- Boston MA, US Siu Ling WONG - Brookline MA, US Kimberly Lindsay MARTINOD - Kortrijk,, BE Luise ERPENBECK - Göttingen, DE Jörn Thilo WITSCH - FREIBURG, DE Alexander SAVCHENKO - Boston MA, US
Assignee:
THE CHILDREN'S MEDICAL CENTER CORPORATION - Boston MA
International Classification:
A61K 38/46 A61K 45/06
Abstract:
Embodiments of the technology described herein are based, in part, upon the discovery that NETosis, the formation of neutrophil extracellular traps (NETs) is increased in wounds, in organ fibrosis and in subjects with diabetes. Accordingly, methods for treating wounds, fibrosis and NET associated complications in diabetes are provided. The methods comprise administrating a therapeutically effective amount of at least one anti-NET compound to a subject in need of treatment, e.g. a PAD 4 inhibitor, a DNase, a histone-degrading enzyme; an inhibitor of chromatin decondensation; an antibody against a component of a NET; an inhibitor of NET release, a protease inhibitor, or an elastase inhibitor.
Name / Title
Company / Classification
Phones & Addresses
Siu Chuk Wong President
SIU'S PARTY INC
800 Lynnway, Lynn, MA 01905 86 Adam St #2, Malden, MA 02148
Siu Ming Wong Manager
C&W International Enterprises (USA) LLC
Siu C. Wong Secretary
E-Z Party Store Inc Ret Alcoholic Beverages · Ret Misc Merchandise
86 Adams St, Malden, MA 02148
Siu Ming Wong President
3POEMS CORPORATION
115 Kingston St, Boston, MA 02111
Siu Ngan Wong Vice president
TOBIKO JAPANESE FUSION, INCORPORATED
103 Nagog Park, Acton, MA 01720 8 Connolly St, Randolph, MA 02368
Siu Wong Vantive Database Administrator
Seachange Systems Information Technology and Services · Telecommunications · Mfg Digital Video Systems/Television Equipment · Video Distribution & Software Development · Mfg Computer Systems for Cable Industry · Mfg Radio/TV Communication Equipment Commercial Physical Research
PO Box 391, Greenville, NH 03048 50 Nagog Park, Acton, MA 01720 Acton, MA 01720 47 Main St, Mason, NH 03048 9788970100, 6038785055, 9782638071
Real Estate Residential Homes Investment Properties New Home Sales First Time Home Buyers Short Sales Condos Sales Sellers Real Estate Transactions Investments Relocation Single Family Homes Buyer Representation Foreclosures New Homes Referrals Listings Reo Investors Townhomes Luxury
Dr. Wong graduated from the Univ De L'etat A Liege, Fac De Med, Liege, Belgium in 1987. He works in South El Monte, CA and specializes in Cardiovascular Disease and Internal Medicine.
El Vista Elementary School Modesto CA 1985-1987, Rose Avenue Elementary School Modesto CA 1987-1988, Rolling Hills Middle School Watsonville CA 1988-1991
Reference: Conferring liver selectivity to a thyromimetic using a novel nanoparticle increases therapeutic efficacy in a diet-induced obesity animal model by Ruiling Wu, Theeraphop Prachyathipsakul, Jiaming Zhuang, Hongxu Liu, Yanhui Han, Bin Liu, Shuai Gong, Jingyi Qiu, Siu Wong, Alexander Ribbe,