Richard B. Roth - La Jolla CA, US Matthew Roberts Nelson - San Marcos CA, US Stefan M. Kammerer - San Diego CA, US Andreas Braun - San Diego CA, US Rikard Reneland - San Diego CA, US
Assignee:
Sequenom, Inc. - San Diego CA
International Classification:
C12Q 1/68 C12P 19/34 C07H 21/04 C07H 21/02
US Classification:
435 6, 435 911, 435 912, 536 231, 536 243
Abstract:
Provided herein are methods for identifying risk of breast cancer in a subject and/or a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
Kinase Anchor Protein Muteins, Peptides Thereof And Related Documents
Andreas Braun - San Diego CA, US Charles Cantor - Del Mar CA, US Stefan Kammerer - San Diego CA, US Susan Taylor - Del Mar CA, US Charles Cook - Mendham NJ, US Gary Olson - Mountainside NJ, US Christopher Self - West Caldwell NJ, US
A-kinase anchor protein (AKAPs) muteins, peptides thereof, and nucleic acids encoding the peptides are provided herein. Also provided are transgenic animals, cells comprising transgenes and various methods employing such peptides.
Methods For Identifying Risk Of Breast Cancer And Treatments Thereof
Richard Roth - La Jolla CA, US Matthew Nelson - San Marcos CA, US Stefan Kammerer - San Diego CA, US Andreas Braun - San Diego CA, US Rikard Reneland - San Diego CA, US
International Classification:
C12Q001/68
US Classification:
435006000
Abstract:
Provided herein are methods for identifying risk of breast cancer in a subject and/or a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
Methods For Identifying Risk Of Melanoma And Treatments Thereof
Richard Roth - La Jolla CA, US Matthew Nelson - San Marcos CA, US Stefan Kammerer - San Diego CA, US Andreas Braun - San Diego CA, US
International Classification:
C12Q001/68
US Classification:
435006000
Abstract:
Provided herein are methods for identifying a subject at risk of melanoma and risk of melanoma in a subject, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating melanoma, and therapeutic methods for treating melanoma in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
Methods For Identifying Risk Of Breast Cancer And Treatments Thereof
Richard Roth - La Jolla CA, US Josephine Atienza - La Jolla CA, US Mikhail Denissenko - Poway CA, US Andreas Braun - San Diego CA, US Stefan Kammerer - San Diego CA, US Matthew Nelson - San Marcos CA, US Rikard Reneland - San Diego CA, US
International Classification:
C12Q001/68 G01N033/574
US Classification:
435006000, 435007230
Abstract:
Provided herein are methods for identifying a subject at risk of breast cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating breast cancer, and therapeutic methods for treating breast cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in nucleotide sequences within the human genome.
Methods For Identifying Risk Of Melanoma And Treatments Thereof
Provided herein are methods for identifying risk of melanoma in a subject and/or subjects at risk of melanoma, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating melanoma, therapeutic methods for treating melanoma in a subject and compositions comprising one or more melanoma cells and one or more NRP1, NID2 or ENDO180 directed agents. These embodiments are based upon an analysis of polymorphic variations in a NRP1, NID2 or ENDO180 nucleic acid, exemplified by nucleotide sequences of SEQ ID NO: 1, 2 or 3.
Methods For Identifying Risk Of Breast Cancer And Treatments Thereof
Richard Roth - La Jolla CA, US Caridad Rosette - San Diego CA, US Mikhail Denissenko - Poway CA, US Matthew Nelson - San Marcos CA, US Rikard Reneland - San Diego CA, US Andreas Braun - San Diego CA, US Stefan Kammerer - San Diego CA, US
International Classification:
C12Q001/68 A61K048/00
US Classification:
435006000, 514044000
Abstract:
Provided herein are methods for identifying a risk of cancer in a subject and/or a subject at risk of cancer, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating cancer, and therapeutic methods for treating cancer in a subject. These embodiments are based upon an analysis of polymorphic variations in a KLF12 nucleic acid, which has a nucleotide sequence exemplified in SEQ ID NO: 1, 2 or 3.
Methods For Identifying Risk Of Melanoma And Treatments Thereof
Richard Roth - La Jolla CA, US Matthew Nelson - San Marcos CA, US Stefan Kammerer - San Diego CA, US Andreas Braun - San Diego CA, US
International Classification:
C12N005/06
US Classification:
435344100
Abstract:
Provided herein are methods for identifying risk of melanoma in a subject and/or subjects at risk of melanoma, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating melanoma, therapeutic methods for treating melanoma in a subject and compositions comprising one or more melanoma cells and one or more CDK10, FPGT, PCLO or REPS2 directed agents. These embodiments are based upon an analysis of polymorphic variations in a CDK10, FPGT, PCLO or REPS2 nucleic acid, exemplified by nucleotide sequences of SEQ ID NO: 1, 2, 3 or 4.
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