Stephane Peluso from 38 Algonquian Dr, Natick, MA 01760, age 54

Us Patents

Cyclopamine Analogs
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US Patent:

7812164, Oct 12, 2010
Filed:

Dec 27, 2007
Appl. No.:

11/965688
Inventors:

Brian Austad - Tewksbury MA, US
Mark L. Behnke - Somerville MA, US
Alfredo C. Castro - Winchester MA, US
Michael J. Grogan - Winchester MA, US
Andre Lescarbeau - Somerville MA, US
Stephane Peluso - Somerville MA, US
Martin Tremblay - Melrose MA, US
Assignee:

Infinity Pharmaceuticals, Inc. - Cambridge MA
International Classification:

C07D 401/00
C07D 515/02
US Classification:

546 17, 546115, 549331, 549345
Abstract:

The invention provides novel derivatives of cyclopamine having the following formula:.

Compounds And Methods For Inhibiting The Interaction Of Bcl Proteins With Binding Partners
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US Patent:

7928244, Apr 19, 2011
Filed:

Aug 21, 2007
Appl. No.:

11/842581
Inventors:

Alfredo C. Castro - Winchester MA, US
Kristopher M. Depew - Acton MA, US
Michael J. Grogan - Winchester MA, US
Charles W. Johannes - Newbury MA, US
Edward B. Holson - Newton Highlands MA, US
Brian T. Hopkins - Newton MA, US
Gregg F. Keaney - Belmont MA, US
Nii O. Koney - Brighton MA, US
Tao Liu - Ashland MA, US
David A. Mann - Swampscott MA, US
Marta Nevalainen - Quincy MA, US
Stephane Peluso - Somerville MA, US
Lawrence B. Perez - Hopkinton MA, US
Daniel A. Snyder - Somerville MA, US
Thomas T. Tibbitts - Westford MA, US
Assignee:

Infinity Discovery, Inc. - Cambridge MA
International Classification:

C07D 261/02
A61K 31/42
US Classification:

548240, 514378
Abstract:

The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer.

Substituted Pyrrolo[2,3-D]Pyrimidines As Inhibitors Of E1 Activating Enzymes
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US Patent:

7951810, May 31, 2011
Filed:

Feb 2, 2006
Appl. No.:

11/346469
Inventors:

Stephen Critchley - Braintree MA, US
Thomas G. Gant - Carlsbad CA, US
Steven P. Langston - North Andover MA, US
Edward J. Olhava - Brookline MA, US
Stephane Peluso - Somerville MA, US
Assignee:

Millennium Pharmaceuticals, Inc. - Cambridge MA
International Classification:

C07D 487/04
A61K 31/519
A61P 35/00
A61P 25/28
A61P 29/00
US Classification:

5142651, 544280
Abstract:

This invention relates to compounds of formula (I-A).

Heteroaryl Compounds Useful As Inhibitors Of E1 Activating Enzymes
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US Patent:

8008307, Aug 30, 2011
Filed:

Aug 6, 2007
Appl. No.:

11/890338
Inventors:

Christopher F. Claiborne - Cambridge MA, US
Stephen Critchley - Braintree MA, US
Courtney Cullis - Bedford MA, US
Steven P. Langston - North Andover MA, US
Hirotake Mizutani - Cambridge MA, US
Edward J. Olhava - Cambridge MA, US
Stephane Peluso - Somerville MA, US
Irache Visiers - Arlington MA, US
Stepan Vyskocil - Watertown MA, US
Gabriel S. Weatherhead - Salem MA, US
Assignee:

Millennium Pharmaceuticals, Inc. - Cambridge MA
International Classification:

C07D 239/48
A61K 31/505
US Classification:

514256, 5142651, 514269, 514275, 544280, 544319, 544323, 544327
Abstract:

This invention relates to compounds that inhibit E1 activating enzymes, pharmaceutical compositions comprising the compounds, and methods of using the compounds. The compounds are useful for treating disorders, particularly cell proliferation disorders, including cancers, inflammatory and neurodegenerative disorders; and inflammation associated with infection and cachexia.

