Chief Technology Officer (CTO) and Co-founder at Diagnomics, Managing Partner at Genautica, Founder at Corporate Governance Partners
Location:
Greater San Diego Area
Industry:
Venture Capital & Private Equity
Work:
Diagnomics - Greater San Diego Area since Apr 2011
Chief Technology Officer (CTO) and Co-founder
Genautica - Greater Los Angeles Area since Jan 2011
Managing Partner
Corporate Governance Partners - Greater San Diego Area since Nov 2009
Founder
Quadraspec Jun 2008 - Nov 2009
Chief Scientific Officer (CSO)
Corporate Governance Partners Nov 2003 - Jun 2008
Founder
Education:
University of California, San Diego 1989 - 1991
Skills:
Venture Capital Genomics Protein Expression Molecular Biology Cell Biology jQuery HTML 5 CSS3 D3 Proteomics Nanobiotechnology Start-ups Baculovirus Assembly Language Molecular Oncology Systems Biology International Trade Mergers Private Equity Fund Of Funds Mergers & Acquisitions Cleantech Lifesciences Biotechnology R&D Technology Transfer Physics Investments
Honor & Awards:
Friends of Paul Ehrlich Award for the best thesis of the year ("summa cum laude")
Diagnomics - Greater San Diego Area since Apr 2011
Chief Technology Officer (CTO) and Co-founder
Genautica - Greater Los Angeles Area since Jan 2011
Managing Partner
Corporate Governance Partners - Greater San Diego Area since Nov 2009
Founder
Quadraspec Jun 2008 - Nov 2009
Chief Scientific Officer (CSO)
Corporate Governance Partners Nov 2003 - Jun 2008
Founder
Education:
University of California, San Diego 1989 - 1991
Skills:
Venture Capital Start Ups Biotechnology Genomics R&D Mergers and Acquisitions Molecular Biology Private Equity Entrepreneurship Corporate Development Technology Transfer Bioinformatics Commercialization Cell Biology Cancer Science Lifesciences Executive Management Investments Licensing International Trade Global Business Development Protein Chemistry Mergers Systems Biology Emerging Markets Strategic Consulting Protein Expression Proteomics Dna Sequencing M&A Experience Nanobiotechnology Nanotechnology Biomedical Engineering Fund of Funds Physics Start Up Ventures Joint Ventures Turn Around Management Innovation Management Baculovirus Biopharmaceuticals Technology Evaluation Jquery Html 5 Css3 Python Assembly Language Molecular Oncology Cleantech
Interests:
Science and Technology
Languages:
German English
Certifications:
Data Analysis In Python With Pandas (Link) Data Analysis In Python With Pandas Udemy
Us Patents
Flow Cytometric Methods For The Concurrent Detection Of Discrete Functional Conformations Of Prb In Single Cells
Zbigniew Darzynkiewicz - Chappaque NY Frank Traganos - New York NY Gloria Juan - Sleepy Hollow NY Stefan Gruenwald - Encinitas CA
Assignee:
Becton, Dickinson and Company - Franklin Lakes NJ
International Classification:
G01N 33574
US Classification:
435 72, 435 721, 435 723, 435 724, 435 74, 436800
Abstract:
Methods, reagents, and kits are provided that permit flow cytometric determination of the phosphorylation status of retinoblastoma susceptibility gene protein (pRB) in individual cells. Methods are described that permit the hypophosphorylated, active, form of pRB to be measured either as an absolute quantity or as a proportion of total cellular pRB. Further described are methods that permit pRB phosphorylation status to be correlated with cell cycle phase and with protein components of the cell cycle. Screening of chemical compounds for antiproliferative and antineoplastic activity using the flow cytometric assays is demonstrated. Reagent kits that facilitate the subject methods are also provided.
Detection Of Protein Conformations In Single Cells
Methods, reagents, and kits are provided that permit flow cytometric determination of the phosphorylation status of retinoblastoma susceptibility gene protein (pRB) in individual cells. Methods are described that permit the hypophosphorylated, active, form of pRB to be measured either as an absolute quantity or as a proportion of total cellular pRB. Further described are methods that permit pRB phosphorylation status to be correlated with cell cycle phase and with protein components of the cell cycle. Screening of chemical compounds for antiproliferative and antineoplastic activity using the flow cytometric assays is demonstrated. Reagent kits that facilitate the subject methods are also provided.
E2A/Pbx1 Fusion Protein Specific Monoclonal Antibodies
Johann Wolfgang Goethe University of Frankfurt am Main - Medicine, Johann Wolfgang Goethe University of Frankfurt am Main - Protein Chemistry, Scripps, La Jolla - Immunology, UCSD - Molecular Biology