Steven P Reed

US Patent:

6586570, Jul 1, 2003

Filed:

Apr 9, 1999

Appl. No.:

09/289198

Inventors:

Tony N. Frudakis - Sarasota FL
Steven G. Reed - Bellevue WA
John M. Smith - Everett WA
Lynda Misher - Seattle WA

Assignee:

Corixa Corporation - Seattle WA

International Classification:

C07K 1400

US Classification:

530350, 536 231, 435 6, 435 71, 514 2

Abstract:

Compositions and methods for the detection and therapy of breast cancer are disclosed. The compounds provided include nucleotide sequences that are preferentially expressed in breast tumor tissue, as well as polypeptides encoded by such nucleotide sequences. Vaccines and pharmaceutical compositions comprising such compounds are also provided and may be used, for example, for the prevention and treatment of breast cancer. The polypeptides may also be used for the production of antibodies, which are useful for diagnosing and monitoring the progression of breast cancer in a patient.

US Patent:

6828431, Dec 7, 2004

Filed:

Oct 26, 2000

Appl. No.:

09/699295

Inventors:

Tony N. Frudakis - Sarasota FL
Steven G. Reed - Bellevue WA
John M. Smith - Columbia Heights MN
Lynda E. Misher - Seattle WA
Davin C. Dillon - Issaquah WA
Marc W. Retter - Carnation WA
Aijun Wang - Issaquah WA
Yasir A. W. Skeiky - Bellevue WA
Susan L. Harlocker - Seattle WA

Assignee:

Corixa Corporation - Seattle WA

International Classification:

C12Q 170

US Classification:

536 231, 536 243, 536 2433, 435 6, 435 691, 4353201, 436 64, 436813

Abstract:

Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.

US Patent:

6861506, Mar 1, 2005

Filed:

Mar 23, 2000

Appl. No.:

09/534825

Inventors:

Tony N. Frudakis - Sarasota FL, US
John M. Smith - Columbia Heights MN, US
Steven G. Reed - Bellevue WA, US
Lynda E. Misher - Seattle WA, US
Marc W. Retter - Carnation WA, US
Davin C. Dillon - Issaquah WA, US

Assignee:

Corixa Corporation - Seattle WA

International Classification:

A61K038/00
C07K001/00
C07K014/00
C07K017/00
C07K002/00

US Classification:

530350, 530300, 536 1, 536 187, 536 221, 536 231, 536 235, 514 1, 514 2, 514 12, 514 13, 514 14, 514 15, 514 16, 514 17, 514 18, 514 19, 424 91, 424 92

Abstract:

Compositions and methods for the detection and therapy of breast cancer are disclosed. The compounds provided include nucleotide sequences that are preferentially expressed in breast tumor tissue, as well as polypeptides encoded by such nucleotide sequences. Vaccines and pharmaceutical compositions comprising such compounds are also provided and may be used, for example, for the prevention and treatment of breast cancer. The polypeptides may also be used for the production of antibodies, which are useful for diagnosing and monitoring the progression of breast cancer in a patient.

US Patent:

7241876, Jul 10, 2007

Filed:

Aug 7, 2001

Appl. No.:

09/924400

Inventors:

Tony N. Frudakis - Sarasota FL, US
Steven G. Reed - Bellevue WA, US
John M. Smith - Columbia Heights MN, US
Lynda E. Misher - Seattle WA, US
Davin C. Dillon - Issaquah WA, US
Marc W. Retter - Carnation WA, US
Aijun Wang - Issaquah WA, US
Yasir A. W. Skeiky - Bellevue WA, US
Susan L. Harlocker - Seattle WA, US
Craig H. Day - Shoreline WA, US
Samuel X. Li - Redmond WA, US
Ta Deng - Edmonds WA, US

Assignee:

Corixa Corporation - Hamilton MT

International Classification:

C07H 21/02

US Classification:

536 231, 536 235, 536 243, 536 2431, 514 44, 435 6, 4353201, 436501

Abstract:

Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.

US Patent:

20020068285, Jun 6, 2002

Filed:

Mar 16, 2001

Appl. No.:

09/810936

Inventors:

Tony Frudakis - Sarasota FL, US
Steven Reed - Bellevue WA, US
John Smith - Columbia Heights MN, US
Lynda Misher - Seattle WA, US
Davin Dillon - Issaquah WA, US
Marc Retter - Carnation WA, US
Aijun Wang - Issaquah WA, US
Yasir Skeiky - Bellevue WA, US
Susan Harlocker - Seattle WA, US
Craig Day - Seattle WA, US

International Classification:

C12Q001/68
G01N033/574
C07H021/04
C12P021/04
C12N005/06

US Classification:

435/006000, 435/007230, 435/069700, 536/023100, 435/325000

Abstract:

Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.

US Patent:

20040073016, Apr 15, 2004

Filed:

Feb 20, 2002

Appl. No.:

10/079137

Inventors:

Tony Frudakis - Sarasota FL, US
Steven Reed - Bellevue WA, US
John Smith - Columbia Heights MN, US
Lynda Misher - Seattle WA, US
Davin Dillon - Issaquah WA, US
Marc Retter - Carnation WA, US
Aijun Wang - Issaquah WA, US
Yasir Skeiky - Bellevue WA, US
Susan Harlocker - Seattle WA, US
Craig Day - Shoreline WA, US
Samuel Li - Redmond WA, US
Ta Deng - Edmonds WA, US

Assignee:

Corixa Corporation - Seattle WA

International Classification:

C12Q001/68
G01N033/574
C07H021/04
C07K014/705
C07K016/30

US Classification:

536/023200, 435/006000, 435/069100, 435/007230, 435/320100, 435/325000, 530/350000, 530/388800

Abstract:

Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.