- North Chicago IL, US Vincent S. Chan - Evanston IL, US Kassibla E. Dempah - Chicago IL, US Brian P. Enright - Gurnee IL, US Rodger F. Henry - Wildwood IL, US Raimundo Ho - Chicago IL, US Ye Huang - Gurnee IL, US Alexander D. Huters - Chicago IL, US Russell C. Klix - Buffalo Grove IL, US Scott W. Krabbe - Lindenhurst IL, US Philip R. Kym - Libertyville IL, US Yanbin Lao - Lake Bluff IL, US Xiaochun Lou - Long Grove IL, US Sean E. Mackey - Grayslake IL, US Mark A. Matulenko - Libertyville IL, US Peter T. Mayer - Libertyville IL, US Christopher P. Miller - Lake Forest IL, US James Stambuli - Worcester MA, US Valentino J. Stella - Lawrence KS, US Eric A. Voight - Pleasant Prairie WI, US Zhi Wang - Libertyville IL, US Geoff G. Zhang - Vernon Hills IL, US
The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
Levodopa And Carbidopa Intestinal Gel And Methods Of Use
- North Chicago IL, US Alexandru DEAC - Skokie IL, US Ye HUANG - Gurnee IL, US Sean E. MACKEY - Grayslake IL, US Randy A. MENGES - Lake Villa IL, US Jayne ZIMMERMAN - Deerfield IL, US
The present disclosure relates to (a) an improved pharmaceutical composition comprising a levodopa active agent and a carbidopa active agent (b) methods of producing the pharmaceutical composition and (c) methods of treating Parkinson's disease and associated conditions comprising administering the pharmaceutical composition to a subject with Parkinson's disease.
- North Chicago IL, US Vincent S. Chan - Evanston IL, US Kassibla E. Dempah - Chicago IL, US Brian P. Enright - Gumee IL, US Rodger F. Henry - Wildwood IL, US Raimundo Ho - Chicago IL, US Ye Huang - Gumee IL, US Alexander D. Huters - Chicago IL, US Russell C. Klix - Buffalo Grove IL, US Scott W. Krabbe - Lindenhurst IL, US Philip R. Kym - Libertyville IL, US Yanbin Lao - Lake Bluff IL, US Xiaochun Lou - Long Grove IL, US Sean E. Mackey - Grayslake IL, US Mark A. Matulenko - Libertyville IL, US Peter T. Mayer - Libertyville IL, US Christopher P. Miller - Lake Forest IL, US James Stambuli - Buffalo Grove IL, US Valentino J. Stella - Lawrence KS, US Eric A. Voight - Pleasant Prairie WI, US Zhi Wang - Libertyville IL, US Geoff Zhang - Vernon Hills IL, US
The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
- North Chicago IL, US Vincent S. Chan - Evanston IL, US Kassibla E. Dempah - Chicago IL, US Brian P. Enright - Gurnee IL, US Rodger F. Henry - Wildwood IL, US Raimundo Ho - Chicago IL, US Ye Huang - Gurnee IL, US Alexander D. Huters - Chicago IL, US Russell C. Klix - Buffalo Grove IL, US Scott W. Krabbe - Lindenhurst IL, US Philip R. Kym - Libertyville IL, US Yanbin Lao - Lake Bluff IL, US Xiaochun Lou - Long Grove IL, US Sean E. Mackey - Grayslake IL, US Mark A. Matulenko - Libertyville IL, US Peter T. Mayer - Libertyville IL, US Christiopher P. Miller - Lake Forest IL, US James Stambuli - Buffalo Grove IL, US Valentino J. Stella - Lawrence KS, US Eric A. Voight - Pleasant Prairie WI, US Zhi Wang - Libertyville IL, US Geoff G. Zhang - Vernon Hills IL, US
The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
Levodopoa And Carbidopa Intestinal Gel And Methods Of Use
- North Chicago IL, US Alexandru DEAC - Skokie IL, US Ye HUANG - Gurnee IL, US Sean E. MACKEY - Grayslake IL, US Randy A. MENGES - Lake Villa IL, US Jayne Zimmerman - Deerfield IL, US
The present disclosure relates to (a) an improved pharmaceutical composition comprising a levodopa active agent and a carbidopa active agent (b) methods of producing the pharmaceutical composition and (c) methods of treating Parkinson's disease and associated conditions comprising administering the pharmaceutical composition to a subject with Parkinson's disease.
