Ronald M Paul

US Patent:

20130203109, Aug 8, 2013

Filed:

Jan 25, 2013

Appl. No.:

13/750686

Inventors:

Russell Myers - Richmond IL, US
Ronald Paul - Clancy MT, US
Audra Rasmussen - Kenosha WI, US
Kate Taylor - Melbourne, AU

Assignee:

Leica Biosystems Richmond, Inc. - Richmond IL

International Classification:

G01N 1/30

US Classification:

435 405

Abstract:

The present invention provide for solutions of a defined composition useful in a staining protocol, such as a hematoxylin and eosin staining protocol, when used at certain points of the staining protocol. The formulations of these defined solutions are such that carry-over of the solutions will not negatively impact, or preferably, will stabilize or favorably modify staining reagent solutions coming in contact with the solutions. In certain embodiments of the invention, solutions are buffered to maintain a specific pH that when carried-over—such as carried-over into hematoxylin—will not significantly influence the pH of the next staining reagent.

US Patent:

20160327458, Nov 10, 2016

Filed:

Jul 22, 2016

Appl. No.:

15/216910

Inventors:

- Richmond IL, US
Russell Myers - Richmond IL, US
Ronald Paul - Clancy MT, US
Audra Rasmussen - Kenosha WI, US
Kate Taylor - Melbourne, AU

International Classification:

G01N 1/30
G01N 33/68

Abstract:

The present invention provide for solutions of a defined composition useful in a staining protocol, such as a hematoxylin and eosin staining protocol, when used at certain points of the staining protocol. The formulations of these defined solutions are such that carry-over of the solutions will not negatively impact, or preferably, will stabilize or favorably modify staining reagent solutions coming in contact with the solutions. In certain embodiments of the invention, solutions are buffered to maintain a specific pH that when carried-over—such as carried-over into hematoxylin—will not significantly influence the pH of the next staining reagent.

US Patent:

20140242634, Aug 28, 2014

Filed:

May 2, 2014

Appl. No.:

14/268274

Inventors:

- Richmond IL, US
Russell Myers - Richmond IL, US
Ronald Paul - Clancy MT, US
Audra Rasmussen - Kenosha WI, US
Kate Taylor - Melbourne, AU

International Classification:

G01N 1/30

US Classification:

435 4052

Abstract:

The present invention provide for solutions of a defined composition useful in a staining protocol, such as a hematoxylin and eosin staining protocol, when used at certain points of the staining protocol. The formulations of these defined solutions are such that carry-over of the solutions will not negatively impact, or preferably, will stabilize or favorably modify staining reagent solutions coming in contact with the solutions. In certain embodiments of the invention, solutions are buffered to maintain a specific pH that when carried-over—such as carried-over into hematoxylin—will not significantly influence the pH of the next staining reagent.