Samuel Xin Li

US Patent:

7781209, Aug 24, 2010

Filed:

Sep 29, 2006

Appl. No.:

11/529826

Inventors:

Helena S. Mancebo - Fremont CA, US
Samuel X. Li - Redmond WA, US
Jianfu L. Wang - Union City CA, US

Assignee:

Multispan, Inc. - Hayward CA

International Classification:

C12N 15/00
C12N 1/20
C12N 5/00
C12N 5/02
C12N 15/74
C12P 21/06
C07K 1/00
C07K 14/00
C07K 17/00

US Classification:

4353201, 435 691, 4352523, 435325, 435471, 530350

Abstract:

The present invention provides expression vectors that facilitate high levels of expression of GPCR proteins. Encompassed by the invention are methods and compositions for recombinant cell lines expressing GPCR proteins with the aid of the expression vectors of the instant invention. The recombinant cell lines of the instant invention express GPCR proteins at levels of at least about 150,000 copies of the protein per cell. The present invention also provides methods and compositions for raising antibodies against GPCR proteins using the high expressing recombinant cells of the instant invention.

US Patent:

8178346, May 15, 2012

Filed:

Jun 22, 2010

Appl. No.:

12/820987

Inventors:

Helena S. Mancebo - Fremont CA, US
Samuel X. Li - Redmond WA, US
Jianfu L. Wang - Union City CA, US

Assignee:

Multispan, Inc. - Hayward CA

International Classification:

C12N 15/00
C12N 1/20
C12N 5/00
C12N 5/02
C12N 15/74
C12P 21/06
C07K 1/00
C07K 14/00
C07K 17/00

US Classification:

4353201, 435 691, 4352523, 435325, 435471, 530350

Abstract:

The present invention provides expression vectors that facilitate high levels of expression of GPCR proteins. Encompassed by the invention are methods and compositions for recombinant cell lines expressing GPCR proteins with the aid of the expression vectors of the instant invention. The recombinant cell lines of the instant invention express GPCR proteins at levels of at least about 150,000 copies of the protein per cell. The present invention also provides methods and compositions for raising antibodies against GPCR proteins using the high expressing recombinant cells of the instant invention.

US Patent:

8296398, Oct 23, 2012

Filed:

Apr 28, 2009

Appl. No.:

12/431345

Inventors:

Francesco Lacapra - Sunnyvale CA, US
Peter Wallace Steele - Campbell CA, US
Bruno Sartirana - Loomis CA, US
Ernest Ying Sue Hua - Cupertino CA, US
I Chung Joseph Lin - San Jose CA, US
Samuel Sui-Lun Li - Pleasanton CA, US
Nathanael John Diller - San Francisco CA, US
Thomas Reynold Ramsdell - Palos Verdes CA, US
Don Nguyen - Tracy CA, US
Kyle Dinh Tran - San Jose CA, US

Assignee:

Overland Storage, Inc. - San Diego CA

International Classification:

G06F 15/16

US Classification:

709219, 209203, 209217, 209226

Abstract:

Peer-to-peer redundant file server system and methods include clients that determine a target storage provider to contact for a particular storage transaction based on a pathname provided by the filesystem and a predetermined scheme such as a hash function applied to a portion of the pathname. Servers use the same scheme to determine where to store relevant file information so that the clients can locate the file information. The target storage provider may store the file itself and/or may store metadata that identifies one or more other storage providers where the file is stored. A file may be replicated in multiple storage providers, and the metadata may include a list of storage providers from which the clients can select (e. g. , randomly) in order to access the file.

US Patent:

20120219968, Aug 30, 2012

Filed:

May 14, 2012

Appl. No.:

13/470665

Inventors:

Helena S. Mancebo - Fremont CA, US
Samuel X. Li - Redmond WA, US
Jianfu L. Wang - Union City CA, US

Assignee:

Multispan, Inc. - Hayward CA

International Classification:

G01N 33/566
G01N 21/64
G01N 33/577

US Classification:

435 721

Abstract:

The present invention provides expression vectors that facilitate high levels of expression of GPCR proteins. Encompassed by the invention are methods and compositions for recombinant cell lines expressing GPCR proteins with the aid of the expression vectors of the instant invention. The recombinant cell lines of the instant invention express GPCR proteins at levels of at least about 150,000 copies of the protein per cell. The present invention also provides methods and compositions for raising antibodies against GPCR proteins using the high expressing recombinant cells of the instant invention.

