George H. Searfoss - Birdsboro PA Yuri D. Ivashchenko - Audubon PA Michael C. Jaye - Glenside PA Victoria J. South - Audubon PA Stephen M. French - Phoenixville PA Christopher Cheadle - West Chester PA George A. Ricca - Blue Bell PA
Assignee:
Rhone-Poulenc Rorer Pharmaceuticals Inc. - Collegeville PA
International Classification:
C12N 120 C12N 1563 C07H 2104
US Classification:
4352523
Abstract:
This invention provides a unique SH3 binding domain core motif of the sequence RPLPXXP and cDNA clones encoding proteins which interact with the SH3 domain of c-src, as well as the amino acid sequences which mediate this binding. Another embodiment of this invention is a method of identifying SH3-binding proteins and elucidating the sequences which mediate binding. This method may be used as an assay to select compounds which bind to this site and which inhibit or enhance the binding of the SH3 domain.
License Records
Stephen Murray French
Address:
Allentown, PA 18104
License #:
PE044641E - Active
Category:
Engineers
Type:
Professional Engineer
Googleplus
Stephen French
Work:
Metron Aviation - Systems Engineer USMC Hughes Training, Inc. SAIC EG&G BAE Systems FAA
Education:
Irvine High School, San Diego State University, Officer Candidate School (USMC), The Basic School (USMC), Flight School (USMC NFO), Navy Postgraduate School (Aviation Safety)
Raleigh, NCDirector, Global Marketing at Tekelec Past: Sr. Manager, Product Management at Hatteras Networks, Sr. Manager, Global Solutions... I grew up in the Saratoga, NY area. After college I flew jets in the Navy, and then settled in Raleigh, NC for a recruiting job & grad school. For the last 10+... I grew up in the Saratoga, NY area. After college I flew jets in the Navy, and then settled in Raleigh, NC for a recruiting job & grad school. For the last 10+ years I've done product management and marketing for several technology firms.