Stephen H Chang

age ~70

from Floral Park, NY

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Stephen Chang Phones & Addresses

English

Healthgrades Honor Roll

Diagnostic Radiology

Microglia Derived From Pluripotent Stem Cells And Methods Of Making And Using The Same
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US Patent:

20210403863, Dec 30, 2021
Filed:

Sep 13, 2021
Appl. No.:

17/473257
Inventors:

- New York NY, US
Scott Noggle - New Rochelle NY, US
Stephen Chang - Poway CA, US
Valentina Fossati - New York NY, US
International Classification:

C12N 5/079
C12N 5/0735
A61K 35/30
G01N 33/50
Abstract:

The present invention provides methods and compositions for the generation of microglial progenitor cells and microglial cells from pluripotent stem cells, such as embryonic stem cells and induced pluripotent stem cells. The present invention also provides cells produced using such methods, and both methods of treatment and methods of drug screening that use such cells. Also provided are various tissue culture media, tissue culture media supplements, and kits useful for the generation of human microglial progenitor cells and human microglial cells.

Microfluidic System And Method Of Use Thereof
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US Patent:

20190316075, Oct 17, 2019
Filed:

Nov 17, 2017
Appl. No.:

16/462047
Inventors:

- New York NY, US
Stephen Chang - New York NY, US
International Classification:

C12M 1/00
G01N 15/02
F16K 99/00
B01L 3/00
Abstract:

This invention concerns an integrated microfluidic system that utilizes microfluidic chip technology to receive a patient sample including cells, expand the cells, reprogram the expanded cells and then store the reprogrammed cells in a microfluidic chip. These microfluidic chips with stored reprogrammed cells may then be used in scenarios of genetic differentiation into specific cell types. Overall this system and workflow is suitable as a hospital based device that will allow the generation of iPSCs from every isolating patient for downstream diagnostic or therapeutic use.

Microglia Derived From Pluripotent Stem Cells And Methods Of Making And Using The Same
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US Patent:

20170253856, Sep 7, 2017
Filed:

Mar 3, 2017
Appl. No.:

15/449519
Inventors:

Panagiotis Douvaras - New York NY, US
Scott Noggle - Long Island City NY, US
Stephen Chang - New York NY, US
Valentina Fossati - New York NY, US
International Classification:

C12N 5/079
G01N 33/50
A61K 35/30
Abstract:

The present invention provides methods and compositions for the generation of microglial progenitor cells and microglial cells from pluripotent stem cells, such as embryonic stem cells and induced pluripotent stem cells. The present invention also provides cells produced using such methods, and both methods of treatment and methods of drug screening that use such cells. Also provided are various tissue culture media, tissue culture media supplements, and kits useful for the generation of human microglial progenitor cells and human microglial cells.

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Author
Stephen Chang

ISBN #
0890871248

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Author
Stephen S. Chang

ISBN #
0935315241

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Author
Stephen Thomas Chang

ISBN #
0894070177

Name / Title

Company / Classification

Phones & Addresses

Stephen Chang
Chairman

Grid Design Inc.
Commercial Art and Graphic Design

160 5Th Ave, New York, NY 10010

Stephen Chang
COO