Stephen P Russell

US Patent:

20020043180, Apr 18, 2002

Filed:

Aug 30, 2001

Appl. No.:

09/942022

Inventors:

Andrew Bayliff - Lancashire, GB
Frank Andrews - Kent, GB
Gary Latto - Willowbrook IL, US
Stephen Russell - Grayslake IL, US

International Classification:

C08L091/06

US Classification:

106/270000

Abstract:

A wax-based composition for repairing defects in underground pipes in situ. The composition comprises wax and a dewetting agent. The dewetting agent is preferably an ethoxylated acetylenic diol.

US Patent:

20050272643, Dec 8, 2005

Filed:

Jun 8, 2004

Appl. No.:

10/862879

Inventors:

Henry Brzeski - Johnstown PA, US
Stephen Russell - Johnstown PA, US

Assignee:

Windber Research Institute - Windber PA

International Classification:

A61K038/38
C07K014/765

US Classification:

514008000, 530363000

Abstract:

A method of removing serum albumin from blood serum or plasma includes contacting the blood serum or plasma with a sugar-binding protein such as a lectin (e.g., Concanavalin A or wheat germ agglutinin) immobilized on an insoluble support such as a porous bead (e.g., agarose). The method may be practiced by immobilizing a sugar-binding protein on an insoluble support, preparing blood serum or plasma for contacting with the insoluble support having the sugar-binding protein immobilized thereon, contacting the prepared blood serum or plasma with the insoluble support having the sugar-binding protein immobilized thereon to absorb glycosylated proteins from the blood serum or plasma leaving an unbound fraction containing serum albumin, and differentially eluting glycosylated proteins with different sugars from the insoluble support contacted with the blood serum or plasma.

US Patent:

20100216177, Aug 26, 2010

Filed:

Feb 20, 2009

Appl. No.:

12/389563

Inventors:

Richard Idem Somiari - Johnstown PA, US
Stella Bassey Somiari - Johnstown PA, US
Stephen Russell - Johnstown PA, US

Assignee:

ITSI Biosciences - Johnstown PA

International Classification:

C12Q 1/37

US Classification:

435 23

Abstract:

A method of assessing enzyme function or protein stability is disclosed. A sample having a protein therein is contacted with an enzyme that is suspected of being capable of catalyzing digestion of the protein in order to form a mixture. First and second aliquots are removed from the mixture at first and second times, respectively, and protein digestion is evaluated using a detection reagent to calculate a change in absorbance between first and second aliquots. The change in absorbance provides an index of enzyme activity, enzyme capability, and protein stability.

US Patent:

20210046134, Feb 18, 2021

Filed:

Apr 12, 2019

Appl. No.:

16/980359

Inventors:

- Rochester MN, US
Karol M. Budzik - Mount Prospect IL, US
Stephen James Russell - Rochester MN, US

International Classification:

A61K 35/768
C12N 7/00
A61P 35/00

Abstract:

This document provides methods and materials for treating cancer. For example, foamy viruses (e.g., simian foamy viruses) are provided as well as methods and materials for treating cancer using foamy viruses as an oncolytic agent.

US Patent:

20170015939, Jan 19, 2017

Filed:

Sep 29, 2016

Appl. No.:

15/279863

Inventors:

- WAYZATA MN, US
Stephen E. Russell - Grayslake IL, US

International Classification:

C11C 5/00
C11C 5/02

Abstract:

Lipid-based wax compositions and their methods of making are provided for compositions substantially free of fat bloom. The compositions comprise 0.1-10 percent by weight triacylglycerides, 30-95 percent by weight monoacylglycerides and diacylglycerides combined, and 0.1-65 percent by weight fatty acids. The methods comprise blending the monoacylglycerides, diacylglycerides, triacylglycerides, and fatty acids by heating the lipid-based wax composition at a sufficiently high temperature to destroy substantially all crystal structure within the lipid-based wax composition. The methods further comprise pouring the lipid-based wax composition into a mold or a container having a surface and a core, wherein the pouring is conducted at a temperature at least 15 C. greater than the congeal point of the lipid-based wax composition. The methods further comprise cooling the lipid-based wax composition under conditions sufficient to cool the core to at least 5 C. below the congeal point of the lipid-based wax composition in 30-90 minutes.