Steven Michael Cramer

US Patent:

6573373, Jun 3, 2003

Filed:

Jun 29, 1999

Appl. No.:

09/343006

Inventors:

Abhinav A. Shukla - Bothell WA
Ranjit R. Deshmukh - San Diego CA
Steven M. Cramer - Schenectady NY
James A. Moore - Troy NY

Assignee:

ISIS Pharmaceuticals, Inc. - Carlsbad CA
Rensselaer Polytechin Institute - Troy NY

International Classification:

C07H 2100

US Classification:

536 254, 536 2541

Abstract:

A method for purifying oligonucleotides by displacement chromatography on anion-exchange media, using high affinity, low molecular weight (less than about 10000 Da) displacers, is disclosed. Several examples of high affinity, low molecular weight anionic displacers are provided, including polycyclic aromatic compounds having sulfonic acid moieties attached thereon. The efficacy of the technique for high resolution separation of oligonucleotides is demonstrated for an industrial mixture.

US Patent:

6828436, Dec 7, 2004

Filed:

May 15, 2002

Appl. No.:

10/146266

Inventors:

Abhinav A. Shukla - Bothell WA
Ranjit R. Deshmukh - San Diego CA
Steven M. Cramer - Schenectady NY
James A. Moore - Troy NY

Assignee:

ISIS Pharmaceuticals, Inc. - Carlsbad CA
Rensselaer Polytechnic Institute - Troy NY

International Classification:

C07H 2100

US Classification:

536 254, 536 2541, 536 553, 530416, 530412, 530344

Abstract:

A method for purifying oligonucleotides by displacement chromatography on anion-exchange media, using high affinity, low molecular weight (less than about 10000 Da) displacers, is disclosed. Several examples of high affinity, low molecular weight anionic displacers are provided, including polycyclic aromatic compounds having sulfonic acid moieties attached thereon. The efficacy of the technique for high resolution separation of oligonucleotides is demonstrated for an industrial mixture.

US Patent:

20190319660, Oct 17, 2019

Filed:

Oct 5, 2018

Appl. No.:

16/152846

Inventors:

- Fort Worth TX, US
Steven Cramer - Redmond WA, US

International Classification:

H04B 1/3888
F21V 29/70
G03B 17/56
H01L 27/15
H01L 33/54
H01L 33/64
F21V 33/00
F21L 4/00
F21V 29/507
H04M 1/18
H04M 1/22

Abstract:

A lighting device is disclosed having a plurality of LED chips mounted on a single planar flexible substrate, wherein the single planar flexible substrate is disposed in an arcuate orientation. A heat sink having an arcuate surface shaped to approximate the arcuate orientation of the flexible substrate is coupled to the flexible substrate between complementary arcuate surfaces. A luminescent coating is disposed about a top surface of the arcuate single planar flexible substrate.

US Patent:

20180058671, Mar 1, 2018

Filed:

Aug 24, 2016

Appl. No.:

15/245330

Inventors:

- Grand Prairie TX, US
Steven Cramer - Redmond WA, US

International Classification:

F21V 21/096
F21V 17/10
F21L 4/02
F21V 23/04
F21V 3/00

Abstract:

A lighting device includes a primary housing having a light source and a secondary housing having a light source. The primary housing and the secondary housing can be magnetically and releasably coupled to each other by at least one magnet on either or both housings. The primary housing can include an upper shell and a lower shell pivotally coupled to each other to form a clamshell configuration. A hands-free emergency lighting method can include decoupling the primary housing from the secondary housing and magnetically coupling the secondary housing to a metal surface, such as a vehicle, to indicate an emergency while the primary housing can be opened and used to illuminate an area.

US Patent:

20170134065, May 11, 2017

Filed:

Oct 6, 2016

Appl. No.:

15/287225

Inventors:

- Grand Prairie TX, US
Steven Cramer - Redmond WA, US

International Classification:

H04B 1/3888

Abstract:

A protective covering configured for use with a mobile electronics device, including a front wall and a plurality of side walls defining a primary cavity. A back wall is disposed within the primary cavity separating the primary cavity into a protective covering electronics housing cavity and a mobile electronic device housing cavity. One or more apertures are disposed within the front wall. A light source is disposed within the protective covering electronics housing cavity, wherein at least a portion of the light source is disposed outside of the protective covering electronics housing cavity and through at least one of the one or more apertures in the front wall. A heat sink is disposed within the protective covering electronics housing cavity and in contact with the light source.

US Patent:

20160351619, Dec 1, 2016

Filed:

Apr 25, 2016

Appl. No.:

15/138027

Inventors:

- Grand Prairie TX, US
Steven Cramer - Redmond WA, US

International Classification:

H01L 27/15
H01L 33/54
H01L 33/64

Abstract:

A lighting device is disclosed having a plurality of LED chips mounted on a single planar flexible substrate, wherein the single planar flexible substrate is disposed in an arcuate orientation. A heat sink having an arcuate surface shaped to approximate the arcuate orientation of the flexible substrate is coupled to the flexible substrate between complementary arcuate surfaces. A luminescent coating is disposed about a top surface of the arcuate single planar flexible substrate.

US Patent:

20160315650, Oct 27, 2016

Filed:

Oct 9, 2015

Appl. No.:

14/880071

Inventors:

- Grand Prairie TX, US
Steven Cramer - Redmond WA, US

International Classification:

H04B 1/3888
F21V 33/00
F21V 23/02
F21S 4/22
F21V 29/503
F21V 23/04
F21V 29/87
H04M 1/02
F21V 29/70

Abstract:

A protective covering configured for use with a mobile electronics device, including a front wall and a plurality of side walls defining a primary cavity. A back wall is disposed within the primary cavity separating the primary cavity into a protective covering electronics housing cavity and a mobile electronic device housing cavity. One or more apertures are disposed within the front wall. A light source is disposed within the protective covering electronics housing cavity, wherein at least a portion of the light source is disposed outside of the protective covering electronics housing cavity and through at least one of the one or more apertures in the front wall. A heat sink is disposed within the protective covering electronics housing cavity and in contact with the light source.

US Patent:

20140162729, Jun 12, 2014

Filed:

Dec 9, 2013

Appl. No.:

14/101007

Inventors:

- Woodinville WA, US
Steven M. Cramer - Redmond WA, US

Assignee:

Bensussen Deutsch & Associates, Inc - Woodinville WA

International Classification:

H04M 1/02
H04B 1/38

US Classification:

455566

Abstract:

An accessory for processor-based mobile devices is selectively securely attachable to the mobile device and at least partially wraps around at least one edge of the mobile device, so that a photo-reflective dipolar electronic display incorporated into the outer shell of the accessory can provide a visual platform for sustained image retention with negligible power consumption. Content (e.g., image data) is transmitted wirelessly from the mobile device to the accessory. Electronic and/or electrical components for receiving, directing, decrypting, and displaying images can be incorporated into a resilient sleeve, integrated into a hard shell case, or a combination of the two. Content can originate in the mobile device, or at a remote content server, to periodically update an image on the accessory.