Ronald L Ross

US Patent:

6395479, May 28, 2002

Filed:

Jan 22, 1999

Appl. No.:

09/235538

Inventors:

Juergen K. V. Reichardt - Altadena CA
Gerhard A. Coetzee - La Canada CA
Brian E. Henderson - San Marino CA
Nick Makridakis - Glendale CA
Ronald Ross - Pasadena CA

Assignee:

University of Southern California - Los Angeles CA

International Classification:

C12Q 168

US Classification:

435 6, 435 911, 536 231

Abstract:

This present invention identifies mutations in several androgen-metabolic genes (SRD5A2, CYP17, HSD3B2, and HSD17B3) and methods of using such mutations in the diagnosis and treatment of inheritable prostate cancer susceptibility. Isolation of genomic DNA of various racial/ethnic populations followed by SSCP scanning and direct PCR sequencing of the aberrant SSCP (single-strand conformation dependent DNA polymorphism) patterns allows for identification of the disclosed polymorphisms. Screening for the disclosed mutations establishes a differential distribution among various racial/ethnic groups as well as altered in vivo enzyme activity that parallels prostate cancer risk.

US Patent:

41631943, Jul 31, 1979

Filed:

Jul 22, 1977

Appl. No.:

5/818122

Inventors:

Ronald G. Ross - La Canada CA

Assignee:

California Institute of Technology - Pasadena CA

International Classification:

G01N 2742

US Classification:

324 295

Abstract:

A meter is disclosed for measuring the voltage, current, and power (VIP) parameters of a photovoltaic solar array, or array module, under sunlight operating conditions utilizing a variable load connected across the array and controlled by a voltage regulator which responds to the difference between the output voltage of the array and a programmed test voltage from a source which generates a single ramp voltage for measuring and recording current as a function of voltage, repeated ramp voltages at a high rate for peak output measurements or a DC voltage for VIP measurements at selected points on the I-V characteristic curve of the array. The voltage signal from a current sensing element, such as a shunt resistor in series with the variable load, is compared with the output current of a reference solar cell to provide a normalizing signal to be added to the signal from the current-sensing element in order to provide a record of array current as a function of array voltage, i. e. , for all load conditions from short circuit to open circuit. As the normalized current is thus measured, an analog multiplier multiplies the array voltage and normalized current to provide a measurement of power.