US Patent:

20130013619, Jan 10, 2013

Filed:

Sep 14, 2012

Appl. No.:

13/620001

Inventors:

Francesco Lacapra - Sunnyvale CA, US
Peter Wallace Steele - Campbell CA, US
Bruno Sartirana - Loomis CA, US
Ernest Ying Sue Hua - Cupertino CA, US
I Chung Joseph Lin - San Jose CA, US
Samuel Sui-Lun Li - Pleasanton CA, US
Nathanael John Diller - San Francisco CA, US
Thomas Reynold Ramsdell - Palos Verdes CA, US
Don Nguyen - Tracy CA, US
Kyle Dinh Tran - San Jose CA, US

Assignee:

OVERLAND STORAGE, INC. - San Diego CA

International Classification:

G06F 17/30

US Classification:

707747, 707E17002, 707E1701

Abstract:

Peer-to-peer redundant file server system and methods include clients that determine a target storage provider to contact for a particular storage transaction based on a pathname provided by the filesystem and a predetermined scheme such as a hash function applied to a portion of the pathname. Servers use the same scheme to determine where to store relevant file information so that the clients can locate the file information. The target storage provider may store the file itself and/or may store metadata that identifies one or more other storage providers where the file is stored. A file may be replicated in multiple storage providers, and the metadata may include a list of storage providers from which the clients can select (e.g., randomly) in order to access the file.

US Patent:

20130013639, Jan 10, 2013

Filed:

Sep 14, 2012

Appl. No.:

13/620026

Inventors:

Francesco Lacapra - Sunnyvale CA, US
Peter Wallace Steele - Campbell CA, US
Bruno Sartirana - Loomis CA, US
Ernest Ying Sue Hua - Cupertino CA, US
I Chung Joseph Lin - San Jose CA, US
Samuel Sui-Lun Li - Pleasanton CA, US
Nathanael John Diller - San Francisco CA, US
Thomas Reynold Ramsdell - Palos Verdes CA, US
Don Nguyen - Tracy CA, US
Kyle Dinh Tran - San Jose CA, US

Assignee:

OVERLAND STORAGE, INC. - San Diego CA

International Classification:

G06F 17/30

US Classification:

707770, 707E17001

Abstract:

Peer-to-peer redundant file server system and methods include clients that determine a target storage provider to contact for a particular storage transaction based on a pathname provided by the filesystem and a predetermined scheme such as a hash function applied to a portion of the pathname. Servers use the same scheme to determine where to store relevant file information so that the clients can locate the file information. The target storage provider may store the file itself and /or may store metadata that identifies one or more other storage providers where the file is stored. A file may be replicated in multiple storage providers, and the metadata may include a list of storage providers from which the clients can select (e.g., randomly) in order to access the file.

US Patent:

20130013654, Jan 10, 2013

Filed:

Sep 14, 2012

Appl. No.:

13/619368

Inventors:

Francesco Lacapra - Sunnyvale CA, US
Peter Wallace Steele - Campbell CA, US
Bruno Sartirana - Loomis CA, US
Ernest Ying Sue Hua - Cupertino CA, US
I Chung Joseph Lin - San Jose CA, US
Samuel Sui-Lun Li - Pleasanton CA, US
Nathanael John Diller - San Francisco CA, US
Thomas Reynold Ramsdell - Palos Verdes CA, US
Don Nguyen - Tracy CA, US
Kyle Dinh Tran - San Jose CA, US

Assignee:

OVERLAND STORAGE, INC. - San Diego CA

International Classification:

G06F 17/30

US Classification:

707822, 707E1701

Abstract:

Peer-to-peer redundant file server system and methods include clients that determine a target storage provider to contact for a particular storage transaction based on a pathname provided by the filesystem and a predetermined scheme such as a hash function applied to a portion of the pathname. Servers use the same scheme to determine where to store relevant file information so that the clients can locate the file information. The target storage provider may store the file itself and/or may store metadata that identifies one or more other storage providers where the file is stored. A file may be replicated in multiple storage providers, and the metadata may include a list of storage providers from which the clients can select (e.g., randomly) in order to access the file.

US Patent:

20130013655, Jan 10, 2013

Filed:

Sep 14, 2012

Appl. No.:

13/619908

Inventors:

Francesco Lacapra - Sunnyvale CA, US
Peter Wallace Steele - Campbell CA, US
Bruno Sartirana - Loomis CA, US
Ernest Ying Sue Hua - Cupertino CA, US
I Chung Joseph Lin - San Jose CA, US
Samuel Sui-Lun Li - Pleasanton CA, US
Nathanael John Diller - San Francisco CA, US
Thomas Reynold Ramsdell - Palos Verdes CA, US
Don Nguyen - Tracy CA, US
Kyle Ding Tran - San Jose CA, US

Assignee:

OVERLAND STORAGE, INC. - San Diego CA

International Classification:

G06F 17/30

US Classification:

707827, 707E1701

Abstract:

Peer-to-peer redundant file server system and methods include clients that determine a target storage provider to contact for a particular storage transaction based on a pathname provided by the filesystem and a predetermined scheme such as a hash function applied to a portion of the pathname. Servers use the same scheme to determine where to store relevant file information so that the clients can locate the file information. The target storage provider may store the file itself and/or may store metadata that identifies one or more other storage providers where the file is stored. A file may be replicated in multiple storage providers, and the metadata may include a list of storage providers from which the clients can select (e.g., randomly) in order to access the file.