Sandeep Gupta

US Patent:

6687528, Feb 3, 2004

Filed:

Sep 28, 2001

Appl. No.:

09/967297

Inventors:

Sandeep N. Gupta - Baltimore MD
Garth M. Beache - Baltimore MD
Daniel A. Herzka - Silver Spring MD

Assignee:

GE Medical Systems Global Technology Company LLC - Waukesha WI
John Hopkins University - Baltimore MD

International Classification:

A61B 5055

US Classification:

600410, 382294, 382131, 382278

Abstract:

The present invention is a method and apparatus for semi-automatically registering low signal to noise ratio relaxation-time images, with particular application to tracking motion in moving organs and quantifying myocardial perfusion reserve. For each image acquired in a time series, a corresponding high signal to noise ratio image is extrapolated from the collected data. The high signal to noise ratio images are registered to track motion, and the resulting registration data is copied onto the corresponding relaxation time image.

US Patent:

7280862, Oct 9, 2007

Filed:

Aug 18, 2004

Appl. No.:

10/711025

Inventors:

Sandeep Narendra Gupta - Hanover MD, US
Glenn Scott Slavin - Silver Spring MD, US
Thomas Kwok-Fah Foo - Potomac MD, US

Assignee:

General Electric Company - Schenectady NY

International Classification:

A61B 5/05
A61B 5/02

US Classification:

600410, 600425, 600481, 600407

Abstract:

A system and a method for obtaining a digital image of a heart of a person are provided. The system scans an internal anatomy of a chest region of the person to obtain scanning data. The system further generates a digital image of four chambers of the heart based on the scanning data.

US Patent:

20030039949, Feb 27, 2003

Filed:

Apr 19, 2002

Appl. No.:

10/125890

Inventors:

David Cappellucci - Wayland MA, US
Kirby Mansfield - Pepperell MA, US
Sandeep Gupta - Somerville MA, US

International Classification:

G09B007/00

US Classification:

434/362000

Abstract:

The present invention is directed to a scalable method and system for efficiently correlating large volumes of information resources. In an e-learning system many large and disparate of educational information resources can be combined and accessed quickly and efficiently. The system made very scalable by the use of central database of learning objectives referred to as a set of Master Learning Objectives or MLOs. Each information object and element of each information resource can be correlated to one or more MLOs in order to establish a link or relationship between the information object or element and the MLO. Once an information object or element is linked to an MLO, additional information objects and elements corresponding to the same subject as the first information object or element can be located by searching for all other information objects and elements linked to the same MLO. In addition, the MLOs can be hierarchically arranged in tree structure in order to further facilitate identifying information objects and elements that correspond to a given MLO or subset of MLOs.

US Patent:

20030078934, Apr 24, 2003

Filed:

Apr 19, 2002

Appl. No.:

10/125891

Inventors:

David Cappellucci - Wayland MA, US
Kirby Mansfield - Pepperell MA, US
Sandeep Gupta - Somerville MA, US

International Classification:

G06F007/00

US Classification:

707/101000

Abstract:

The present invention is directed to a scalable method and system for providing large groups of users with access to a large group of disparate information resources. The system is highly scalable and provide for a layered architecture that enables rapid application development, high availability and strong system security. The method and system can also provide the ability to customize the information provided by allowing the user to locate, assemble, format and combine information elements from diverse information resources in real time.

US Patent:

20070082920, Apr 12, 2007

Filed:

Oct 6, 2005

Appl. No.:

11/244614

Inventors:

Yongsheng Song - Guilford CT, US
Yongchun Hou - Mentor OH, US
Sandeep Gupta - Concord OH, US
Aimee Reed - Willoughby OH, US
Debasis Ghosh - Perrysburg OH, US

International Classification:

A61K 31/519
C07D 487/02

US Classification:

514264100, 544250000, 544279000, 514267000

Abstract:

Disclosed herein are pyrido[2,3-d]pyrimidines having the structure

US Patent:

20080150532, Jun 26, 2008

Filed:

Dec 21, 2006

Appl. No.:

11/614593

Inventors:

Glenn Scott Slavin - Silver Spring MD, US
Sandeep Narendra Gupta - Hanover MD, US

Assignee:

GENERAL ELECTRIC COMPANY - Schenectady NY

International Classification:

G01R 33/50
G01R 33/48

US Classification:

324318, 702 19

Abstract:

A method for rapid measurement of T relaxation comprises a gated, multi-time-point saturation-recovery experiment. Each saturation-recovery experiment may include multiple gating intervals to increase dynamic range of the T measurement. Multiple saturation-recovery experiments may also be used to improve accuracy and signal-to-noise of the T measurement.

US Patent:

20100273776, Oct 28, 2010

Filed:

Mar 29, 2007

Appl. No.:

12/294893

Inventors:

Susan L. Lindquist - Chestnut Hill MA, US
Tiago Outeiro - Cambridge MA, US
James Fleming - Somerville MA, US
Christine Ellen Bulawa - Arlington MA, US
Charlotte Weigel - Melrose MA, US
Feng Liang - Sudbury MA, US
Sandeep Gupta - Concord OH, US
Amy Ripka - Winthrop MA, US

Assignee:

FOLDRx PHARMACEUTICALS, INC - Cambridge MA
WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH - Cambridge MA

International Classification:

A61K 31/519
A61K 31/4045
A61K 31/416
A61K 31/454
A61K 31/445
A61K 31/435
A61K 31/55
C07D 487/04
C07D 209/14
C07D 231/56
C07D 471/04
A61P 43/00
A61P 25/16
A61P 25/28
C12N 5/07

US Classification:

514215, 5142621, 514415, 514406, 514303, 514319, 514297, 544262, 548511, 5483611, 546119, 546120, 544280, 435375

Abstract:

Compounds and compositions are provided for treatment or amelioration of one or more symptoms of α-synuclein toxicity, α-synuclein mediated diseases or diseases in which α-synuclein fibrils are a symptom or cause of the disease.

US Patent:

62926837, Sep 18, 2001

Filed:

May 18, 1999

Appl. No.:

9/313910

Inventors:

Sandeep Narendra Gupta - Baltimore MD
Marshall Sussman - Toronto, CA
Graham Wright - Toronto, CA

Assignee:

General Electric Company - Milwaukee WI

International Classification:

A61B 5055

US Classification:

600410

Abstract:

The present invention relates to magnetic resonance imaging (MRI) and includes a method and apparatus to track motion of anatomy or medical instruments, for example, between MR images. The invention includes acquiring a time series of MR images of a region of interest, where the region of interest contains the anatomy or structure that is prone to movement, and the MR images contain signal intensity variations. The invention includes identifying a local reference region in the region of interest of a reference image and acquired from the time series. The local reference region of the reference image is compared to that of the other MR images and a translational displacement is determined between the local reference region of the reference image and of another MR image. The translational displacement has signal intensity invariance and can accurately track anatomy motion or the movement of a medical instrument during an invasive procedure. The translational displacement can be used to align the images for automatic registration, such as in myocardial perfusion imaging, MR angiography, fMRI, or in any other procedure in which motion tracking is advantageous.