Samuel I Rapaport

US Patent:

6867045, Mar 15, 2005

Filed:

Jun 28, 2000

Appl. No.:

09/606779

Inventors:

John H. Griffin - Del Mar CA, US
Samuel I. Rapaport - La Jolla CA, US
Dzung T. Le - San Diego CA, US

Assignee:

The Scripps Research Institute - La Jolla CA
The Regents of the University of California - Oakland CA

International Classification:

G01N033/86

US Classification:

436 69, 435 13, 436 86

Abstract:

The present invention provides an in vitro method useful for the diagnosis of a thrombotic disorder in a subject, having or at risk of having the disorder. Specifically, the disorder exemplified herein is associated with APC resistant Factor V and Va. The clotting time of a test sample is analyzed in the presence and absence of APC and compared with a standard reference sample in order to diagnose the subject.

US Patent:

20050260696, Nov 24, 2005

Filed:

Mar 15, 2005

Appl. No.:

11/081858

Inventors:

John Griffin - Del Mar CA, US
Samuel Rapaport - La Jolla CA, US
Dzung Le - San Diego CA, US

International Classification:

C12Q001/56

US Classification:

435013000

Abstract:

The present invention provides an in vitro method useful for the diagnosis of a thrombotic disorder in a subject, having or at risk of having the disorder. Specifically, the disorder exemplified herein is associated with APC resistant Factor V and Va. The clotting time of a test sample is analyzed in the presence and absence of APC and compared with a standard reference sample in order to diagnose the subject.

US Patent:

57053952, Jan 6, 1998

Filed:

Nov 14, 1994

Appl. No.:

8/339828

Inventors:

John H. Griffin - Del Mar CA
Samuel I. Rapaport - La Jolla CA
Dzung T. Le - San Diego CA

Assignee:

The Scripps Research Institute - La Jolla CA
The Regents of the University of California - Oakland CA

International Classification:

G01N 3386

US Classification:

436 69

Abstract:

The present invention provides an in vitro method useful for the diagnosis of a thrombotic disorder in a subject, having or at risk of having the disorder. Specifically, the disorder exemplified herein is associated with APC resistant Factor V and Va. The clotting time of a test sample is analyzed in the presence and absence of APC and compared with a standard reference sample in order to diagnose the subject.

US Patent:

60837578, Jul 4, 2000

Filed:

Nov 10, 1998

Appl. No.:

9/189343

Inventors:

John H. Griffin - Del Mar CA
Samuel I. Rapaport - La Jolla CA
Dzung T. Le - San Diego CA

Assignee:

The Scripps Research Institute - La Jolla CA

International Classification:

G01N 3386
C12Q 156

US Classification:

436 69

Abstract:

The present invention provides an in vitro method useful for the diagnosis of a thrombotic disorder in a subject, having or at risk of having the disorder. Specifically, the disorder exemplified herein is associated with APC resistant Factor V and Va. The clotting time of a test sample is analyzed in the presence and absence of APC and compared with a standard reference sample in order to diagnose the subject.

US Patent:

58342230, Nov 10, 1998

Filed:

Dec 18, 1997

Appl. No.:

8/993664

Inventors:

John H. Griffin - Del Mar CA
Samuel I. Rapaport - La Jolla CA
Dzung T. Le - San Diego CA

Assignee:

The Scripps Research Institute - La Jolla CA
The Regents of the University of California - Oakland CA

International Classification:

C12Q 156
C12Q 100
G01N 3353
G01N 3300

US Classification:

435 13

Abstract:

The present invention provides an in vitro method useful for the diagnosis of a thrombotic disorder in a subject, having or at risk of having the disorder. Specifically, the disorder exemplified herein is associated with APC resistant Factor V and Va. The clotting time of a test sample is analyzed in the presence and absence of APC and compared with a standard reference sample in order to diagnose the subject.