- Cambridge MA, US Steven James DeMarco - Boxford MA, US Sylvia Tobe - Winchester MA, US Michelle Denise Hoarty - Billerica MA, US Robert Paul Hammer - Maynard MA, US Douglas A. Treco - Arlington MA, US Kathleen Seyb - Wakefield MA, US Vaishnavi Rajagopal - Andover MA, US Guo-Qing Tang - Acton MA, US Douangsone D. Vadysirisack - Boston MA, US Ramin Farzaneh-Far - Brookline MA, US
International Classification:
A61K 38/12 A61K 9/00 A61K 39/395 A61P 7/06
Abstract:
The present disclosure relates to polypeptide modulators of complement activity, including cyclic polypeptide modulators. Included are methods of utilizing such modulators as therapeutics. Also provided are methods of measuring C5 and related complexes using C5 binding agents.