Donald Wise - Belmont MA, US Debra Trantolo - Princeton MA, US David Hile - Medford MA, US Stephen Doherty - Newmarket NH, US
Assignee:
Cambridge Scientific, Inc.
International Classification:
A61K039/02 A61K039/002 A61K009/16 A61K009/50
US Classification:
424/190100, 424/191100, 424/490000
Abstract:
A bioadhesive mucosal delivery system is used in concert with systemic immunization to develop long-lasting immune responses correlative to protective immunity, especially for the prevention of infection with malaria, tularemia, anthrax, and First, the method provides controlled delivery of protective antigens, such as ODNs, to a mucosal site resulting in “priming” of mucosal receptors. Second, the method augments this mucosal prime with parenteral stimulation. In another embodiment, an intranasal vaccine is used in the treatment of tularemia and other bacterial and viral inhalation antigens. The use of CpG motifs in bacterial DNA allows for the activation of the innate immune response that is characterized by the production of immunostimulatory cytokines and polyreactive antibodies. The rapid response system limits the spread of the pathogen prior to specific immunity activation. The use of sustained mucosal exposure lowers the activation threshold of the innate immune system, allowing for a stronger and more rapid response to infection.
Apr 2010 to 2000 Call Firefighter / EMT / DiverAccubit
Aug 2003 to 2000 Sales & MarketingFreelance
Sep 2001 to 2000 Designer/ConsultantAnalytX Inc. Boston, MA Jan 2002 to Feb 2003 Assistant to the ControllerMorris Media Enterprises Savannah, GA Nov 1999 to Aug 2001 Art Director
Education:
Savannah College of Art and Design Savannah, GA 1996 to 2000 B.F.A., School of Communication Arts in Graphic Design
Skills:
Proficient on both Mac and PC Platforms, Adobe Creative Suite Applications (Photoshop, Illustrator, InDesign, DreamWeaver, Flash, Acrobat), QuarkXpress, IMovieMicrosoft Office (Excel, Word, PowerPoint, and Access), WordPress, ContactPlus Professional, Constant Contact, Salesforce.com
spokesman, Stephen Doherty, declined to discuss the persons case, citing medical privacy, but said the Postal Service has followed all appropriate protocols and precautions in consultation with postal occupational health administrators and local health officials in keeping with CDC standards.
"If you use Bitcoins, you have the option to encrypt your wallet and we recommend that you choose a strong password for this in the event that an attacker is attempting to brute-force your wallet open," Symantec's Stephen Doherty said.
Date: Jun 17, 2011
Category: Sci/Tech
Source: Google
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