Steven A Cohen

US Patent:

6931440, Aug 16, 2005

Filed:

Apr 21, 1999

Appl. No.:

09/295718

Inventors:

Steven M Blumenau - Holliston MA, US
Steven Cohen - Westboro MA, US

Assignee:

EMC Corporation - Hopkinton MA

International Classification:

G06F015/16

US Classification:

709220, 709221, 709225, 709227, 709229

Abstract:

One embodiment is directed to a method and apparatus for modifying a configuration of a computer system including a host computer and at least one computer system resource accessible to at least one application program executing on the host computer. The computer system is dynamically reconfigured, without reinitializing the host computer or the application program, to alter a manner in which the at least one application program accesses the at least one computer system resource. Another embodiment is directed to a method and apparatus for responding to changes in a configuration of the computer system impacting a manner in which the at least one computer system resource is accessed by the host computer. Information relating to a first configuration of the computer system at a first point in time is stored, the first configuration relating to a first manner of accessing the at least one computer system resource by the host computer. A second configuration of the computer system at a second point in time is determined, the second configuration relating to a second manner of accessing the at least one computer system resource by the host computer.

US Patent:

7519696, Apr 14, 2009

Filed:

Jun 2, 2004

Appl. No.:

10/858597

Inventors:

Steven Blumenau - Holliston MA, US
Steven Cohen - Westboro MA, US

Assignee:

EMC Corporation - Hopkinton MA

International Classification:

G06F 15/177

US Classification:

709221, 709220, 709222, 712220, 710 2, 710 4, 710 5, 710 30, 711 4, 711 5, 711 40, 711100

Abstract:

One embodiment is directed to a method and apparatus for modifying a configuration of a computer system including a host computer and at least one computer system resource accessible to at least one application program executing on the host computer. The computer system is dynamically reconfigured, without reinitializing the host computer or the application program, to alter a manner in which the at least one application program accesses the at least one computer system resource. Another embodiment is directed to a method and apparatus for responding to changes in a configuration of the computer system impacting a manner in which the at least one computer system resource is accessed by the host computer. Information relating to a first configuration of the computer system at a first point in time is stored, the first configuration relating to a first manner of accessing the at least one computer system resource by the host computer. A second configuration of the computer system at a second point in time is determined, the second configuration relating to a second manner of accessing the at least one computer system resource by the host computer.

US Patent:

20010011348, Aug 2, 2001

Filed:

Mar 20, 2001

Appl. No.:

09/812743

Inventors:

Steven Blumenau - Holliston MA, US
Steven Cohen - Westboro MA, US
John Madden - Holden MA, US

International Classification:

G06F015/177

US Classification:

713/100000, 713/001000

Abstract:

Method and apparatus for detecting changes in a configuration of a computer system including a host computer and at least one computer system resource. Information relating to a reference configuration of the computer system is stored at a first point in time. A current configuration of the computer system is determined at a second point in time. The current configuration of the computer system is compared with the reference configuration to determine whether the current configuration differs from the reference configuration. An indication is provided when the current configuration of the computer system differs from the reference configuration.

US Patent:

20100168457, Jul 1, 2010

Filed:

Nov 6, 2007

Appl. No.:

12/447477

Inventors:

Moon Chul Jung - Marlborough MA, US
Edouard S. P. Bouvier - Stow MA, US
Steven A. Cohen - Hopkinton MA, US
Hua Yang - Franklin MA, US

Assignee:

WATERS TECHNOLOGIES CORPORATION - Milford MA

International Classification:

C07F 7/21

US Classification:

556425

Abstract:

High-pressure electrokinetic (“EK”) pumps comprising a hybrid monolith provide a high surface charge density and a continuous stable skeleton morphology with micrometer- sized through-pores. The hybrid monolith of the subject invention has superior mechanical strength and better stability in comparison to prior art monoliths with equivalent mechanical stability. The surface charge of the hybrid monolith can be modified and/or made stable by the use of different chemical reagents. The chemical reagents and resulting modification to the monolith serves to expand the usefulness of the hybrid monolith to a variety of pumping applications including chip-based systems and other applications where the ability to pump an acidic solution is required.

