Scott Conrad Allen

US Patent:

20020081665, Jun 27, 2002

Filed:

Jan 31, 2001

Appl. No.:

09/775938

Inventors:

Margo Haygood - La Jolla CA, US
Seana Davidson - La Jolla CA, US
Scott Allen - San Diego CA, US
Mark Hildebrand - La Jolla CA, US

International Classification:

C12Q001/68
C07H017/08
C07H021/04
C12P019/62
C12N001/21

US Classification:

435/076000, 536/007100, 536/023200, 435/252300, 435/006000, 514/027000, 514/028000

Abstract:

The present invention recognizes that marine organisms comprise nucleic acid molecules that encode polypeptides that catalyze the synthesis of bioactive compounds, such as polyketides including bryopyran rings, such as bryostatins. One aspect of the present invention is a composition including at least one nucleic acid molecule that encodes at least one polypeptide that catalyzes at least one step in the synthesis of at least one polyketide such as a bryopyran ring, wherein said at least one nucleic acid molecule is derived from at least one marine organism. A second aspect of the present invention is a composition including a library of nucleic acid molecules of the present invention. These nucleic acid molecules can be used in a combinatorial biosynthesis of polyketides, bryopyran rings and bryostatins.

US Patent:

55674895, Oct 22, 1996

Filed:

Mar 23, 1994

Appl. No.:

8/216905

Inventors:

Scott I. Allen - Newark OH
Michael Ferguson - Granville OH
Harvey Tung - Newark OH

Assignee:

The Dow Chemical Company - Midland MI

International Classification:

B32B 2708

US Classification:

428 341

Abstract:

An oxygen and moisture impermeable multilayer barrier film which is free of halogens and which may be produced by coextrusion or lamination techniques is provided. The film provides excellent adhesion between layers, has quietness, odor barrier, and softness characteristics, and provides a heat sealable surface for the fabrication of bags. The barrier film includes a halogen-free barrier layer and at least one heat sealable skin layer. The heat sealable skin layer includes either a thermoplastic polyurethane, a substantially linear copolymer of ethylene and an. alpha. -olefin having a density in the range of from about 0. 87-0. 92 gm/cc and from about 0. 01 to 3 long chain branches/1000 carbon atoms along the polymer backbone, a homogeneously-branched linear polyolefin resin, or a blend of an ultra low density polyolefin resin with a copolymer of ethylene and vinyl acetate.

US Patent:

54685265, Nov 21, 1995

Filed:

Sep 20, 1993

Appl. No.:

8/123270

Inventors:

Scott I. Allen - Newark OH
Duane F. Foye - Beaverton MI
Michael Ferguson - Granville OH

Assignee:

The Dow Chemical Company - Midland MI

International Classification:

B32B 2736
B32B 708

US Classification:

428 354

Abstract:

An oxygen and moisture impermeable multilayer barrier film is provided including a barrier layer comprising a homopolymer of vinylidene chloride or a copolymer of vinylidene chloride and vinyl chloride or methyl methacrylate. The barrier layer may be coated onto or coextruded with a water soluble film layer comprising a blend of a water soluble polymer such as polyvinyl alcohol, polycaprolactone, or polyethyloxozaline and a thermoplastic polyurethane. The multilayer film may be used for reusable or disposable ostomy bags and for heat sealable bags used in packaging agricultural chemicals, detergents, and other household chemicals.

US Patent:

55674887, Oct 22, 1996

Filed:

Mar 23, 1994

Appl. No.:

8/216903

Inventors:

Scott I. Allen - Newark OH
Michael Ferguson - Granville OH
Harvey Tung - Newark OH

Assignee:

The Dow Chemical Company - Midland MI

International Classification:

B32B 2732

US Classification:

428 341

Abstract:

An oxygen and moisture impermeable multilayer barrier film is provided including a barrier layer comprising a homopolymer of vinylidene chloride or a copolymer of vinylidene chloride and vinyl chloride or methyl methacrylate. The barrier layer is coextruded with or laminated to at least one heat sealable skin layer comprising a thermoplastic polyurethane, a substantially linear copolymer of ethylene and an. alpha. -olefin, or a homogeneously-branched linear olefin resin to form the barrier film. The multilayer film may be used for reusable ostomy bags, for systems for the transdermal delivery of drugs, and for heat sealable bags used in packaging.