Pump, Motor And Assembly For Beneficial Agent Delivery
- NORTH CHICAGO IL, US Rajkumar Conjeevaram - Lake Bluff IL, US Ji Zhou - Lake Villa IL, US Sean Mackey - Grayslake IL, US Kevin Novak - Park Ridge IL, US Ted Hanagan - Libertyville IL, US Mark Panzer - Appleton WI, US Benjamin Greuel - Neenah WI, US Jim Hoch - Appleton WI, US Ryan Thompson - Neenah WI, US
Assignee:
ABBVIE INC. - NORTH CHICAGO IL
International Classification:
A61M 5/168 F04B 43/12 F04B 43/08 A61M 5/142
Abstract:
Device for delivering a beneficial agent to a user includes a cassette including a cassette housing with a fluid reservoir, the cassette housing having a cassette base region, and a delivery tube. The device also includes a pump having a pump housing containing a pump assembly and having a receiving region to receive the cassette base region. The pump assembly includes a fluid drive component, a display, a plurality of input buttons. The pump assembly also includes a first processor coupled to the fluid drive component and the display and configured to reduce power to the fluid drive component and the display when the pump is in an inactive state, and a second processor coupled to the first processor and the plurality of input buttons, the second processor configured to provide an activation signal to the first processor when one or more of the plurality of input buttons is deployed.
- North Chicago IL, US Vincent S. Chan - Evanston IL, US Kassibla Dempah - Chicago IL, US Brian P. Enright - Gurnee IL, US Rodger F. Henry - Wildwood IL, US Raimundo Ho - Chicago IL, US Ye Huang - Gurnee IL, US Alexander D. Huters - Chicago IL, US Russell C. Klix - Buffalo Grove IL, US Scott W. Krabbe - Lindenhurst IL, US Philip R. Kym - Libertyville IL, US Yanbin Lao - Lake Bluff IL, US Xiaochun Lou - Long Grove IL, US Sean E. Mackey - Grayslake IL, US Mark A. Matulenko - Libertyville IL, US Peter T. Mayer - Libertyville IL, US Christopher P. Miller - Lake Forest IL, US James Stambuli - Buffalo Grove IL, US Eric A. Voight - Pleasant Prairie WI, US Zhi Wang - Libertyville IL, US Geoff G. Zhang - Vernon Hills IL, US Valentino J. Stella - Lawrence KS, US
The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
- North Chicago IL, US Vincent S. CHAN - Evanston IL, US Kassibla DEMPAH - Chicago IL, US Brian P. ENRIGHT - Gurnee IL, US Rodger F. HENRY - Wildwood IL, US Raimundo HO - Chicago IL, US Ye HUANG - Gurnee IL, US Alexander D. HUTERS - Chicago IL, US Russell C. KLIX - Buffalo Grove IL, US Scott W. KRABBE - Lindenhurst IL, US Philip R. KYM - Libertyville IL, US Yanbin LAO - Lake Bluff IL, US Xiaochun LOU - Long Grove IL, US Sean E. MACKEY - Grayslake IL, US Mark A. MATULENKO - Libertyville IL, US Peter T. MAYER - Libertyville IL, US Christopher P. MILLER - Lake Forest IL, US James STAMBULI - Buffalo Grove IL, US Eric A. VOIGHT - Pleasant Prairie WI, US Zhi WANG - Libertyville IL, US Geoff G. ZHANG - Vernon Hills IL, US Valentino J. STELLA - Lawrence KS, US
The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
Stanford Hospital Anesthesia 300 Pasteur Dr RM H3580, Stanford, CA 94305 6507236412 (phone), 6507258544 (fax)
Stanford Health Pain Management Clinic 450 Broadway St Pav A, Redwood City, CA 94063 6507236238 (phone), 6507213414 (fax)
Education:
Medical School University of Arizona College of Medicine at Tucson Graduated: 1994
Languages:
English Spanish
Description:
Dr. Mackey graduated from the University of Arizona College of Medicine at Tucson in 1994. He works in Stanford, CA and 1 other location and specializes in Anesthesiology. Dr. Mackey is affiliated with Stanford Hospital and VA Palo Alto Health Care System.
