The present disclosure relates to compounds of formula (I-A) using the compoundswherein Ring A and the variables X, Y, R, R, R, R, R, R, R, and m are defined herein, to pharmaceutical compositions comprising the compounds, and methods of using the compounds.
- Cambridge MA, US Thomas G. Gant - Carlsbad CA, US Steven P. Langston - North Andover MA, US Edward J. Olhava - Newton MA, US Stephane Peluso - Somerville MA, US
International Classification:
C07H 19/16 C07H 19/14 C07D 487/04 C07D 473/34
Abstract:
This invention relates to compounds that inhibit E1 activating enzymes, pharmaceutical compositions comprising the compounds, and methods of using the compounds. The compounds are useful for treating disorders, particularly cell proliferation disorders, including cancers, inflammatory and neurodegenerative disorders; and inflammation associated with infection and cachexia.
REO / Bank Owned Short sales Residential sales First time home buyers
Work:
8772861833 (Phone) License #BRE #01781940
Client type:
Home Buyers Home Sellers
Property type:
Single Family Home Condo/Townhome Residential Rental
About:
Here is where I can write a beautiful story about my past experiences and how great I am and why you should use me and only me. But there is a reality and here it is. When your looking to buy or sell your home you have a lot of choices to make, only one of which is who will you be working with? Who will be your Realtor? Realtors in many ways are facilitators. We bring our knowledge and experience to help you, protect you, and to give you guidance during the process. In the end as a Realtor we provide you with an experience. The experience of purchasing or selling your home. Realtors can help make that process pleasant and a dream come true or add frustration making it dark and troublesome. This is your journey, your experience and I will strive to make it wonderful one. I understand you have a choice in who accompanies you on your buying and/or selling journey. I hope you will hire me for the job.
Pleasanton, CAFormally I was working at Windermere Welcome Home as a Realtor and Consultant in Pleasanton, the broker changed the franchise branding to Prudential so poof I... Formally I was working at Windermere Welcome Home as a Realtor and Consultant in Pleasanton, the broker changed the franchise branding to Prudential so poof I am now with Prudential California Realty.
I am located in Pleasanton advising clients about Real Estate in Pleasanton, Dublin and Livermore...