Shawn Michael O'Malley from Pelham, NH, age 61

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Work:

Liberty Attorney Service

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Monomers For Making Polymeric Cell Culture Surface
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US Patent:

8362144, Jan 29, 2013
Filed:

May 19, 2010
Appl. No.:

12/783156
Inventors:

Arthur W. Martin - Horseheads NY, US
Shawn M. O'Malley - Horseheads NY, US
Simon K. Shannon - Horseheads NY, US
Assignee:

Corning Incorporated - Corning NY
International Classification:

C08F 222/40
C08F 22/40
C08F 20/00
C07D 207/46
US Classification:

525 541, 526262, 5263031, 548542
Abstract:

N-hydroxysuccinimide acrylate ester monomers are described which provide N-hydroxysuccinimide derivatized monomers for the formation of polymeric cell culture surfaces suitable for culture of difficult to culture cells including undifferentiated embryonic stem cells. Methods of making the monomers and are also described.

Dimensional Silica-Based Porous Silicon Structures And Methods Of Fabrication
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US Patent:

8415555, Apr 9, 2013
Filed:

May 4, 2011
Appl. No.:

13/100593
Inventors:

Robert A. Bellman - Painted Post NY, US
Nicholas F. Borrelli - Elmira NY, US
David A. Deneka - Corning NY, US
Shawn M. O'Malley - Horseheads NY, US
Vitor M. Schneider - Painted Post NY, US
Assignee:

Corning Incorporated - Corning NY
International Classification:

H01L 31/042
US Classification:

136255, 136261, 257431, 257466, 257E33005, 257E2109
Abstract:

Methods of fabricating dimensional silica-based substrates or structures comprising a porous silicon layers are contemplated. According to one embodiment, oxygen is extracted from the atomic elemental composition of a silica glass substrate by reacting a metallic gas with the substrate in a heated inert atmosphere to form a metal-oxygen complex along a surface of the substrate. The metal-oxygen complex is removed from the surface of the silica glass substrate to yield a crystalline porous silicon surface portion and one or more additional layers are formed over the crystalline porous silicon surface portion of the silica glass substrate to yield a dimensional silica-based substrate or structure comprising the porous silicon layer. Embodiments are also contemplated where the substrate is glass-based, but is not necessarily a silica-based glass substrate. Additional embodiments are disclosed and claimed.

Derivatized Peptide-Conjugated (Meth) Acrylate Cell Culture Surface And Methods Of Making
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US Patent:

8603820, Dec 10, 2013
Filed:

May 19, 2010
Appl. No.:

12/783125
Inventors:

Arthur W. Martin - Horseheads NY, US
Shawn M. O'Malley - Horseheads NY, US
Simon K. Shannon - Horseheads NY, US
Christopher B. Shogbon - Corning NY, US
Carl M. Truesdale - Corning NY, US
Yue Zhou - Horseheads NY, US
Assignee:

Corning Incorporated - Corning NY
International Classification:

C12N 5/07
US Classification:

435402
Abstract:

A synthetic cell culture surface, prepared from a mixture of at least three (meth)acrylate monomers where one of the monomers has an N-hydroxysuccinimide moiety is provided, which supports the growth of cells including undifferentiated human embryonic stem cells in defined media. Methods for preparing the cell culture surface is also provided.

Methods And Products Related To Drug Screening Using Gene Expression Patterns
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US Patent:

20040009495, Jan 15, 2004
Filed:

Dec 6, 2002
Appl. No.:

10/313335
Inventors:

Shawn O'Malley - Horseheads NY, US
Ken Ross - Boston MA, US
Kim Stegmaier - Brookline MA, US
Todd Golub - Newton MA, US
Brent Stockwell - Boston MA, US
International Classification:

C12Q001/68
G06F019/00
G01N033/48
G01N033/50
C12P019/34
US Classification:

435/006000, 435/091200, 702/020000
Abstract:

The invention involves high throughput methods for identifying properties of cells under a variety of cellular conditions. The high throughput methods have a variety of uses, including methods for identifying cellular modulators such as pharmacological agents or environmental conditions, methods for identifying a cellular phenotype and methods for identifying novel genes.

Methods And Reagents For Improving Nucleic Acid Detection
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US Patent:

20040023248, Feb 5, 2004
Filed:

Dec 9, 2002
Appl. No.:

10/314901
Inventors:

Shawn O'Malley - Millville MA, US
Assignee:

Whitehead Institiute for Biomedical Research - Cambridge MA
International Classification:

C12Q001/68
C08G063/48
C08G063/91
US Classification:

435/006000, 525/054200
Abstract:

The present invention features methods for enhancing nucleic acid molecule detection through the use of dendrimers. Novel dendrimers and methods of making such dendrimers are also features of the present invention.

Methods For Detecting Conformational Changes In Bioentities
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US Patent:

20070148670, Jun 28, 2007
Filed:

Oct 25, 2006
Appl. No.:

11/586363
Inventors:

Shawn M. O'Malley - Horseheads NY, US
International Classification:

C12Q 1/68
G01N 33/53
US Classification:

435 6, 435 71, 977902, 977924
Abstract:

Described herein are methods for detecting conformational changes in bioentities.

Light-Polarizing Article And Process For Making Same
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US Patent:

20090059367, Mar 5, 2009
Filed:

Aug 30, 2007
Appl. No.:

11/897899
Inventors:

Shawn Michael O'Malley - Horseheads NY, US
International Classification:

G02B 5/30
US Classification:

359492, 359483
Abstract:

A process wherein a polymer, such as DNA, having a defined chemical composition and size is used to template the alignment of polarizing species, such as optically active organic dyes or metal nanoparticles having defined compositional characteristics and/or size and shape characteristics, on a surface to manufacture a thin film polarizer; a process where metal nanorods are aligned on a substrate surface or inside a substrate to make a polarizer; and a polarizer thus made. Multi-layered polarizing structure can be created by using the process of the present invention.

Electrically Isolating Polymer Composition
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US Patent:

20100215968, Aug 26, 2010
Filed:

Feb 26, 2009
Appl. No.:

12/393296
Inventors:

Lenwood L. Fields - Painted Post NY, US
Arthur W. Martin - Horseheads NY, US
Shawn M. O'Malley - Horseheads NY, US
Dean M. Thelen - Addison NY, US
International Classification:

B32B 9/04
B32B 15/08
H01B 1/12
H01B 1/02
US Classification:

428447, 428458, 4284111, 252500, 25251921
Abstract:

A composition that includes at least one crosslinkable monomer; at least one hydrophobic monomer; and at least one dielectric constant enhancing agent selected from dielectric enhancing monomers, ferroelectric particulates, and electroactive polymers. Coatings including the polymer of compositions, and articles including electrically isolating layers are also disclosed.