Stanley P Carmichael

US Patent:

20130150351, Jun 13, 2013

Filed:

Jun 2, 2011

Appl. No.:

13/701448

Inventors:

Stanley T. Carmichael - Sherman Oaks CA, US
Istvan Mody - Los Angeles CA, US
Ben Huang - Los Angeles CA, US
Andrew N. Clarkson - Dunedin, NZ

International Classification:

A61K 31/5517
A61K 31/5513
A61K 31/427
A61K 31/5025
A61K 31/519
A61K 31/454
A61K 31/53

US Classification:

514220, 514219, 514365, 514248, 514243, 514326

Abstract:

Methods for treating a central nervous system (CNS) injury in a subject are provided. As of the methods include administering to the subject an effective amount of gamma aminobutyric acid (GABA) receptor signaling inhibitor to treat the subject for the CNS injury. Also provided are compositions useful in embodiments of the methods. Methods and compositions of the invention find use in the treatment of a variety of different CNS injuries, including but not limited to, treating a subject for CNS injury associated with the occurrence of stroke.

US Patent:

20110224278, Sep 15, 2011

Filed:

Jun 3, 2010

Appl. No.:

12/793607

Inventors:

Stanley T. Carmichael - Sherman Oaks CA, US
Istvan Mody - Los Angeles CA, US
Andrew Clarkson - Los Angeles CA, US
Justine J. Overman - Los Angeles CA, US
Ben Huang - Los Angeles CA, US

International Classification:

A61K 31/713
A61K 31/5517
A61K 31/5025
A61K 31/551
A61P 25/00

US Classification:

514 44 A, 514219, 514220, 514248

Abstract:

Methods for treating a central nervous system (CNS) injury in a subject are provided. Aspects of the methods include administering to the subject an effective amount of gamma aminobutyric acid (GABA) receptor signaling inhibitor to treat the subject for the CNS injury. Also provided are compositions finding use in embodiments of the methods. Methods and compositions of the invention find use in the treatment of a variety of different CNS injuries, including but not limited to, treating a subject for CNS injury associated with the occurrence of stroke.

US Patent:

20210220388, Jul 22, 2021

Filed:

May 10, 2018

Appl. No.:

17/054421

Inventors:

- Oakland CA, US
Stanley Thomas Carmichael - Sherman Oaks CA, US
Lina R. Nih - Redondo Beach CA, US

Assignee:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA

International Classification:

A61K 31/727
A61K 9/14
A61K 9/06
A61K 47/36
A61K 47/18
A61K 47/42
A61P 9/10

Abstract:

A therapeutic hydrogel material includes a hyaluronic acid-based hydrogel matrix containing naked heparin nanoparticles distributed and entrained within the matrix. The naked heparin nanoparticles contained in the matrix are not immobilized to any other molecules at the time of delivery. In one aspect of the invention, the therapeutic hydrogel material is used to repair ischemic tissue in a subject (e.g., mammal). The therapeutic hydrogel material may also be used to treat wounds or other damaged tissue. To treat the subject or patient, the site of application is located and the therapeutic hydrogel material is injected or otherwise delivered (with or without a delivery device) to the delivery location along with a crosslinker.

US Patent:

20140315805, Oct 23, 2014

Filed:

Mar 1, 2012

Appl. No.:

14/003060

Inventors:

Stanley T. Carmichael - Sherman Oaks CA, US
Andrew N. Clarkson - Dunedin, NZ

Assignee:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA

International Classification:

A61K 38/18
A61K 31/445
A61K 31/40
A61K 9/00
A61K 31/727

US Classification:

514 83, 514423, 514330

Abstract:

Methods of improving recovery of a mammal after an ischemic event (e.g., stroke) are provided. In various embodiments the methods involve administering a neural growth factor (e.g., BDNF) into the infarct (e.g., stroke) cavity in a biocompatible hydrogel formulation. In certain embodiments the hydrogel comprises a thiolated hyaluronan and a thiolated gelatin with an optional thiolated heparin.

Address:

70 Marbella, San Clemente, CA 92673

Phone:

9497153761

VIN:

5UXFE83557LZ44353

Make:

BMW

Model:

X5

Year:

2007