Steven L Harvey

US Patent:

7229819, Jun 12, 2007

Filed:

Oct 27, 2003

Appl. No.:

10/694206

Inventors:

Tu-Chen Cheng - Timonium MD, US
Joseph J. DeFrank - Bel Air MD, US
Steven P. Harvey - Fallston MD, US
Vipin K. Rastogi - Bel Air MD, US

Assignee:

The United States of America as represented by the Secretary of the Army - Washington DC

International Classification:

A62D 3/00
C02F 3/34
D06M 16/00

US Classification:

435264, 435262, 4352625

Abstract:

The present invention relates to a near-universal non-corrosive, non-toxic, environmentally safe and user friendly decontaminant capable of detoxifying organophosphorus (OP)-based G-type, V-type neurotoxic chemical warfare, sulfur-mustard, and related OP based hazardous industrial materials in a dry powder form. The decontaminant contains OPH enzyme, OPAA enzyme, DFPase enzyme, dehalogenase enzyme, quaternary ammonium salt, a pH control reagent, a fire-fighting agent, and a foaming agent. The decontaminant is mixed with available water for use.

US Patent:

7723558, May 25, 2010

Filed:

Jun 5, 2007

Appl. No.:

11/758431

Inventors:

Tu-Chen Cheng - Timonium MD, US
Joseph J. DeFrank - Bel Air MD, US
Steven P. Harvey - Fallston MD, US
Vipin K. Rastogi - Bel Air MD, US

Assignee:

The United States of America as represented by the Secretary of the Army - Washington DC

International Classification:

A62D 3/34

US Classification:

588408, 588316, 588405

Abstract:

The present invention relates to a near-universal non-corrosive, non-toxic, environmentally safe and user friendly decontaminant capable of detoxifying organophosphorus (OP)-based G-type, V-type neurotoxic chemical warfare, sulfur-mustard, and related OP based hazardous industrial materials in a dry powder form. The decontaminant contains OPH enzyme, OPAA enzyme, DFPase enzyme, dehalogenase enzyme, quaternary ammonium salt, a pH control reagent, a fire-fighting agent, and a foaming agent. The decontaminant is mixed with available water for use.

US Patent:

8357335, Jan 22, 2013

Filed:

Nov 9, 2005

Appl. No.:

11/272422

Inventors:

Steven P. Harvey - Fallston MD, US
Joseph J. DeFrank - Bel Air MD, US

Assignee:

The United States of America as Represented by the Secretary of the Army - Washington DC

International Classification:

G01N 33/00

US Classification:

422401, 422 50, 422561, 436104, 436165, 4352625, 588405

Abstract:

An assay for screening potential hydrolysis enhancing agents capable of facilitating the hydrolysis of a substantially water insoluble halogenated compound such as mustard gas (HD) in an aqueous reaction mixture is disclosed. The assay includes at least one chamber adapted for receiving and retaining the substantially water insoluble mustard gas compound and a potential hydrolysis agent in an aqueous reaction mixture, and a pH indicating agent adapted to produce a visible color change corresponding to the amount of the substantially water insoluble mustard gas compound hydrolyzed in the aqueous reaction mixture wherein the rate of hydrolysis can be established by measuring the change in the detectable signal over time.

US Patent:

60177500, Jan 25, 2000

Filed:

Nov 12, 1998

Appl. No.:

9/197538

Inventors:

Steven P. Harvey - Fallston MD
Linda L. Szafraniec - Bel Air MD
William T. Beaudry - Bel Air MD

Assignee:

The United States of America as represented by the Secretary of the Army - Washington DC

International Classification:

B09B 300

US Classification:

4352625

Abstract:

A process for the detoxification or demilitarization of the chemical warf agent HT, a mixture of 2,2'-dichlorodiethyl sulfide and bis-(2-(2-chloroethylthio)ethyl) ether, is disclosed. The process includes 1) treating HT with a hydrolyzing agent to form a mixture of thiodiglycol (TDG) and bis-(2-(2-hydroxyethylthio)ethyl) ether(s?) (T-OH); 2) neutralizing the TDG and T-OH mixture to a pH sufficient for biodegradation of the mixture; and biodegrading the neutralized TDG and T-OH mixture. In preferred embodiments, the hydrolyzing agent is water and the neutralizing is carried out with NAOH. Biodegradation is preferably carried out with a sequential batch reactor.