CHEN Haibin - SG, SG Steven J. Collier - Lexington MA, US Jovana NAZOR - Santa Clara, US Joly SUKUMARAN - SG, SG Derek SMITH - Singapore, SG Jeffrey C. MOORE - Westfield NJ, US Gregory HUGHES - Scotch Plains NJ, US Jacob JANEY - New York NY, US Gjalt HUISMAN - San Carlos CA, US Scott NOVICK - Palo Alto CA, US Nicholas AGARD - San Francisco CA, US Oscar ALVIZO - Freemont CA, US Gregory COPE - Menlo Park CA, US Wan Lin YEO - Singapore, SG Stephanie NG - Redwood City CA, US
The present disclosure provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the engineered imine reductases, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.
Engineered Imine Reductases And Methods For The Reductive Amination Of Ketone And Amine Compounds
- Redwood City CA, US Steven J. Collier - Concord MA, US Jovana Nazor - Milpitas CA, US Joly Sukumaran - Singapore, SG Derek Smith - Singapore, SG Jeffrey C. Moore - Westfield NJ, US Gregory Hughes - Scotch Plains NJ, US Jacob Janey - New York NY, US Gjalt W. Huisman - Redwood City CA, US Scott J. Novick - Palo Alto CA, US Nicholas J. Agard - San Francisco CA, US Oscar Alvizo - Fremont CA, US Gregory A. Cope - Menlo Park CA, US Wan Lin Yeo - Singapore, SG Stefanie Ng Minor - Redwood City CA, US
The present disclosure provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the engineered imine reductases, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.
Ketoreductase Polypeptides For The Preparation Of Phenylephrine
- Redwood City CA, US Steven J. Collier - Concord MA, US Hans-Georg Joerg Hennemann - Bedburg, DE Seong Ho Oh - Singapore, SG Wenjuan Zha - Singapore, SG
International Classification:
C12N 9/04 A61K 31/137 C12P 13/00
Abstract:
The disclosure relates to engineered ketoreductase polypeptides and processes of using the polypeptides for production of phenylephrine.
Biocatalysts And Methods For Synthesizing Derivatives Of Tryptamine And Tryptamine Analogs
- Redwood City CA, US Derek J. Smith - Singapore, SG Michael A. Crowe - Singapore, SG Shiwei Song - Singapore, SG Steven J. Collier - Concord MA, US
International Classification:
C12N 9/10 C12P 17/10
Abstract:
The present disclosure provides engineered transaminase polypeptides for the production of amines, polynucleotides encoding the engineered transaminases, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases to prepare compounds useful in the production of active pharmaceutical agents.
- Redwood City CA, US Steven J. Collier - Concord MA, US Joly Sukumaran - Singapore, SG Wan Lin Yeo - Singapore, SG Oscar Alvizo - Fremont CA, US Ee Ling Teo - Mauchline East Ayrshire, GB Robert J. Wilson - San Francisco CA, US Junye Xu - Singapore, SG
The present disclosure provides engineered transaminase polypeptides for the production of amines, polynucleotides encoding the engineered transaminases, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases to prepare compounds useful in the production of active pharmaceutical agents.
Biocatalysts For The Preparation Of Hydroxy Substituted Carbamates
- Redwood City CA, US Haibin Chen - Beijing, CN Anupam Gohel - Bekasi, ID Steven J. Collier - Concord MA, US Derek J. Smith - Singapore, SG Birgit Kosjek - Westfield NJ, US Jacob Janey - New York NY, US
International Classification:
C12N 9/04 C12P 41/00 C12P 13/00 C12P 13/02
Abstract:
The present disclosure relates to engineered ketoreductase polypeptides for the preparation of hydroxyl substituted carbamate compounds, and polynucleotides, vectors, host cells, and methods of making and using the ketoreductase polypeptides.
Ketoreductase Polypeptides For The Preparation Of Phenylephrine
- Redwood City CA, US Steven J. Collier - Concord MA, US Hans-Georg Joerg Hennemann - Bedburg, DE Seong Ho Oh - Singapore, SG Wenjuan Zha - Singapore, SG
International Classification:
C12N 9/04 A61K 31/137 C12P 13/00
Abstract:
The disclosure relates to engineered ketoreductase polypeptides and processes of using the polypeptides for production of phenylephrine.
Name / Title
Company / Classification
Phones & Addresses
Mr. Steven P. Collier Partner
Connelly, Jackson & Collier, LLP Attorneys & Lawyers. Attorneys (Also See Lawyers)
405 Madison Avenue, Suite 2300, Toledo, OH 43604 4192432100, 4192437119
White River Rural HealthArcare 400 Hwy 64 E, Augusta, AR 72006 8703472508 (phone), 8703475556 (fax)
Education:
Medical School University of Arkansas College of Medicine at Little Rock Graduated: 1980
Languages:
English Spanish
Description:
Dr. Collier graduated from the University of Arkansas College of Medicine at Little Rock in 1980. He works in Augusta, AR and specializes in Family Medicine. Dr. Collier is affiliated with North East Arkansas Baptist Memorial Hospital.
Austin, TXVP Business Development at Milsoft Utility Solutio... Past: VP Competitive Intelligence at National Rural Telecommunications Cooperative, President &... Born in Alamogordo, NM.
Grew up in Carlsbad, NM.
One sister, Denise, married to Dan Williams, living in Corona, NM.
6'4" tall. 190 lbs.
Married to Allison... Born in Alamogordo, NM.
Grew up in Carlsbad, NM.
One sister, Denise, married to Dan Williams, living in Corona, NM.
6'4" tall. 190 lbs.
Married to Allison Leigh Conley.
SEVEN CHILDREN! Rachel, Joel, Lori, Ginna, Zoe, twins Harper & Raine
One son-in-law, Mike Wheeler & two granddaughters, Victoria...
Bainbridge-Guilford High School Bainbridge NY 1989-1993
Community:
Bridget Winn, David Louden, Jessica Wright, Kristie Dietrich, Lisa Wayman, Christi Turtur, Scott Leach, Jessica Birdsall, Jennifer Hartwell, Robin Rusweiler, Franklin Devries