood oxygen carrier while monitoring one or more oxygenation indices to maintain oxygenation of the patient's tissues at or above a predetermined level.