Sarah Jean Hurst

US Patent:

20080311669, Dec 18, 2008

Filed:

Jun 4, 2008

Appl. No.:

12/133243

Inventors:

Chad A. Mirkin - Wilmette IL, US
Sarah J. Hurst - Evanston IL, US
Min Su Han - Kyung Ju, KR
Abigail K.R. Lytton-Jean - Cambridg MA, US

Assignee:

NORTHWESTERN UNIVERSITY - Evanston IL

International Classification:

G01N 33/50

US Classification:

436 94, 977924

Abstract:

Disclosed herein are methods of screening sequence selectivity of oligonucleotide-binding molecules using a gold nanoparticle based calorimetric assay.

US Patent:

20100099858, Apr 22, 2010

Filed:

Sep 25, 2007

Appl. No.:

12/441952

Inventors:

Chad A. Mirkin - Wilmette IL, US
Abigail K.R. Lytton-Jean - Chicago IL, US
Sarah J. Hurst - Evanston IL, US

International Classification:

C07H 21/04

US Classification:

536 231, 977773

Abstract:

Increasing the amount of DNA loaded onto gold nanoparticles is disclosed. More particularly, methods of maximizing DNA loading, using salting techniques, sonication, temperature and other such procedures are disclosed.

US Patent:

20100234579, Sep 16, 2010

Filed:

May 12, 2008

Appl. No.:

12/599474

Inventors:

Chad A. Mirkin - Wilmette IL, US
Jae-Seung Lee - Seongbuk-gu, KR
Abigail K.R. Lytton-Jean - Cambridge MA, US
Sarah J. Hurst - Chicago IL, US

Assignee:

NORTH WESTERN UNIVERSITY - Evanston

International Classification:

C07K 16/00
C07H 21/00
C07K 14/00

US Classification:

5303911, 536 231, 530400, 977773

Abstract:

The present invention concerns the use of binding agent-functionalized silver nanoparticles for a variety of uses, including molecular diagnostic labels, synthons in programmable materials synthesis approaches, and functional components for nanoelectronic devices. More specifically, the invention provides a new strategy for preparing silver nanoparticle-binding agent conjugates that are based upon moieties with triple cyclic disulfide-anchoring groups.

US Patent:

20100291697, Nov 18, 2010

Filed:

Jul 23, 2008

Appl. No.:

12/670194

Inventors:

Chad A. Mirkin - Wilmette IL, US
Can Xue - Evanston IL, US
Xiaodong Chen - Evanston IL, US
Sarah J. Hurst - Evanston IL, US

International Classification:

G01N 33/00

US Classification:

436 94

Abstract:

Coated colloidal materials, methods for making coated colloidal materials, and methods of using coated colloidal materials are disclosed. The method yields coated colloidal materials where the optical characteristics of the core is not adversely affected. The coated colloidal materials can be self-assembled into films, layers, or structures and used in the detection of analytes through detection assays.

US Patent:

20120164396, Jun 28, 2012

Filed:

Jun 17, 2008

Appl. No.:

12/140780

Inventors:

Chad A. Mirkin - Wilmette IL, US
Ling Huang - Painted Port NY, US
Fengwei Huo - Evanston IL, US
Sarah J. Hurst - Evanston IL, US
Lidong Qin - Pasadena CA, US
Jae-Won Jang - Evanston IL, US
Joseph J. Kakkassery - Evanston IL, US

International Classification:

B05D 5/00
B32B 3/10
B82Y 40/00

US Classification:

4281951, 427256, 427265, 977887

Abstract:

Provided is a direct write patterning method utilizing a mixture comprising an ink of choice and an ink carrier matrix. The method involves disposing the mixture on a tip or stamp and transporting the mixture from the tip or stamp on a surface to form a pattern that contains the ink. The method does not require chemical or physical modification of either the tip or stamp or the surface prior to transporting the mixture to the surface. The method can be applied for patterning hard inks such as nanomaterials and crystallized polymers and soft inks such as biomaterials including peptides and proteins. Also provided are related biomaterial and hard ink arrays.