Steven Chingyao Lin

US Patent:

6383764, May 7, 2002

Filed:

Apr 28, 2000

Appl. No.:

09/560915

Inventors:

Olivier Civelli - Irvine CA
Steven Lin - Upland CA

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

G01N 3353

US Classification:

435 78, 435 72, 514 2, 436501

Abstract:

The invention provides a substantially pure Prolactin Releasing Peptide (PrRP) functional analog which suppresses absence seizures in a mammal, and related pharmaceutical compositions. The invention also provides a method of controlling absence seizures in a mammal, by administering to a mammal susceptible to absence seizures an effective amount of PrRP or a PrRP functional analog. Also provided are methods of identifying a compound that modulates AMPA receptor signaling in a mammal, by providing a compound that is a PrRP or PrRP functional analog, and determining the ability of the compound to modulate AMPA receptor signaling. The invention also provides methods of identifying a compound for controlling absence seizures in a mammal, by providing a compound that is a PrRP or PrRP functional analog, and determining the ability of the compound to control absence seizures in a mammal. Also provided are pharmaceutical compositions for controlling absence seizures in a mammal. The compositions and related methods contain a compound identified by the methods of the invention as a compound that modulates AMPA receptor signaling or as a compound that controls absence seizures.

US Patent:

6884596, Apr 26, 2005

Filed:

Aug 17, 2001

Appl. No.:

09/932161

Inventors:

Olivier Civelli - Irvine CA, US
Steven Lin - Upland CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

G01N033/53
G01N033/566
G01N033/567
A61K038/00

US Classification:

435 78, 435 72, 514 2, 436501, 436503

Abstract:

The invention provides methods of screening for a compound for promoting wakefulness in a mammal. The method is practiced by providing a compound that is a PrRP receptor agonist and determining the ability of the compound to promote wakefulness. Also provided by the invention are methods of screening for a compound for promoting sleep in a mammal. The methods are practiced by providing a compound that is a PrRP receptor antagonist and determining the ability of the compound to promote sleep. In addition, the invention provides a method of promoting wakefulness in a mammal. The method is practiced by administering to a mammal an effective amount of a PrRP receptor agonist. The invention further provides a method of promoting sleep in a mammal. The method is practiced by administering to a mammal an effective amount of a PrRP receptor antagonist.

US Patent:

7675862, Mar 9, 2010

Filed:

Aug 17, 2006

Appl. No.:

11/506351

Inventors:

Anthony Pham - S. San Gabriel CA, US
Steven Lin - Cerritos CA, US
Jonathan Bettino - Huntington Beach CA, US
David Hoard - Escondido CA, US

Assignee:

Belkin International, Inc. - Compton CA

International Classification:

H04L 12/26

US Classification:

370241, 370245

Abstract:

In one embodiment, a networking hardware element () capable of coupling computer network elements () comprises a network diagnostic mechanism () that is capable of mapping the computer network elements and that is also capable of determining a connection status for the computer network elements. The networking hardware element also comprises a display () that is capable of communicating with the network diagnostic mechanism and that is also capable of displaying a network layout map () of representations of the computer network elements and the connection status of the computer network elements.

US Patent:

20030171270, Sep 11, 2003

Filed:

Mar 12, 2002

Appl. No.:

10/096777

Inventors:

Olivier Civelli - Irvine CA, US
Steven Lin - Upland CA, US

Assignee:

Regents of the University of California

International Classification:

A61K038/22
A61K031/496
A61K031/19

US Classification:

514/012000, 530/399000, 514/255040, 514/557000

Abstract:

The invention provides a substantially pure Prolactin Releasing Peptide (PrRP) functional analog which suppresses absence seizures in a mammal, and related pharmaceutical compositions. The invention also provides a method of controlling absence seizures in a mammal, by administering to a mammal susceptible to absence seizures an effective amount of PrRP or a PrRP functional analog. Also provided are methods of identifying a compound that modulates AMPA receptor signaling in a mammal, by providing a compound that is a PrRP or PrRP functional analog, and determining the ability of the compound to modulate AMPA receptor signaling. The invention also provides methods of identifying a compound for controlling absence seizures in a mammal, by providing a compound that is a PrRP or PrRP functional analog, and determining the ability of the compound to control absence seizures in a mammal. Also provided are pharmaceutical compositions for controlling absence seizures in a mamma. The compositions and related methods contain a compound identified by the methods of the invention as a compound that modulates AMPA receptor signaling or as a compound that controls absence seizures.

US Patent:

20080046561, Feb 21, 2008

Filed:

Jan 5, 2007

Appl. No.:

11/650019

Inventors:

Anthony Pham - S. San Gabriel CA, US
Steven Lin - Cerritos CA, US
Jonathan Bettino - Huntington CA, US
David W. Hoard - Escondido CA, US
Robert W. Reay - Rochester NY, US

Assignee:

Belkin International, Inc. - Compton CA

International Classification:

G06F 15/173

US Classification:

709224

Abstract:

In one embodiment, a networking hardware element () capable of coupling together computer network elements () includes a network diagnostic mechanism () and a display (). The display is electrically coupled to the network diagnostic mechanism and is capable of displaying network information and additional information.

US Patent:

20100138519, Jun 3, 2010

Filed:

Feb 5, 2010

Appl. No.:

12/700915

Inventors:

Anthony Pham - San Gabriel CA, US
Steven Lin - Cerritos CA, US
Jonathan Bettino - Huntington Beach CA, US
David W. Hoard - Escondido CA, US

Assignee:

BELKIN INTERNATIONAL, INC. - Compton CA

International Classification:

G06F 15/173
G06F 15/177

US Classification:

709220, 709224

Abstract:

Examples of networking hardware with network layout maps thereon are disclosed herein. Other examples, embodiments, and related methods are also described herein.

US Patent:

D3726550, Aug 13, 1996

Filed:

Sep 26, 1994

Appl. No.:

D/028895

Inventors:

Steven Lin - Arcadia CA

Assignee:

Concord Manufacturing Systems - San Dimas CA

US Classification:

D 8102

US Patent:

52045218, Apr 20, 1993

Filed:

Mar 3, 1992

Appl. No.:

7/845283

Inventors:

Steven H. Lin - Temple City CA
Jae H. Kim - Bellevue WA
Demetri Psaltis - Pasadena CA

Assignee:

The United States of America as represented by the Administrator of the
National Aeronautics and Space Administration - Washington DC

International Classification:

H01J 3150

US Classification:

250214LS

Abstract:

An integrated, optoelectronic, variable thresholding neuron implemented monolithically in a GaAs integrated circuit and exhibiting high differential optical gain and low power consumption. Two alternative embodiments each comprise an LED monolithically integrated with a detector and two transistors. One of the transistors is responsive to a bias voltage applied to its gate for varying the threshold of the neuron. One embodiment is implemented as an LED monolithically integrated with a double heterojunction bipolar phototransistor (detector) and two metal semiconductor field-effect transistors (MESFET's) on a single GaAs substrate and another embodiment is implemented as an LED monolithically integrated with three MESFET's (one of which is an optical FET detector) on a single GaAs substrate. The first noted embodiment exhibits a differential optical gain of 6 and an optical switching energy of 10 pJ. The second embodiment has a differential optical gain of 80 and an optical switching energy or 38 pJ.