Sandra Lee Jacobson

US Patent:

59898976, Nov 23, 1999

Filed:

Mar 24, 1998

Appl. No.:

9/047026

Inventors:

Lorraine Pillus - Boulder CO
Astrid Clarke - Longmont CO
Joanna Lowell - Boulder CO
Sandra Jacobson - Lafayette CO
Cheryl Reifsnyder - Boulder CO

Assignee:

University Technology Corporation - Boulder CO

International Classification:

C12N 119
C12N 118
C12N 1531
C12N 1563

US Classification:

4352542

Abstract:

The present invention provides the yeast genes SAS2, SAS3 and ESA1 and the proteins encoded thereby. SAS2, SAS3 and ESA1 genes of members of the genus Saccharomyces are provided, particularly the SAS2, SAS3 and ESA1 genes of S. cerevisiae. Also provided are yeast SAS2, SAS3 and ESA1 coding sequences. Specifically provided are the SAS2, SAS3 and ESA1 coding sequences of members of the genus Saccharomyces, and more specifically of S. cerevisiae. Genes of this invention comprise protein coding sequences as well as the regulatory regions that control expression of the encoded protein. Of most interest are SAS2, SAS3, and ESA1 genes of yeast including those of the genus Saccharomyces which are 90% or more homologous to the corresponding genes of S. cerevisiae. Specifically provided are DNA constructs comprising purified and isolated DNA molecules comprising SAS2, SAS3 or ESA1 coding sequences that encode proteins from a strain of S.