Michael Weiner - Guilford CT, US Said Attiya - Branford CT, US Hugh Crenshaw - Durham NC, US Jonathan Rothberg - Guilford CT, US Stephen Matson - Harvard MA, US
International Classification:
C12Q001/68 C12M001/34
US Classification:
435006000, 435287200
Abstract:
The present invention relates to the field of fluid dynamics. More specifically, this invention relates to methods and apparatus for conducting densely packed, independent chemical reactions in parallel in a substantially two-dimensional array. Accordingly, this invention also focuses on the use of this array for applications such as DNA sequencing, most preferably pyrosequencing, and DNA amplification.