Ronald Bradford Terry

US Patent:

7250153, Jul 31, 2007

Filed:

Nov 5, 2003

Appl. No.:

10/701586

Inventors:

Milos Sovak - Rancho Santa Fe CA, US
Allen L. Seligson - Ramona CA, US
Ronald C. Terry - San Diego CA, US

Assignee:

Biophysica Research, Inc. - La Jolla CA

International Classification:

A61K 49/04

US Classification:

424 9452

Abstract:

This invention comprises new formulations of radiographic contrast media including dimeric non-ionic media, with an organic amine and a carboxylic acid. Formulations of this invention increase the biological tolerance of such media, thereby increasing their safety.

US Patent:

20030199581, Oct 23, 2003

Filed:

Mar 12, 2003

Appl. No.:

10/387024

Inventors:

Allen Seligson - Ramona CA, US
Ronald Terry - San Diego CA, US
Milos Sovak - La Jolla CA, US
Daniel Alexander - Modrany, CZ

International Classification:

C07C067/02
A61K031/225

US Classification:

514/548000, 560/256000

Abstract:

The biological activity of naturally occurring boswellic acids in specific plant extracts is enhanced by their peracetylation, preferably followed by silica gel treatment, or by peracetylation and mild oxidation to increase the ratio of 3--acetyl-11-keto--boswellic acid to -boswellic acid, 3--acetyl--boswellic acid and 11-keto--boswellic acid. The enriched compositions compared to the commercial extracts have enhanced biological activity toward a variety of proliferative and/or inflammatory afflictions in mammalian hosts and demonstrate synergism with other phytochemicals.

US Patent:

54878853, Jan 30, 1996

Filed:

Dec 9, 1993

Appl. No.:

8/164881

Inventors:

Milos Sovak - La Jolla CA
Ronald C. Terry - San Diego CA
James G. Douglass - San Diego CA
Farid Bakir - Del Mar CA

Assignee:

Biophysica, Inc. - La Jolla CA

International Classification:

A61K 3178
A61K 742

US Classification:

424 59

Abstract:

Novel polymeric compositions and their intermediates are provided, providing for broad range protection from ultraviolet radiation. Acryl polymers comprising at least two different ultraviolet absorbing moieties having different light absorbing ranges are employed in conjunction with another hydrophilic monomer to provide sunscreen formulations for invisibility, and enhanced protection, without deleterious effects in the dermis.

US Patent:

57419248, Apr 21, 1998

Filed:

Jun 14, 1995

Appl. No.:

8/490316

Inventors:

Milos Sovak - La Jolla CA
Ronald Calvin Terry - San Diego CA
James Gordon Douglass - San Diego CA
Farid Bakir - Del Mar CA

Assignee:

Biophysica Inc. - La Jolla CA

International Classification:

C07C22900
C07C 4936
A61K 742

US Classification:

560 43

Abstract:

Novel polymeric compositions and their intermediates are provided, providing for broad range protection from ultraviolet radiation. Acryl polymers comprising at least two different ultraviolet absorbing moieties having different light absorbing ranges are employed in conjunction with another hydrophilic monomer to provide sunscreen formulations for invisibility, and enhanced protection, without deleterious effects in the dermis.

US Patent:

61239283, Sep 26, 2000

Filed:

Jul 21, 1998

Appl. No.:

9/119836

Inventors:

Milos Sovak - La Jolla CA
Ronald C. Terry - San Diego CA
James G. Douglass - San Diego CA
Farid Bakir - Del Mar CA
Jason Brown - Encinitas CA
Peter Cugley - San Diego CA

Assignee:

Biophysica, Inc. - La Jolla CA

International Classification:

A61K 742
A61K 744
A61K 700
A61K 3178

US Classification:

424 59

Abstract:

Novel polymeric biologically inert compositions and their intermediates, as well as sunscreen formulations comprising them and making them invisible, are provided for broad range protection from ultraviolet radiation. Acryl polymers comprising at least two different ultraviolet absorbing moieties having different light absorbing ranges are employed in conjunction with other monomers to provide sunscreen polymers as microparticles. The polymer microparticles, once imbibed with carrier compounds, change the refractive index, thus providing invisible sunscreen formulations which offer enhanced protection without adverse physiological effects.