Flickr
Youtube
Dr. Sean Mackey: Are we really helping our pa...
Sean Mackey, M.D., Ph.D, is Chief of the Division of Pain Medicine and...
Duration:
1m 33s
Stanford's Sean Mackey, MD, PhD on "Pain and ...
Sean Mackey, MD, PhD, speaks on "Pain and the Brain" at Stanford Back ...
Duration:
19m 53s
Stanford's Sean Mackey, MD, PhD on "What is C...
Chronic pain is a debilitating disease which affects over 100 million ...
Duration:
2m 32s
An Update on Fibromyalgia
Dr. Sean Mackey, assistant professor of anesthesia at the Stanford Uni...
Duration:
1h 15m 11s
Stanford's Sean Mackey, MD, PhD, on Back Pain...
Talk: Back Pain and the Brain Stanford Back Pain Education Day 2015 Sp...
Duration:
39m 10s
Part One - The Truth About Sean Mackey, the N...
I have been called a liar, defamed and slandered all for telling the t...
Dr. Sean Mackey, a Stanford professor and physician-scientist who co-led the team, said it found that patients often were steered toward costly treatments and pathways of futility rather than be taught to manage pain through strategies and therapies with good evidence.
Date: Apr 05, 2024
Category: Health
Source: Google
The horrors of TMJ: Chronic pain, metal jaws, and futile treatments
Sean Mackey, a Stanford professor who co-led the team, said it found that patients were often steered toward costly treatments and "pathways of futility" instead of being taught to manage their pain through strategies and therapies with "good evidence."
Date: Apr 04, 2024
Category: Health
Source: Google
Medical marijuana may help combat the opioid crisis. But there are better solutions.
One potential wrinkle: We already have a lot of nonopioid pain treatments. As Stanford University pain specialist Sean Mackey previously told me, there are 200-plus nonopioid pain medications, not to mention nonpharmacological approaches. So marijuana isnt providing something entirely new here if i
Date: Apr 30, 2018
Category: Health
Source: Google
America's huge problem with opioid prescribing, in one quote
patients. When prescribed carefully on a schedule that works to diminish the excessive buildup of tolerance, they can work for some people. But Stanford pain specialist Sean Mackey cautions that opioids should not be a first-line treatment due to the grave risks, and alternatives should be tried first.
Date: Sep 18, 2017
Category: Health
Source: Google
How to stop the deadliest drug overdose crisis in American history
As Stanford pain specialist Sean Mackey previously told me, there are non-opioid options for dealing with pain, including non-opioid medications, special physical exercises, alternative medicine approaches (such as acupuncture and meditation), and learning how to self-manage and mitigate pain. (Ther
Date: Aug 01, 2017
Category: Health
Source: Google
Surgeries found to increase risk of chronic opioid use
For a lot of surgeries there is a higher chance of getting hooked on painkillers, said the studys lead author,Eric Sun, MD, PhD, an instructor in anesthesiology at Stanford. Sean Mackey, MD/PhD, professor of anesthesiology, is the senior author of the study.
underlying brain structures and patterns of activity involved in pain. But Sean Mackey, a pain researcher and anesthesiologist at Stanford School of Medicine, says that "what we have never done to date is show that you can use that pattern of information to determine whether someone is in pain or not.
"The question we were trying to answer was can we use neuroimaging to objectively detect whether a person is in a state of pain or not. The answer was yes," Dr. Sean Mackey of the Stanford University School of Medicine in California, whose study appears in the journal PLoS One.