Sean Chen

US Patent:

8153677, Apr 10, 2012

Filed:

Jan 24, 2011

Appl. No.:

13/012351

Inventors:

Denis E. Ryono - Minneapolis MN, US
Peter T. W. Cheng - Princeton NJ, US
Scott A. Bolton - Newtown PA, US
Sean Chen - Princeton NJ, US
Yan Shi - Flourtown PA, US
Wei Meng - Pennington NJ, US
Joseph A. Tino - Lawrenceville NJ, US
Richard B. Sulsky - West Trenton NJ, US

Assignee:

Bristol-Myers Squibb Company - Princeton NJ

International Classification:

A61K 31/415

US Classification:

514407, 5483751

Abstract:

Compounds are provided which are phosphonate and phosphinate activators and thus are useful in treating diabetes and related diseases and have the structure.

US Patent:

8614332, Dec 24, 2013

Filed:

Feb 15, 2012

Appl. No.:

13/397123

Inventors:

Denis E. Ryono - Minneapolis MN, US
Peter T. W. Cheng - Princeton NJ, US
Scott A. Bolton - Newtown PA, US
Sean Chen - Princeton NJ, US
Yan Shi - Flourtown PA, US
Wei Meng - Pennington NJ, US
Joseph A. Tino - Lawrenceville NJ, US
Richard B. Sulsky - West Trenton NJ, US

Assignee:

Bristol-Myers Squibb Company - Princeton NJ

International Classification:

C07D 231/00

US Classification:

5483751, 544408, 548953

Abstract:

Compounds are provided which are phosphonate and phosphinate activators and thus are useful in treating diabetes and related diseases and have the structureA method for treating diabetes and related diseases employing the above compounds is also provided.

US Patent:

20220211478, Jul 7, 2022

Filed:

Jan 6, 2021

Appl. No.:

17/142712

Inventors:

- Minneapolis MN, US
Sean Chen - Plymouth MN, US
Anne R. Kamm - White Bear Lake MN, US
Paul C. Ray - Maple Grove MN, US

Assignee:

MEDTRONIC INC. - Minneapolis MN

International Classification:

A61F 2/00
A61N 1/375
A61L 31/10

Abstract:

A package for a surgical implant includes a body having a side wall including opposite top and bottom ends. The body includes a bottom wall coupled to the bottom end. The body includes a flange extending outwardly from the top end. Inner surfaces of the walls define a cavity. The top end defines an opening that is in communication with the cavity. An insert extends from the bottom wall such that the insert is positioned in the cavity. A lid is configured to be coupled to the flange such that the lid covers the opening. Devices, kits and systems are disclosed.

US Patent:

20220211922, Jul 7, 2022

Filed:

Jan 6, 2021

Appl. No.:

17/142694

Inventors:

- Minneapolis MN, US
Sean Chen - Plymouth MN, US
Anne R. Kamm - White Bear Lake MN, US
Paul C. Ray - Maple Grove MN, US

Assignee:

MEDTRONIC INC. - Minneapolis MN

International Classification:

A61L 31/16
A61L 31/04
A61L 31/10
A61K 9/00
A61K 47/42
A61K 45/06
A61K 31/496
A61K 31/65
A61K 31/137
A61K 31/195
A61K 31/722
A61K 31/717

Abstract:

A surgical device configured to surround an implantable medical device that includes a collagen membrane and a coating embedded in the membrane The coating including at least one active pharmaceutical ingredient.

US Patent:

20230077402, Mar 16, 2023

Filed:

Sep 13, 2021

Appl. No.:

17/473123

Inventors:

- Minneapolis MN, US
Sean Chen - Plymouth MN, US
Kasyap V. Seethamraju - Eden Prairie MN, US
Charlene X. Yuan - North Plymouth MN, US
Raman V. Bahulekar - Kendall Park NJ, US
Joseph L. Kalscheuer - Minneapolis MN, US

Assignee:

MEDTRONIC INC. - Minneapolis MN

International Classification:

A61L 31/10
A61L 31/14
A61L 31/16
A61K 31/196
A61K 31/496
A61K 31/65

Abstract:

A surgical device includes a substrate and a first coating that covers at least a portion of the substrate. The first coating includes a first polymer. The first coating having antibiotics dispersed in the first polymer such that the first polymer releases the antibiotics as the first polymer degrades. A second coating covers at least a portion of the first coating. The second coating includes a second polymer. The second polymer includes an alginate. The second coating has a hemostatic agent dispersed in the second polymer such that the second polymer releases the hemostatic agent as the second polymer degrades. The hemostatic agent is selected from epinephrine, tranexamic acid, chitosan and oxidized regenerated cellulose. In some embodiments, systems and methods are disclosed.

US Patent:

20230079760, Mar 16, 2023

Filed:

Sep 13, 2021

Appl. No.:

17/473119

Inventors:

- Minneapolis MN, US
Sean Chen - Plymouth MN, US
Kasyap V. Seethamraju - Eden Prairie MN, US
Charlene X. Yuan - North Plymouth MN, US
Raman V. Bahulekar - Kendall Park NJ, US

Assignee:

MEDTRONIC INC. - Minneapolis MN

International Classification:

A61L 31/16
A61L 31/04

Abstract:

A surgical device includes a substrate and a first coating that covers at least a portion of the substrate. The first coating includes a first polymer. The first coating having antibiotics dispersed in the first polymer such that the first polymer releases the antibiotics as the first polymer degrades. A second coating covers at least a portion of the first coating. The second coating includes a second polymer. The second coating has ellagic acid dispersed in the second polymer such that the second polymer releases the ellagic acid as the second polymer degrades. In some embodiments, systems and methods are disclosed.