US Patent:

6240511, May 29, 2001

Filed:

Dec 14, 1998

Appl. No.:

9/211131

Inventors:

Steven M. Blumenau - Holliston MA
Steven Cohen - Westboro MA
John F. Madden - Holden MA

Assignee:

EMC Corporation - Hopkinton MA

International Classification:

G06F 944

US Classification:

713 1

Abstract:

Method and apparatus for detecting changes in a configuration of a computer system including a host computer and at least one computer system resource. Information relating to a reference configuration of the computer system is stored at a first point in time. A current configuration of the computer system is determined at a second point in time. The current configuration of the computer system is compared with the reference configuration to determine whether the current configuration differs from the reference configuration. An indication is provided when the current configuration of the computer system differs from the reference configuration.

US Patent:

52965996, Mar 22, 1994

Filed:

Sep 19, 1991

Appl. No.:

7/762579

Inventors:

Steven A. Cohen - Hopkinton MA
Dennis P. Michaud - Dracut MA

Assignee:

Millipore Corporation - Bedford MA

International Classification:

C07D23720
C07D21538
C07D21726

US Classification:

544235

Abstract:

A class of novel heterocyclic aromatic carbamate compounds is described. A method of derivatizing amine-functional compounds with the novel carbamates is also disclosed. The derivatives can be detected using a fluorescence detector. The present composition and method allow femtomole quantities of amine compounds to be detected and measured.

US Patent:

20190194315, Jun 27, 2019

Filed:

Jun 17, 2016

Appl. No.:

15/737042

Inventors:

Tinya ABRAMS - Acton MA, US
Steven Bruce COHEN - San Diego CA, US
Joseph Anthony D'Alessio - Boston MA, US
Jason Damiano - Oakland CA, US
Clemens Durr - Weil am Rhein, DE
Bernhard Hubert GEIERSTANGER - Solana Beach CA, US
Thomas HUBER - Basel, CH
Hidetomo IMASE - Somerville MA, US
Yunho JIN - San Diego CA, US
Daniel MENEZES - Berkeley CA, US
Kathy MILLER - San Francisco CA, US
Morvarid MOHSENI - Boston MA, US
Weijia OU - San Diego CA, US
Katherine RENDAHL - Berkeley CA, US
Tetsuo UNO - San Diego CA, US
Yongqin WAN - San Diego CA, US
Xing WANG - San Diego CA, US

Assignee:

Novartis AG - Basel

International Classification:

C07K 16/28
A61K 47/65
A61K 47/68
A61P 35/00
A61K 38/07

Abstract:

This application discloses anti-P-cadherin antibodies, antigen binding fragments thereof, and antibody drug conjugates of said antibodies or antigen binding fragments, particularly antibody drug conjugates comprising anti-P-cadherin antibodies conjugated to auristatin analogs. The invention also relates to methods of treating cancer using the antibody drug conjugates. Also disclosed herein are methods of making the antibodies, antigen binding fragments, and antibody drug conjugates, and methods of using the antibodies and antigen binding fragments as diagnostic reagents.

US Patent:

20170035905, Feb 9, 2017

Filed:

Oct 3, 2016

Appl. No.:

15/284444

Inventors:

Tinya Abrams - Acton MA, US
Steven Bruce Cohen - San Diego CA, US
Christie P. Fanton - Oakland CA, US
Thomas Huber - Basel, CH
Kathy Miller - San Francisco CA, US
Siew Ho Schleyer - El Cerrito CA, US
Kathrin Ulrike Tissot-Daguette - Neuried, DE
Catrin Finner - Taxetweg, DE

Assignee:

Novartis AG - Basel

International Classification:

A61K 47/48
A61K 47/26
A61K 9/19
A61K 47/12
C07K 16/32
A61K 31/537

Abstract:

The present invention relates to anti-cKIT antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.