Stephen L Schafer

US Patent:

20220323587, Oct 13, 2022

Filed:

Jun 28, 2022

Appl. No.:

17/851447

Inventors:

- Austin TX, US
Stephen Clay SCHAFER - Austin TX, US

Assignee:

BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM - Austin TX

International Classification:

A61K 47/26
A61K 9/00
A61K 9/70
A61K 47/18
A61K 47/34
C07K 16/38

Abstract:

Disclosed herein are compositions and methods for storing biologically active polypeptides. When the biologically active polypeptides are formulated appropriately within the compositions, they can be stored at room temperature for extended periods of time and retain a significant amount of activity prior to storage. Examples of the activity that is retained is at least about 70% to 95% activity prior to storage. Duration of storage may be for extended amounts of time, for example 1 week, 2 weeks, 1 month, 2 months, 4 months, 6 months, 8 months, or longer than a year. Methods for administering, formulating and stabilizing the biologically active polypeptides are also disclosed.

US Patent:

20200353068, Nov 12, 2020

Filed:

Jul 28, 2020

Appl. No.:

16/941481

Inventors:

- Austin TX, US
Stephen Clay SCHAFER - Austin TX, US

International Classification:

A61K 39/12
C12N 7/00
A61K 39/39
C12N 15/88

Abstract:

Immunogenic compositions comprising viral vectors and surfactants are provided. Methods for administration and preparation of such compositions are also provided.

US Patent:

20200237649, Jul 30, 2020

Filed:

Apr 10, 2020

Appl. No.:

16/845930

Inventors:

- Austin TX, US
Jin Huk CHOI - Austin TX, US
Stephen Clay Schafer - Austin TX, US

International Classification:

A61K 9/00
A61K 47/26
C12N 7/00
C12N 1/04
A61K 39/12

Abstract:

Vaccine compositions that may be administered to a subject via the buccal and/or sublingual mucosa are provided. Methods for administration and preparation of such vaccine compositions are also provided.

US Patent:

20190314480, Oct 17, 2019

Filed:

Apr 23, 2019

Appl. No.:

16/392137

Inventors:

- Austin TX, US
Stephen Clay SCHAFER - Austin TX, US

International Classification:

A61K 39/12
C12N 15/88
A61K 39/39
C12N 7/00

Abstract:

Immunogenic compositions comprising viral vectors and surfactants are provided. Methods for administration and preparation of such compositions are also provided.

US Patent:

20190298836, Oct 3, 2019

Filed:

Nov 2, 2017

Appl. No.:

16/346529

Inventors:

- Austin TX, US
Stephen Clay SCHAFER - Austin TX, US

International Classification:

A61K 47/26
A61K 9/00
A61K 9/70
A61K 47/34
A61K 47/18
C07K 16/38

Abstract:

Soluble film compositions comprising biologically active polypeptides are provided, which stabilize the polypeptides. Methods for administering, formulating and stabilizing polypeptides are also provided.

US Patent:

20180326036, Nov 15, 2018

Filed:

Feb 27, 2018

Appl. No.:

15/907259

Inventors:

- Austin TX, US
Stephen Clay SCHAFER - Austin TX, US

International Classification:

A61K 39/12
C12N 15/88

Abstract:

Immunogenic compositions comprising viral vectors and surfactants are provided. Methods for administration and preparation of such compositions are also provided.

US Patent:

20180000724, Jan 4, 2018

Filed:

May 10, 2017

Appl. No.:

15/591725

Inventors:

- Austin TX, US
Jin Huk CHOI - Austin TX, US
Stephen Clay Schafer - Austin TX, US

International Classification:

A61K 9/00
A61K 39/12
C12N 7/00
C12N 1/04
A61K 47/26
A61K 39/00

Abstract:

Vaccine compositions that may be administered to a subject via the buccal and/or sublingual mucosa are provided. Methods for administration and preparation of such vaccine compositions are also provided.

US Patent:

20160296616, Oct 13, 2016

Filed:

Mar 25, 2016

Appl. No.:

15/081601

Inventors:

- Austin TX, US
Stephen Clay SCHAFER - Austin TX, US

International Classification:

A61K 39/12
C12N 7/00

Abstract:

Immunogenic compositions comprising viral vectors and surfactants are provided. Methods for administration and preparation of such compositions are also provided.