Dr. Cullen graduated from the Northwestern University Feinberg School of Medicine in 1992. He works in San Clemente, CA and specializes in Internal Medicine. Dr. Cullen is affiliated with Mission Hospital.
Summit Pathology 1400 E Boulder St, Colorado Springs, CO 80909 7193655808 (phone), 7193656908 (fax)
Education:
Medical School University of Colorado School of Medicine at Denver Graduated: 1981
Languages:
English
Description:
Dr. Cullen graduated from the University of Colorado School of Medicine at Denver in 1981. He works in Colorado Springs, CO and specializes in Anatomic Pathology & Clinical Pathology. Dr. Cullen is affiliated with Memorial Hospital Central.
Skin Pros 1287 N Main St, Providence, RI 02904 4012722724 (phone), 4012722784 (fax)
Languages:
English Portuguese
Description:
Mr. Cullen works in Providence, RI and 1 other location and specializes in Dermatology. Mr. Cullen is affiliated with Rhode Island Hospital, Roger Williams Medical Center and The Miriam Hospital.
Yu-Ming Pu - Gurnee IL, US Alan Christesen - Round Lake IL, US Steven Cullen - Lake Villa IL, US Yi-Yin Ku - Buffalo Grove IL, US
Assignee:
ABBOTT LABORATORIES - Abbott Park IL
International Classification:
C07D 513/04
US Classification:
546114
Abstract:
A process for the preparation of compounds of formula (I) or a salt thereofwherein X, X, X, X, R, u, R, R, z, and Aare as defined in the specification is disclosed.
Macrocyclic Hepatitis C Serine Protease Inhibitors
Hui-Ju Chen - Grayslake IL, US Keith F. McDaniel - Wauconda IL, US Brian E. Green - Wonder Lake IL, US Jason P. Shanley - Chicago IL, US Albert W. Kruger - Pleasant Prairie WI, US Jorge Gandarilla - North Riverside IL, US Dennie S. Welch - Lake Bluff IL, US Russell D. Cink - Grayslake IL, US Steven C. Cullen - Lake Villa IL, US Yonghua Gai - North Grafton MA, US Guoqiang Wang - Belmont MA, US Yat Sun Or - Watertown MA, US
Assignee:
ENANTA PHARMACEUTICALS, INC. - Watertown MA ABBOTT LABORATORIES - Abbott Park IL
International Classification:
A61K 38/12 A61P 31/12 C07K 5/087
US Classification:
514 37, 530331, 514 211
Abstract:
The present invention relates to novel macrocyclic compounds and methods of treating a hepatitis C infection in a subject in need of such therapy with said macrocyclic compounds. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient.
Azaadamantane Formate Ester And Process For Preparing Azaadamantane Derivatives
- North Chicago IL, US Shuang CHEN - Gurnee IL, US Steven Cramer CULLEN - Lake Villa IL, US James Joseph NAPIER - Antioch IL, US
International Classification:
C07D 471/18 C07D 285/12 C07D 285/135
Abstract:
A compound, (4s)-1-azaadamantane-4yl formate ester, is described. In addition, a process is described for preparing (4s)-1-azaadamantane-4yl formate ester, aminothiadiazole-phenyl phosphate salt, bromothiadizole-phenyl or (4s)-4-(5-phenyl-1,3,4-thiadiazol-2-yloxy)-1-azatricyclo[3.3.1.1]-decane dihydrogen citrate. Furthermore, a process is described, comprising step of hydrolyzing (4s)-1-azaadamantane-4yl formate ester to form (4s)-1-azaadamantan-4-ol HBr salt.
Macrocyclic Hepatitis C Serine Protease Inhibitors
- Watertown MA, US - North Chicago IL, US Brian E. Green - Wonder Lake IL, US Jason P. Shanley - Chicago IL, US Albert W. Kruger - Pleasant Prairie WI, US Jorge Gandarilla - North Riverside IL, US Dennie S. Welch - Lake Bluff IL, US Russell D. Cink - Grayslake IL, US Steven C. Cullen - Lake Villa IL, US Yonghua Gai - North Grafton MA, US Guoqiang Wang - Belmont MA, US Yat Sun Or - Watertown MA, US
International Classification:
C07K 5/083
US Classification:
514 43, 530331
Abstract:
The present invention relates to novel macrocyclic compounds and methods of treating a hepatitis C infection in a subject in need of such therapy with said macrocyclic compounds. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient.
Azaadamantane Formate Ester And Process For Preparing Azaadamantane Derivatives
- North Chicago IL, US Shuang CHEN - Gurnee IL, US Steven Cramer CULLEN - Lake Villa IL, US James Joseph NAPIER - Antioch IL, US
Assignee:
AbbVie Inc. - North Chicago IL
International Classification:
C07D 471/18 C07D 285/135 C07D 285/12 C07C 249/02
US Classification:
546 74, 564271, 548138, 548136
Abstract:
A compound, (4s)-1-azaadamantane-4yl formate ester, is described. In addition, a process is described for preparing (4s)-1-azaadamantane-4yl formate ester, aminothiadiazole-phenyl phosphate salt, bromothiadizole-phenyl or (4s)-4-(5-phenyl-1,3,4-thiadiazol-2-yloxy)-1-azatricyclo[3.3.1.1]-decane dihydrogen citrate. Furthermore, a process is described, comprising step of hydrolyzing (4s)-1-azaadamantane-4yl formate ester to form (4s)-1-azaadamantan-4-ol HBr salt.