Methods Of Administering -(5--Butyl-Isoxazol-3-Yl)-′-{4-[7-(2-Morpholin-4-Yl-Ethoxy)Imidazo[2,1-B][1,3]Benzothiazol-2-Yl]Phenyl}Urea To Treat Proliferative Disease
Joyce K. James - San Diego CA, US Traci L. Savall - San Diego CA, US Shawn R. Eichelberger - San Diego CA, US
Assignee:
Ambit Biosciences Corporation - San Diego CA
International Classification:
A61K 31/535 A61K 31/41 A61K 31/42
US Classification:
5142315, 514360, 514380
Abstract:
Provided herein are methods of administering N-(5-tert-butyl-isoxazol-3-yl)-N′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea, or a pharmaceutically acceptable salt or solvate thereof, to human patients. Specifically, dosing, dosing schedules or dosing regimens are provided herein. Further, pharmaceutical formulations are provided. Methods of treating proliferative diseases or FLT-3 mediated diseases in humans are also provided.