Steven J Potts

US Patent:

20170298434, Oct 19, 2017

Filed:

Jul 5, 2017

Appl. No.:

15/642249

Inventors:

- Westminster CO, US
Steven J. Potts - Anthem AZ, US

Assignee:

Flagship Biosciences, Inc. - Westminster CO

International Classification:

C12Q 1/68
G01N 33/569
G01N 33/569
G06K 9/00

Abstract:

The disclosure concerns a method for measuring and reporting vascularity in a biological tissue sample. The method generally includes: within a digital image of a tissue section, (i) identifying endothelial cells, lymphatic cells, or a combination thereof; (ii) mapping one or more proximity regions, each of the proximity regions defining an area between detected vessels and a first distance outwardly therefrom; and (iii) calculating one or more of: a vessel proximity score or a hypoxia score, wherein the vessel proximity score relates a composition of objects within the proximity regions, and wherein the hypoxia score relates a composition of tissue within or outside of the proximity regions, respectively.

US Patent:

20150004630, Jan 1, 2015

Filed:

Jul 3, 2013

Appl. No.:

13/934237

Inventors:

Holger Lange - Enger, DE
Josheph Krueger - Andover MA, US
George Young D. - Boulder CO, US
Trevor Johnson - San Diego CA, US
Frank Voelker - Brewster MA, US
Steven Potts - Phoenix AZ, US

Assignee:

FLAGSHIP BIOSCIENCES, LLC - Boulder CO

International Classification:

G01N 33/50

US Classification:

435 721, 435 4052

Abstract:

Methods for cell-based tissue analysis utilize modern trends in digital microscopy to obtain, process, calibrate, and analyze digital images of tissue sections to quantify cell-based data for improved histological analysis. Using data from multiple images of a common tissue section, or data from images of multiple tissue sections, additional degrees of freedom are realized and the resulting analysis provides added depth to histological analysis of tissue samples. With computerized analytical methods, speed and accuracy of histological analysis is greatly improved.