Compounds And Methods For Inhibiting The Interaction Of Bcl Proteins With Binding Partners
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US Patent:

8178690, May 15, 2012
Filed:

Apr 19, 2011
Appl. No.:

13/089530
Inventors:

Alfredo C. Castro - Winchester MA, US
Kristopher M. Depew - Acton MA, US
Michael J. Grogan - Winchester MA, US
Charles W. Johannes - Newbury MA, US
Edward B. Holson - Newton Highlands MA, US
Brian T. Hopkins - Newton MA, US
Gregg F. Keaney - Belmont MA, US
Nii O. Koney - New York NY, US
Tao Liu - Ashland MA, US
David A. Mann - Madison WI, US
Marta Nevalainen - Quincy MA, US
Stephane Peluso - Somerville MA, US
Lawrence Blas Perez - Hopkinton MA, US
Daniel A. Snyder - Somerville MA, US
Thomas T. Tibbitts - Westford MA, US
Assignee:

Infinity Pharmaceuticals, Inc. - Cambridge MA
International Classification:

C07D 261/02
A61K 31/42
US Classification:

548240, 514378
Abstract:

The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer.

Compounds And Methods For Inhibiting The Interaction Of Bcl Proteins With Binding Partners
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US Patent:

8304428, Nov 6, 2012
Filed:

Apr 2, 2010
Appl. No.:

12/753319
Inventors:

Alfredo C. Castro - Winchester MA, US
Michael J. Grogan - Winchester MA, US
Edward B. Holson - Newton Highlands MA, US
Brian T. Hopkins - Newton MA, US
Nii O. Koney - New York NY, US
Stephane Peluso - Somerville MA, US
Daniel A. Snyder - Somerville MA, US
Assignee:

Infinity Discovery, Inc. - Cambridge MA
International Classification:

A61K 31/445
US Classification:

514315, 514365, 514423
Abstract:

The present invention relates to heterocyclic compounds that bind to Bcl proteins and inhibit Bcl function, compositions comprising such compounds, and methods for treating and modulating disorders associated with hyperproliferation, such as cancer.

Triazoles As Inhibitors Of Fatty Acid Synthase
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US Patent:

8450350, May 28, 2013
Filed:

May 5, 2011
Appl. No.:

13/101970
Inventors:

Adilah Bahadoor - Cambridge MA, US
Alfredo C. Castro - Winchester MA, US
Lawrence K. Chan - Brookline MA, US
Gregg F. Keaney - Lexington MA, US
Marta Nevalainen - Weymouth MA, US
Vesa Nevalainen - Weymouth MA, US
Stephane Peluso - Brookline MA, US
Thomas T. Tibbitts - Westford MA, US
Assignee:

Infinity Pharmaceuticals, Inc. - Cambridge MA
International Classification:

A61K 31/41
A61K 31/4192
C07D 249/00
C07D 249/06
US Classification:

514359, 548255
Abstract:

Provided herein are triazole FASN inhibitors of the formula (I):Also provided herein are pharmaceutical compositions of the compounds provided herein as well as methods of their use for the treatment of various disorders such as hyperproliferative disorders, inflammatory disorders, obesity-related disorders and microbial infections.

Heteroaryl Compounds Useful As Inhibitors Of E1 Activating Enzymes
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US Patent:

8481550, Jul 9, 2013
Filed:

Aug 24, 2011
Appl. No.:

13/216352
Inventors:

Christopher F. Claiborne - Cambridge MA, US
Stephen Critchley - Braintree MA, US
Courtney A. Cullis - Bedford MA, US
Steven P. Langston - North Andover MA, US
Hirotake Mizutani - Cambridge MA, US
Edward J. Olhava - Newton MA, US
Stephane Peluso - Somerville MA, US
Irache Visiers - Arlington MA, US
Stepan Vyskocil - Arlington MA, US
Gabriel S. Weatherhead - Tewksbury MA, US
Assignee:

Millennium Pharmaceuticals, Inc. - Cambridge MA
International Classification:

A61K 31/505
C07D 239/48
US Classification:

514256, 5142651, 514269, 514275, 544280, 544319, 544323, 544327
Abstract:

This invention relates to compounds that inhibit E1 activating enzymes, pharmaceutical compositions comprising the compounds, and methods of using the compounds. The compounds are useful for treating disorders, particularly cell proliferation disorders, including cancers, inflammatory and neurodegenerative disorders; and inflammation associated with infection and cachexia.

Stephane Peluso

Stephane Peluso Phones & Addresses

Us Patents

Cyclopamine Analogs

Compounds And Methods For Inhibiting The Interaction Of Bcl Proteins With Binding Partners

Substituted Pyrrolo[2,3-D]Pyrimidines As Inhibitors Of E1 Activating Enzymes

Heteroaryl Compounds Useful As Inhibitors Of E1 Activating Enzymes

Compounds And Methods For Inhibiting The Interaction Of Bcl Proteins With Binding Partners

Compounds And Methods For Inhibiting The Interaction Of Bcl Proteins With Binding Partners

Triazoles As Inhibitors Of Fatty Acid Synthase

Heteroaryl Compounds Useful As Inhibitors Of E1 Activating Enzymes

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