Steven I Baskin

US Patent:

7371714, May 13, 2008

Filed:

Jun 22, 2006

Appl. No.:

11/472434

Inventors:

David S. Johnston - Gunpowder MD, US
Gennady E. Platoff - Millersville MD, US
Steven I. Baskin - Bel Air MD, US
Thomas P. Logan - Bel Air MD, US

Assignee:

The United States of America as represented by the Secretary of the Army - Washington DC

International Classification:

C11D 3/24
C11D 3/395

US Classification:

510110, 510273, 510375, 510204

Abstract:

A composition and methods of use for the decontamination of chemical agents, including chemical warfare agents. The decontamination composition is nontoxic, nonflammable and non-corrosive and includes an effective amount of a perfluorinated alkyl bromide or reactive perfluorinated alkyl bromide. The decontamination composition may include an oxidizer and a solvent.

US Patent:

20090117207, May 7, 2009

Filed:

Nov 29, 2005

Appl. No.:

11/288268

Inventors:

Csaba K. Zoltani - Lutherville MD, US
Gennady E. Platoff - Millersville MD, US
Steven I. Baskin - Bel Air MD, US

International Classification:

A61K 31/185
A61K 31/16
A61K 31/138
A61K 31/44
A61K 31/195
A61K 33/00
A61K 33/04
A61P 9/00
A61K 31/4375

US Classification:

424699, 514710, 514625, 514648, 514352, 514567, 424708, 424718, 514279

Abstract:

A method of treating a poison-caused pathology in an individual subject is described which includes administering a pharmaceutical composition including a therapeutically effective amount of a chloride current modulator, a therapeutically effective amount of an exogenous oxygen carrier, or a combination of a therapeutically effective amount of a chloride current modulator and a therapeutically effective amount of an exogenous oxygen carrier, to an individual subject exposed to a poison. Optionally, an inventive method further includes administering a therapeutic agent to inhibit poison-caused pathology. A composition according to the invention is described which includes a therapeutically effective amount of a chloride current modulator, a therapeutically effective amount of an exogenous oxygen carrier, or a combination of a therapeutically effective amount of a chloride current modulator and a therapeutically effective amount of an exogenous oxygen carrier. Further included in one embodiment is a therapeutic agent to inhibit poison-caused pathology.

US Patent:

20100168030, Jul 1, 2010

Filed:

Nov 29, 2005

Appl. No.:

11/288269

Inventors:

Csaba K. Zoltani - Lutherville MD, US
Gennady E. Platoff - Millersville MD, US
Steven I. Baskin - Bel Air MD, US

International Classification:

A61K 38/16
A61P 9/06

US Classification:

514 13

Abstract:

A method of treating an organophosphate toxin-caused cardiac abnormality is described which includes administering a pharmaceutical composition including a therapeutically effective amount of a chloride current modulator to an individual subject having a cardiac abnormality caused by intoxication with an organophosphate toxin. The chloride current modulator is effective to modulate a chloride conductance and thereby reduce a symptom or sign of an organophosphate toxin-caused cardiac abnormality, thus treating the toxin-caused cardiac abnormality. Optionally, included is administering a therapeutic agent to inhibit an organophosphate toxin-caused distortion of the action potential of myocytes, support restoration of usual intracellular ionic concentrations, and support an increase in cardiac contractility. A composition according to the invention is described which includes a chloride current modulator; and a therapeutic agent to inhibit an organophosphate toxin-induced distortion of the action potential of myocytes, support restoration of usual intracellular ionic concentrations, and support an increase in cardiac contractility.

US Patent:

20120164738, Jun 28, 2012

Filed:

May 5, 2008

Appl. No.:

12/115460

Inventors:

James B. Kelly - Fredericksburg VA, US
Fred M. Hawkridge - Powhatan VA, US
Steven I. Baskin - Bel Air MD, US
Matthew G. Clark - Middletown MD, US
Scott Willens - White Marsh MD, US

Assignee:

U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND - Frederick MD

International Classification:

G01N 21/78
B01L 3/00

US Classification:

436 72, 436109, 436134, 436 98, 436119, 436103, 436106, 436124, 422430

Abstract:

The invention relates to methods and compositions for the rapid detection of small ligands, such as cyanide, carbon monoxide or azide, in small quantities. Specifically, metmyoglobin is used to bind small ligands which yield a product with a characteristic absorbance spectrum that is detectable and quantifiable. Also disclosed is a kit for detecting small ligands with metmyoglobin, which is portable and provides for practice of the invention without the use of harsh solvents or chemical reagents.

US Patent:

D3447987, Mar 1, 1994

Filed:

Jun 8, 1992

Appl. No.:

7/895385

Inventors:

Steven I. Baskin - Bel Air MD

US Classification:

D24134

US Patent:

52923070, Mar 8, 1994

Filed:

Sep 16, 1992

Appl. No.:

7/945671

Inventors:

Theodore W. Dolzine - Havre de Grace MD
Steven I. Baskin - Bel Air MD

International Classification:

A6MN 3100

US Classification:

604 54

Abstract:

A unit dosage, packaged for direct administration into a body cavity, is encapsulated in a packet between a pair of leaves of foil. The leaves are sealed to each other about their peripheries. The packet is packaged with a tubular injector having a longitudinal bore extending from the head end of the injector to the tail end. The packet is positioned in the bore adjacent the head end by a annular support member having a central opening in registry with the bore. A plunger is mounted in the bore and has a head adapted to slide in the bore and a tail projecting out of the tail end of the tubular injector, and the tail end of the plunger is used to displace the head of the plunger through the packet, through the opening in the annular support, and beyond the head end of the tubular injector. The head of the plunger is provided with a beveled surface along one side.