- Alachua FL, US Adrian M Timmers - Burlington MA, US Judith Newmark - Milford MA, US Steven Pennock - Leominster MA, US Chunjuan Song - Chestbrook PA, US Lisa Keyes - Apex NC, US
International Classification:
C12N 15/86 A61P 27/02
Abstract:
The present invention provides isolated promoters, transgene expression cassettes, vectors, kits, and methods for treatment of age-related macular generation and other genetic diseases that affect the cone cells of the retina.
Adeno-Associated Virus (Aav) Systems For Treatment Of Genetic Hearing Loss
- Alachua FL, US Luis David Jaramillo - Cambridge MA, US Adrian Timmers - Alachua FL, US Steven Pennock - Leominster MA, US Mark Shearman - Alachua FL, US
International Classification:
C12N 15/86 C12N 15/66 C07H 21/04
Abstract:
Described herein are optimally-modified GJB2 cDNA and associated genetic elements for use in recombinant adeno-associated virus (rAAV)-based gene therapy for the treatment of genetic hearing loss.
DEPARTMENT OF OPHTHALMOLOGY, HARVARD MEDICAL SCHOOL
2014 to 2000 INSTRUCTOR OF OPHTHALMOLOGYSCHEPENS EYE RESEARCH INSTITUTE / MASSACHUSETTS EYE
2013 to 2000 PRINCIPAL INVESTIGATORSCHEPENS EYE RESEARCH INSTITUTE / MASSACHUSETTS EYE Boston, MA 2008 to 2013 POST-DOCTORAL RESEARCH FELLOWPH.D. CELL BIOLOGY, UNIVERSITY OF ALBERTA Edmonton, AB 2001 to 2007 Supervisor
Education:
University of Alberta Edmonton, AB 2001 to 2007 Ph.D. in Cell BiologyUniversity of Alberta Edmonton, AB 1999 to 2000 Specialization Certificate in BiochemistryUniversity of Alberta Edmonton, AB 1996 to 1999 BSc in General Science
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Steven Pennock (1972-1973), Kathi Janne (1974-1978), Maralene Fry (1970-1974), Anna Haugen (1968-1972), Ashlee Novotny (1988-1992), David Ellenberger (1975-1979)