Stephen E Webber

US Patent:

59555092, Sep 21, 1999

Filed:

Apr 23, 1997

Appl. No.:

8/842207

Inventors:

Stephen E. Webber - Austin TX
Thomas J. Martin - Cedar Park TX

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

A61K 4734
C08G 6800

US Classification:

5147727

Abstract:

The present invention relates to the use of poly(vinyl N-heterocycle)-block-poly(alkylene oxide) copolymers in micelle containing pharmaceutical formulations. The copolymers advantageously respond to pH differences in the environment to which they are exposed forming micelles at higher pH values. The micelles, which comprise a therapeutic compound and a copolymer, deliver drug in a pH dependent manner.

US Patent:

52722406, Dec 21, 1993

Filed:

May 29, 1991

Appl. No.:

7/707140

Inventors:

Yair Haruvy - Austin TX
Stephen E. Webber - Austin TX

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

C08G 7706

US Classification:

528 10

Abstract:

The present invention relates to a method of preparing glasses from metal alkoxides. Glasses are crack-free and prepared rapidly in a single step. Optically clear polysiloxane glasses as thin films may be prepared in a matter of minutes. A glow discharge curing method is disclosed which rapidly cures a wide range of condensation polymers, including polyamide resins and polymethylsiloxane glass films. Fracture-free films up to 100. mu. m have been prepared. The glass films may be used as waveguides and to incorporate metals, donor-acceptor molecules and dyes. Stable, crack-free multiple-layered films may be prepared by the disclosed method which can be modified according to desired properties of the glasses.

US Patent:

53570154, Oct 18, 1994

Filed:

Mar 10, 1993

Appl. No.:

8/028786

Inventors:

Yair Haruvy - Rehovot, IL
Stephen E. Webber - Austin TX

Assignee:

Board of Regents, The University of Texas - Austin TX

International Classification:

C08G 7706

US Classification:

528 10

Abstract:

The present invention relates to methods of accelerated curing of condensation polymers or inducing cross-linking of polymers by a direct current corona or glow discharge applied to the polymer bulk. The methods permit low temperature removal of volatile components from a material without inducing a chemical reaction or local heating. These methods have been employed to prepare fracture-free polysiloxane films up to 100. mu. m in thickness with curing time reduced by several orders of magnitude. A variety of metal ions, non-linear optical molecules or laser dyes may be incorporated in the films. The surface hydrophilicity of films may also be modified by this treatment. Additionally, an electrically conductive surface layer has been produced by incorporation of an appropriate dopant. Multilayered optical waveguide or lasing structures may be produced by this technique by successive deposition of spun films and curing.